FREAD revisited: accurate loop structure prediction using a database search algorithm Y Choi, CM Deane Proteins: Structure, Function, and Bioinformatics 78 (6), 1431-1440, 2010 | 199 | 2010 |
Predicting antibody complementarity determining region structures without classification Y Choi, CM Deane Molecular Biosystems 7 (12), 3327-3334, 2011 | 81 | 2011 |
Antibody humanization by structure-based computational protein design Y Choi, C Hua, CL Sentman, ME Ackerman, C Bailey-Kellogg MAbs 7 (6), 1045-1057, 2015 | 65 | 2015 |
Structure-guided deimmunization of therapeutic proteins AS Parker, Y Choi, KE Griswold, C Bailey-Kellogg Journal of Computational Biology 20 (2), 152-165, 2013 | 64 | 2013 |
Depletion of T cell epitopes in lysostaphin mitigates anti-drug antibody response and enhances antibacterial efficacy in vivo H Zhao, D Verma, W Li, Y Choi, C Ndong, SN Fiering, C Bailey-Kellogg, ... Chemistry & biology 22 (5), 629-639, 2015 | 56 | 2015 |
Structure-based redesign of lysostaphin yields potent antistaphylococcal enzymes that evade immune cell surveillance K Blazanovic, H Zhao, Y Choi, W Li, RS Salvat, DC Osipovitch, J Fields, ... Molecular therapy Methods & clinical development 2, 2015 | 43 | 2015 |
Computationally-driven identification of antibody epitopes CK Hua, AT Gacerez, CL Sentman, ME Ackerman, Y Choi, ... Elife 6, e29023, 2017 | 42 | 2017 |
Gene and protein sequence optimization for high-level production of fully active and aglycosylated lysostaphin in Pichia pastoris H Zhao, K Blazanovic, Y Choi, C Bailey-Kellogg, KE Griswold Applied and environmental microbiology 80 (9), 2746-2753, 2014 | 41 | 2014 |
EpiSweep: Computationally driven reengineering of therapeutic proteins to reduce immunogenicity while maintaining function Y Choi, D Verma, KE Griswold, C Bailey-Kellogg Computational Protein Design, 375-398, 2017 | 32 | 2017 |
Protein deimmunization via structure‐based design enables efficient epitope deletion at high mutational loads RS Salvat, Y Choi, A Bishop, C Bailey‐Kellogg, KE Griswold Biotechnology and bioengineering 112 (7), 1306-1318, 2015 | 31 | 2015 |
Mapping the Pareto optimal design space for a functionally deimmunized biotherapeutic candidate RS Salvat, AS Parker, Y Choi, C Bailey-Kellogg, KE Griswold PLoS computational biology 11 (1), e1003988, 2015 | 29 | 2015 |
Computationally driven deletion of broadly distributed T cell epitopes in a biotherapeutic candidate RS Salvat, AS Parker, A Guilliams, Y Choi, C Bailey-Kellogg, KE Griswold Cellular and molecular life sciences 71, 4869-4880, 2014 | 27 | 2014 |
GradDock: rapid simulation and tailored ranking functions for peptide-MHC Class I docking HH Kyeong, Y Choi, HS Kim Bioinformatics 34 (3), 469-476, 2018 | 23 | 2018 |
How long is a piece of loop? Y Choi, S Agarwal, CM Deane PeerJ 1, e1, 2013 | 23 | 2013 |
Deimmunization of flagellin for repeated administration as a vaccine adjuvant K Khim, YJ Bang, S Puth, Y Choi, YS Lee, K Jeong, SE Lee, JH Rhee npj Vaccines 6 (1), 116, 2021 | 18 | 2021 |
Structure‐based redesign of proteins for minimal T‐cell epitope content Y Choi, KE Griswold, C Bailey‐Kellogg Journal of computational chemistry 34 (10), 879-891, 2013 | 18 | 2013 |
Computationally driven antibody engineering enables simultaneous humanization and thermostabilization Y Choi, C Ndong, KE Griswold, C Bailey-Kellogg Protein Engineering, Design and Selection 29 (10), 419-426, 2016 | 17 | 2016 |
Fragment‐based modeling of membrane protein loops: Successes, failures, and prospects for the future S Kelm, A Vangone, Y Choi, JP Ebejer, J Shi, CM Deane Proteins: Structure, Function, and Bioinformatics 82 (2), 175-186, 2014 | 14 | 2014 |
Repeat module‐based rational design of a photoswitchable protein for light‐driven control of biological processes W Heu, JM Choi, HH Kyeong, Y Choi, HY Kim, HS Kim Angewandte Chemie 130 (34), 11025-11029, 2018 | 12 | 2018 |
DisruPPI: structure-based computational redesign algorithm for protein binding disruption Y Choi, JM Furlon, RB Amos, KE Griswold, C Bailey-Kellogg Bioinformatics 34 (13), i245-i253, 2018 | 12 | 2018 |