Jared Auclair
Jared Auclair
Associate Teaching Prof.; Director MS Biotech and Bioinf; Director BATL, APEC CoEs and ICH training
E-mail confirmado em northeastern.edu
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A soluble α-synuclein construct forms a dynamic tetramer
W Wang, I Perovic, J Chittuluru, A Kaganovich, LTT Nguyen, J Liao, ...
Proceedings of the National Academy of Sciences 108 (43), 17797-17802, 2011
4032011
Strategies for stabilizing superoxide dismutase (SOD1), the protein destabilized in the most common form of familial amyotrophic lateral sclerosis
JR Auclair, KJ Boggio, GA Petsko, D Ringe, JN Agar
Proceedings of the National Academy of Sciences 107 (50), 21394-21399, 2010
762010
Mass spectrometry analysis of HIV‐1 Vif reveals an increase in ordered structure upon oligomerization in regions necessary for viral infectivity
JR Auclair, KM Green, S Shandilya, JE Evans, M Somasundaran, ...
Proteins: Structure, Function, and Bioinformatics 69 (2), 270-284, 2007
502007
Best practices and benchmarks for intact protein analysis for top-down mass spectrometry
DP Donnelly, CM Rawlins, CJ DeHart, L Fornelli, LF Schachner, Z Lin, ...
Nature methods 16 (7), 587-594, 2019
432019
Post-translational modification by cysteine protects Cu/Zn-superoxide dismutase from oxidative damage
JR Auclair, JL Johnson, Q Liu, JP Salisbury, MS Rotunno, GA Petsko, ...
Biochemistry 52 (36), 6137-6144, 2013
312013
Identification of a misfolded region in superoxide dismutase 1 that is exposed in amyotrophic lateral sclerosis
MS Rotunno, JR Auclair, S Maniatis, SA Shaffer, J Agar, DA Bosco
Journal of Biological Chemistry 289 (41), 28527-28538, 2014
302014
Mildly acidic conditions eliminate deamidation artifact during proteolysis: digestion with endoprotease Glu-C at pH 4.5
S Liu, KR Moulton, JR Auclair, ZS Zhou
Amino Acids 48 (4), 1059-1067, 2016
212016
Structural consequences of cysteinylation of Cu/Zn-superoxide dismutase
JR Auclair, HR Brodkin, JA D’Aquino, GA Petsko, D Ringe, JN Agar
Biochemistry 52 (36), 6145-6150, 2013
192013
The central nervous system transcriptome of the weakly electric brown ghost knifefish (Apteronotus leptorhynchus): de novo assembly, annotation, and proteomics validation
JP Salisbury, RF Sîrbulescu, BM Moran, JR Auclair, GKH Zupanc, ...
BMC genomics 16 (1), 1-22, 2015
172015
Artifacts to avoid while taking advantage of top‐down mass spectrometry based detection of protein S‐thiolation
JR Auclair, JP Salisbury, JL Johnson, GA Petsko, D Ringe, DA Bosco, ...
Proteomics 14 (10), 1152-1157, 2014
112014
Heavy sugar and heavy water create tunable intact protein mass increases for quantitative mass spectrometry in any feed and organism
JV Quijada, ND Schmitt, JP Salisbury, JR Auclair, JN Agar
Analytical chemistry 88 (22), 11139-11146, 2016
92016
Cyclic thiosulfinates and cyclic disulfides selectively cross-link thiols while avoiding modification of lone thiols
DP Donnelly, MG Dowgiallo, JP Salisbury, KC Aluri, S Iyengar, ...
Journal of the American Chemical Society 140 (24), 7377-7380, 2018
62018
Charge-Variant Profiling of Biopharmaceuticals
JR Auclair, A Rathore, I Krull
LC GC NORTH AMERICA 36 (1), 26-36, 2018
42018
Regulatory Convergence for biologics through capacity building and training
JR Auclair
Trends in biotechnology 37 (1), 5-9, 2019
32019
Integrated Bottom-Up and Top-Down Liquid Chromatography–Mass Spectrometry for Characterization of Recombinant Human Growth Hormone Degradation Products
YA Wang, D Wu, JR Auclair, JP Salisbury, R Sarin, Y Tang, NJ Mozdzierz, ...
Analytical chemistry 89 (23), 12771-12777, 2017
32017
Bayesian Network Based Risk and Sensitivity Analysis for Production Process Stability Control
W Xie, B Wang, C Li, J Auclair, P Baker
arXiv preprint arXiv:1909.04261, 2019
22019
Methods and Purposes for Determining Higher Order Structures of Biopharmaceuticals
ARJ Auclair, A Rathore, IS Krull
LC GC NORTH AMERICA 37 (1), 34-43, 2019
22019
Mass spectrometry tools for analysis of intermolecular interactions
JR Auclair, M Somasundaran, KM Green, JE Evans, CA Schiffer, D Ringe, ...
Intrinsically Disordered Protein Analysis, 387-398, 2012
22012
Shigella flexneri adherence factor expression in in vivo-like conditions
RB Chanin, KP Nickerson, A Llanos-Chea, JR Sistrunk, DA Rasko, ...
Msphere 4 (6), 2019
2019
Genetically Encoded Fluorescent Proteins Enable High-Throughput Assignment of Cell Cohorts Directly from MALDI-MS Images
ND Schmitt, CM Rawlins, EC Randall, X Wang, A Koller, JR Auclair, ...
Analytical chemistry 91 (6), 3810-3817, 2019
2019
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