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Livnat Jerby-Arnon
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Perturb-Seq: dissecting molecular circuits with scalable single-cell RNA profiling of pooled genetic screens
A Dixit, O Parnas, B Li, J Chen, CP Fulco, L Jerby-Arnon, ND Marjanovic, ...
cell 167 (7), 1853-1866. e17, 2016
8932016
A cancer cell program promotes T cell exclusion and resistance to checkpoint blockade
L Jerby-Arnon, P Shah, MS Cuoco, C Rodman, MJ Su, JC Melms, ...
Cell 175 (4), 984-997. e24, 2018
6462018
Predicting selective drug targets in cancer through metabolic networks
O Folger, L Jerby, C Frezza, E Gottlieb, E Ruppin, T Shlomi
Molecular systems biology 7 (1), 501, 2011
5322011
Haem oxygenase is synthetically lethal with the tumour suppressor fumarate hydratase
C Frezza, L Zheng, O Folger, KN Rajagopalan, ED MacKenzie, L Jerby, ...
Nature 477 (7363), 225-228, 2011
4882011
Computational reconstruction of tissue-specific metabolic models: application to human liver metabolism
J Livnat, S Tomer, E Ruppin
Molecular systems biology 6 (1), 2010
4022010
Integrative molecular and clinical modeling of clinical outcomes to PD1 blockade in patients with metastatic melanoma
D Liu, B Schilling, D Liu, A Sucker, E Livingstone, L Jerby-Arnon, ...
Nature medicine 25 (12), 1916-1927, 2019
3032019
Predicting cancer-specific vulnerability via data-driven detection of synthetic lethality
L Jerby-Arnon, N Pfetzer, YY Waldman, L McGarry, D James, E Shanks, ...
Cell 158 (5), 1199-1209, 2014
2432014
Fumarate induces redox-dependent senescence by modifying glutathione metabolism
L Zheng, S Cardaci, L Jerby, ED MacKenzie, M Sciacovelli, TI Johnson, ...
Nature communications 6 (1), 1-12, 2015
2082015
A single-cell and single-nucleus RNA-Seq toolbox for fresh and frozen human tumors
M Slyper, C Porter, O Ashenberg, J Waldman, E Drokhlyansky, I Wakiro, ...
Nature medicine 26 (5), 792-802, 2020
1852020
Metabolic associations of reduced proliferation and oxidative stress in advanced breast cancer
L Jerby, L Wolf, C Denkert, GY Stein, M Hilvo, M Oresic, T Geiger, ...
Cancer research 72 (22), 5712-5720, 2012
1432012
A single-cell landscape of high-grade serous ovarian cancer
B Izar, I Tirosh, EH Stover, I Wakiro, MS Cuoco, I Alter, C Rodman, ...
Nature Medicine 26 (8), 1271-1279, 2020
1382020
Predicting drug targets and biomarkers of cancer via genome-scale metabolic modeling
L Jerby, E Ruppin
Clinical Cancer Research 18 (20), 5572-5584, 2012
1092012
Genome-scale study reveals reduced metabolic adaptability in patients with non-alcoholic fatty liver disease
T Hyötyläinen, L Jerby, EM Petäjä, I Mattila, S Jäntti, P Auvinen, ...
Nature communications 7 (1), 1-9, 2016
932016
Inhibitory CD161 receptor identified in glioma-infiltrating T cells by single-cell analysis
ND Mathewson, O Ashenberg, I Tirosh, S Gritsch, EM Perez, S Marx, ...
Cell 184 (5), 1281-1298. e26, 2021
912021
Harnessing synthetic lethality to predict the response to cancer treatment
JS Lee, A Das, L Jerby-Arnon, R Arafeh, N Auslander, M Davidson, ...
Nature communications 9 (1), 1-12, 2018
742018
Multimodal pooled Perturb-CITE-seq screens in patient models define mechanisms of cancer immune evasion
CJ Frangieh, JC Melms, PI Thakore, KR Geiger-Schuller, P Ho, ...
Nature genetics 53 (3), 332-341, 2021
462021
IL-33 signaling alters regulatory T cell diversity in support of tumor development
A Li, RH Herbst, D Canner, JM Schenkel, OC Smith, JY Kim, M Hillman, ...
Cell reports 29 (10), 2998-3008. e8, 2019
412019
Opposing immune and genetic mechanisms shape oncogenic programs in synovial sarcoma
L Jerby-Arnon, C Neftel, ME Shore, HR Weisman, ND Mathewson, ...
Nature medicine 27 (2), 289-300, 2021
362021
A distinct transcriptional program in human CAR T cells bearing the 4-1BB signaling domain revealed by scRNA-seq
AC Boroughs, RC Larson, ND Marjanovic, K Gosik, AP Castano, ...
Molecular Therapy 28 (12), 2577-2592, 2020
322020
Inter-cellular CRISPR screens reveal regulators of cancer cell phagocytosis
RA Kamber, Y Nishiga, B Morton, AM Banuelos, AA Barkal, ...
Nature 597 (7877), 549-554, 2021
232021
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