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Samuel Bowerman
Samuel Bowerman
Scientist, Structural Biology, Loxo Oncology at Lilly
E-mail confirmado em loxooncology.com
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The conformation of the histone H3 tail inhibits association of the BPTF PHD finger with the nucleosome
EA Morrison, S Bowerman, KL Sylvers, J Wereszczynski, CA Musselman
Elife 7, e31481, 2018
1122018
Detecting allosteric networks using molecular dynamics simulation
S Bowerman, J Wereszczynski
Methods in enzymology 578, 429-447, 2016
822016
Effects of MacroH2A and H2A. Z on nucleosome dynamics as elucidated by molecular dynamics simulations
S Bowerman, J Wereszczynski
Biophysical journal 110 (2), 327-337, 2016
572016
Virus-encoded histone doublets are essential and form nucleosome-like structures
Y Liu, H Bisio, CM Toner, S Jeudy, N Philippe, K Zhou, S Bowerman, ...
Cell 184 (16), 4237-4250. e19, 2021
522021
Archaeal chromatin ‘slinkies’ are inherently dynamic complexes with deflected DNA wrapping pathways
S Bowerman, J Wereszczynski, K Luger
Elife 10, e65587, 2021
412021
Bridging of nucleosome-proximal DNA double-strand breaks by PARP2 enhances its interaction with HPF1
G Gaullier, G Roberts, UM Muthurajan, S Bowerman, J Rudolph, ...
PLoS One 15 (11), e0240932, 2020
382020
Analytical ultracentrifugation (AUC): an overview of the application of fluorescence and absorbance AUC to the study of biological macromolecules
GB Edwards, UM Muthurajan, S Bowerman, K Luger
Current protocols in molecular biology 133 (1), e131, 2020
352020
Archaea: the final frontier of chromatin
SP Laursen, S Bowerman, K Luger
Journal of molecular biology 433 (6), 166791, 2021
262021
Determining atomistic SAXS models of tri-ubiquitin chains from bayesian analysis of accelerated molecular dynamics simulations
S Bowerman, ASJB Rana, A Rice, GH Pham, ER Strieter, ...
Journal of chemical theory and computation 13 (6), 2418-2429, 2017
212017
Unique Dynamics in Asymmetric macroH2A–H2A Hybrid Nucleosomes Result in Increased Complex Stability
S Bowerman, RJ Hickok, J Wereszczynski
The Journal of Physical Chemistry B 123 (2), 419-427, 2018
142018
Quantitating repair protein accumulation at DNA lesions: Past, present, and future
J Mahadevan, S Bowerman, K Luger
DNA repair 81, 102650, 2019
112019
Dynamics of endogenous PARP1 and PARP2 during DNA damage revealed by live-cell single-molecule imaging
J Mahadevan, A Jha, J Rudolph, S Bowerman, D Narducci, AS Hansen, ...
IScience 26 (1), 2023
92023
BEES: Bayesian ensemble estimation from SAS
S Bowerman, JE Curtis, J Clayton, EH Brookes, J Wereszczynski
Biophysical Journal 117 (3), 399-407, 2019
72019
Automated modeling of protein accumulation at DNA damage sites using qFADD. py
S Bowerman, J Mahadevan, P Benson, J Rudolph, K Luger
Biological imaging 2, e8, 2022
42022
Melbournevirus-encoded histone doublets are recruited to virus particles and form destabilized nucleosome-like structures
Y Liu, CM Toner, N Philippe, S Jeudy, K Zhou, S Bowerman, A White, ...
bioRxiv, 2021.04. 29.441998, 2021
42021
Adventures in the chromatin jungle: Nucleosome remodelers, archaeal slinkies, and giant viruses
Y Liu, C Toner, S Bowerman, H Bisio, S Jeudy, N Philippe, K Zhou, ...
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS 50 (SUPPL 1), 40-40, 2021
2021
Extracting Protein Recruitment Kinetics to DNA Damage using qFADD. py
S Bowerman, J Mahadevan, P Benson, J Rudolph, K Luger
Biophysical Journal 120 (3), 82a-83a, 2021
2021
Acidic Solutions to Archaeal Chromatin
S Laursen, S Bowerman, K Luger
Biophysical Journal 120 (3), 317a, 2021
2021
The Dynamic Archaeal Chromatin “Slinky”
S Bowerman
Bulletin of the American Physical Society 65, 2020
2020
Elucidating Archaeal Chromatin “Slinky” Dynamics through Simulation and Experiment
S Bowerman, D Kraft, J Wereszczynski, K Luger
Biophysical Journal 118 (3), 9a, 2020
2020
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Artigos 1–20