| Walking along chromosomes with super-resolution imaging, contact maps, and integrative modeling G Nir, I Farabella, C Pérez Estrada, CG Ebeling, BJ Beliveau, HM Sasaki, ... PLoS genetics 14 (12), e1007872, 2018 | 235 | 2018 |
| Human DNA ligases I and III, but not ligase IV, are required for microhomology-mediated end joining of DNA double-strand breaks L Liang, L Deng, SC Nguyen, X Zhao, CD Maulion, C Shao, JA Tischfield Nucleic acids research 36 (10), 3297-3310, 2008 | 207 | 2008 |
| OligoMiner provides a rapid, flexible environment for the design of genome-scale oligonucleotide in situ hybridization probes BJ Beliveau, JY Kishi, G Nir, HM Sasaki, SK Saka, SC Nguyen, C Wu, ... Proceedings of the National Academy of Sciences 115 (10), E2183-E2192, 2018 | 181 | 2018 |
| Large-scale topological changes restrain malignant progression in colorectal cancer SE Johnstone, A Reyes, Y Qi, C Adriaens, E Hegazi, K Pelka, JH Chen, ... Cell 182 (6), 1474-1489. e23, 2020 | 141 | 2020 |
| 3D mapping and accelerated super-resolution imaging of the human genome using in situ sequencing HQ Nguyen, S Chattoraj, D Castillo, SC Nguyen, G Nir, A Lioutas, ... Nature methods 17 (8), 822-832, 2020 | 111 | 2020 |
| Cohesin promotes stochastic domain intermingling to ensure proper regulation of boundary-proximal genes JM Luppino, DS Park, SC Nguyen, Y Lan, Z Xu, R Yunker, EF Joyce Nature genetics 52 (8), 840-848, 2020 | 96 | 2020 |
| Homologous recombination conserves DNA sequence integrity throughout the cell cycle in embryonic stem cells L Serrano, L Liang, Y Chang, L Deng, C Maulion, S Nguyen, JA Tischfield Stem cells and development 20 (2), 363-374, 2011 | 91 | 2011 |
| H3K9me2 orchestrates inheritance of spatial positioning of peripheral heterochromatin through mitosis A Poleshko, CL Smith, SC Nguyen, P Sivaramakrishnan, KG Wong, ... Elife 8, e49278, 2019 | 90 | 2019 |
| Condensin II drives large-scale folding and spatial partitioning of interphase chromosomes in Drosophila nuclei LF Rosin, SC Nguyen, EF Joyce PLoS genetics 14 (7), e1007393, 2018 | 90 | 2018 |
| Oncogenic notch promotes long-range regulatory interactions within hyperconnected 3D cliques J Petrovic, Y Zhou, M Fasolino, N Goldman, GW Schwartz, MR Mumbach, ... Molecular cell 73 (6), 1174-1190. e12, 2019 | 85 | 2019 |
| Core components of the nuclear pore bind distinct states of chromatin and contribute to polycomb repression A Gozalo, A Duke, Y Lan, P Pascual-Garcia, JA Talamas, SC Nguyen, ... Molecular Cell 77 (1), 67-81. e7, 2020 | 70 | 2020 |
| Highly structured homolog pairing reflects functional organization of the Drosophila genome J AlHaj Abed, J Erceg, A Goloborodko, SC Nguyen, RB McCole, W Saylor, ... Nature communications 10 (1), 4485, 2019 | 61 | 2019 |
| p53 mediates target gene association with nuclear speckles for amplified RNA expression KA Alexander, A Coté, SC Nguyen, L Zhang, O Gholamalamdari, ... Molecular cell 81 (8), 1666-1681. e6, 2021 | 55 | 2021 |
| Targeted demethylation at the CDKN1C/p57 locus induces human β cell replication K Ou, M Yu, NG Moss, YJ Wang, AW Wang, SC Nguyen, C Jiang, ... The Journal of Clinical Investigation 129 (1), 209-214, 2019 | 54 | 2019 |
| Methods for detecting and identifying genomic nucleic acids ER Daugharthy, SC Nguyen, C Wu, GM Church US Patent 10,844,426, 2020 | 53 | 2020 |
| The genome-wide multi-layered architecture of chromosome pairing in early Drosophila embryos J Erceg, J AlHaj Abed, A Goloborodko, BR Lajoie, G Fudenberg, ... Nature Communications 10 (1), 4486, 2019 | 52 | 2019 |
| BRD4 orchestrates genome folding to promote neural crest differentiation R Linares-Saldana, W Kim, NA Bolar, H Zhang, BA Koch-Bojalad, S Yoon, ... Nature genetics 53 (10), 1480-1492, 2021 | 50 | 2021 |
| Stably expressed d-genome-derived HMW glutenin subunit genes transformed into different durum wheat genotypes change dough mixing properties A Gadaleta, AE Blechl, S Nguyen, MF Cardone, M Ventura, JS Quick, ... Molecular Breeding 22, 267-279, 2008 | 50 | 2008 |
| Diversification and collapse of a telomere elongation mechanism B Saint-Leandre, SC Nguyen, MT Levine Genome research 29 (6), 920-931, 2019 | 44 | 2019 |
| Chromosome territory formation attenuates the translocation potential of cells LF Rosin, O Crocker, RL Isenhart, SC Nguyen, Z Xu, EF Joyce Elife 8, e49553, 2019 | 38 | 2019 |
Eric JoyceAssociate Professor of Genetics, University of PennsylvaniaE-mail confirmado em upenn.edu
