YAP/TAZ as mechanosensors and mechanotransducers in regulating organ size and tumor growth BC Low, CQ Pan, GV Shivashankar, A Bershadsky, M Sudol, M Sheetz FEBS letters 588 (16), 2663-2670, 2014 | 466 | 2014 |
Sprouty2 attenuates epidermal growth factor receptor ubiquitylation and endocytosis, and consequently enhances Ras/ERK signalling ESM Wong, CW Fong, J Lim, P Yusoff, BC Low, WY Langdon, GR Guy The EMBO journal, 2002 | 271 | 2002 |
Structural basis for the allosteric inhibitory mechanism of human kidney-type glutaminase (KGA) and its regulation by Raf-Mek-Erk signaling in cancer cell metabolism K Thangavelu, CQ Pan, T Karlberg, G Balaji, M Uttamchandani, V Suresh, ... Proceedings of the National Academy of Sciences 109 (20), 7705-7710, 2012 | 243 | 2012 |
YAP regulates actin dynamics through ARHGAP29 and promotes metastasis Y Qiao, J Chen, YB Lim, ML Finch-Edmondson, VP Seshachalam, L Qin, ... Cell reports 19 (8), 1495-1502, 2017 | 217 | 2017 |
In-Silico Approaches to Multi-target Drug Discovery: Computer Aided Multi-target Drug Design, Multi-target Virtual Screening XH Ma, Z Shi, C Tan, Y Jiang, ML Go, BC Low, YZ Chen Pharmaceutical research 27, 739-749, 2010 | 183 | 2010 |
Cortactin phosphorylation as a switch for actin cytoskeletal network and cell dynamics control BL Lua, BC Low FEBS letters 579 (3), 577-585, 2005 | 165 | 2005 |
Evidence for direct interaction between Sprouty and Cbl ESM Wong, J Lim, BC Low, Q Chen, GR Guy Journal of Biological Chemistry 276 (8), 5866-5875, 2001 | 151 | 2001 |
Mechanobiology of tumor growth PK Chaudhuri, BC Low, CT Lim Chemical reviews 118 (14), 6499-6515, 2018 | 146 | 2018 |
RhoA acts downstream of Wnt5 and Wnt11 to regulate convergence and extension movements by involving effectors Rho kinase and Diaphanous: use of zebrafish as an in vivo model … S Zhu, L Liu, V Korzh, Z Gong, BC Low Cellular signalling 18 (3), 359-372, 2006 | 138 | 2006 |
A genetic pathway composed of Sox14 and Mical governs severing of dendrites during pruning D Kirilly, Y Gu, Y Huang, Z Wu, A Bashirullah, BC Low, AL Kolodkin, ... Nature neuroscience 12 (12), 1497-1505, 2009 | 137 | 2009 |
Sprouty proteins are targeted to membrane ruffles upon growth factor receptor tyrosine kinase activation: identification of a novel translocation domain J Lim, ESM Wong, SH Ong, P Yusoff, BC Low, GR Guy Journal of Biological Chemistry 275 (42), 32837-32845, 2000 | 123 | 2000 |
Mutations in six nephrosis genes delineate a pathogenic pathway amenable to treatment S Ashraf, H Kudo, J Rao, A Kikuchi, E Widmeier, JA Lawson, W Tan, ... Nature communications 9 (1), 1960, 2018 | 120 | 2018 |
A Cdo–Bnip-2–Cdc42 signaling pathway regulates p38α/β MAPK activity and myogenic differentiation JS Kang, GU Bae, MJ Yi, YJ Yang, JE Oh, G Takaesu, YT Zhou, BC Low, ... The Journal of cell biology 182 (3), 497-507, 2008 | 117 | 2008 |
Structural basis for the active site inhibition mechanism of human kidney-type glutaminase (KGA) K Thangavelu, QY Chong, BC Low, J Sivaraman Scientific reports 4 (1), 3827, 2014 | 113 | 2014 |
Modularity and functional plasticity of scaffold proteins as p (l) acemakers in cell signaling CQ Pan, M Sudol, M Sheetz, BC Low Cellular signalling 24 (11), 2143-2165, 2012 | 107 | 2012 |
Crosstalk of Ras and Rho: activation of RhoA abates Kras-induced liver tumorigenesis in transgenic zebrafish models TW Chew, XJ Liu, L Liu, JM Spitsbergen, Z Gong, BC Low Oncogene 33 (21), 2717-2727, 2014 | 103 | 2014 |
Interleukin-1βand Tumor Necrosis Factor-α Stimulate the cat-2 Gene of the L-Arginine Transporter in Cultured Vascular Smooth Muscle Cells (∗) DJ Gill, BC Low, MR Grigor Journal of Biological Chemistry 271 (19), 11280-11283, 1996 | 89 | 1996 |
Large-scale curvature sensing by directional actin flow drives cellular migration mode switching T Chen, A Callan-Jones, E Fedorov, A Ravasio, A Brugués, HT Ong, ... Nature physics 15 (4), 393-402, 2019 | 84 | 2019 |
The SAM domain of the RhoGAP DLC1 binds EF1A1 to regulate cell migration D Zhong, J Zhang, S Yang, UJK Soh, JP Buschdorf, YT Zhou, D Yang, ... Journal of cell science 122 (3), 414-424, 2009 | 78 | 2009 |
Virtual screening of selective multitarget kinase inhibitors by combinatorial support vector machines XH Ma, R Wang, CY Tan, YY Jiang, T Lu, HB Rao, XY Li, ML Go, BC Low, ... Molecular pharmaceutics 7 (5), 1545-1560, 2010 | 73 | 2010 |