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Marcela Preininger
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Blood-brain barrier dysfunction in aging induces hyperactivation of TGFβ signaling and chronic yet reversible neural dysfunction
VV Senatorov, AR Friedman, DZ Milikovsky, J Ofer, R Saar-Ashkenazy, ...
Science Translational Medicine 11 (521), 2019
1952019
Simulated microgravity and 3D culture enhance induction, viability, proliferation and differentiation of cardiac progenitors from human pluripotent stem cells
R Jha, Q Wu, M Singh, MK Preininger, P Han, G Ding, HC Cho, H Jo, ...
Scientific Reports 6, 30956, 2016
862016
Pathological conditioning of human neutrophils recruited to the airway milieu in cystic fibrosis
OA Forrest, SA Ingersoll, MK Preininger, J Laval, DH Limoli, MR Brown, ...
Journal of Leukocyte Biology 104 (4), 665-675, 2018
792018
Mature cystic fibrosis airway neutrophils suppress T cell function: evidence for a role of arginase 1, but not programmed death-ligand 1
SA Ingersoll, J Laval, OA Forrest, MK Preininger, MR Brown, D Arafat, ...
The Journal of Immunology 194 (11), 5520-5528, 2015
792015
Microscale generation of cardiospheres promotes robust enrichment of cardiomyocytes derived from human pluripotent stem cells
DC Nguyen, TA Hookway, Q Wu, R Jha, MK Preininger, X Chen, ...
Stem Cell Reports 3 (2), 260-268, 2014
792014
Blood-informative transcripts define nine common axes of peripheral blood gene expression
MK Preininger, D Arafat, J Kim, AP Nath, Y Idaghdour, KL Brigham, ...
PLOS Genetics 9 (3), e1003362, 2013
642013
A human pluripotent stem cell model of catecholaminergic polymorphic ventricular tachycardia recapitulates patient-specific drug responses
MK Preininger, R Jha, JT Maxwell, Q Wu, M Singh, B Wang, A Dalal, ...
Disease Models and Mechanisms 9 (9), 927-939, 2016
622016
Targeting HIF-1α in combination with PPARα activation and postnatal factors promotes the metabolic maturation of human induced pluripotent stem cell-derived cardiomyocytes
C Gentillon, D Li, M Duan, WM Yu, MK Preininger, R Jha, A Rampoldi, ...
Journal of Molecular and Cellular Cardiology 132, 120-135, 2019
592019
Blood–brain barrier dysfunction and astrocyte senescence as reciprocal drivers of neuropathology in aging
MK Preininger, D Kaufer
International Journal of Molecular Sciences 23 (11), 6217, 2022
272022
Targeted elimination of tumorigenic human pluripotent stem cells using suicide-inducing virus-like particles
MK Preininger*, A Rampoldi*, SN Crooke*, R Jha, J Maxwell, L Ding, ...
ACS Chemical Biology 13 (8), 2329–2338, 2018
192018
Cryopreservation of human pluripotent stem cell-derived cardiomyocytes: strategies, challenges, and future directions
MK Preininger, M Singh, C Xu
Advances in Experimental Medicine and Biology 941, 123-135, 2016
182016
Downregulation of LGR5 expression inhibits cardiomyocyte differentiation and potentiates endothelial differentiation from human pluripotent stem cells
R Jha, M Singh, Q Wu, C Gentillon, MK Preininger, C Xu
Stem Cell Reports 9 (2), 513-527, 2017
152017
Geographical, environmental and pathophysiological influences on the human blood transcriptome
R Tabassum, A Nath, MK Preininger, G Gibson
Current Genetic Medicine Reports 1 (4), 203-211, 2013
102013
Blood-brain barrier dysfunction promotes astrocyte senescence through albumin-induced TGFβ signaling activation
MK Preininger, D Zaytseva, JM Lin, D Kaufer
Aging Cell 22 (2), e13747, 2023
92023
Phf15—a novel transcriptional repressor regulating inflammation in mouse microglia
SE Muroy, GA Timblin, MK Preininger, P Cedillo, K Saijo
Neuroimmunology and Neuroinflammation 7, 166-182, 2020
22020
Arginase-1 and programmed cell death ligand-1, potent inducers of immune tolerance, are upregulated on airway neutrophils in cystic fibrosis
S Ingersoll, J Laval, MK Preininger, M Brown, R Tirouvanziam
Pediatric Pulmonology 48 (S36), 258-258, 2013
12013
In vitro transmigration of neutrophils into CF airway fluid induces functional and metabolic reprogramming characteristic of CF airway neutrophils in vivo
OA Forrest, S Ingersoll, M Preininger, J Laval, D Limoli, MR Brown, F Lee, ...
Pediatric Pulmonology 51 (S45), 241-241, 2016
2016
Functional and metabolic reprogramming drives the development of a pathogenic subset of neutrophils in inflammatory airway diseases
O Forrest, S Ingersoll, M Preininger, J Laval, D Limoli, M Brown, F Lee, ...
European Journal of Immunology 46 (S1), 251-252, 2016
2016
Induced pluripotent stem cell-derived cardiomyocytes recapitulate clinically observed refractoriness to therapeutic β-blockade in a patient-specific model of catecholaminergic …
MK Preininger, R Jha, Q Wu, M Singh, JT Maxwell, B Wang, PS Fischbach, ...
Circulation 132 (S3), A15566, 2015
2015
Increased survival and exocytosis of toxic primary granules by neutrophils in an in vitro model of cystic fibrosis airway disease
O Forrest, S Ingersoll, M Preininger, J Laval, M Brown, R Tirouvanziam
The Journal of Immunology 194 (S1), 192-192, 2015
2015
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