Toll-like receptor 4 contributes to blood pressure regulation and vascular contraction in spontaneously hypertensive rats GF Bomfim, RAD Santos, MA Oliveira, FR Giachini, EH Akamine, ... Clinical science 122 (11), 535-543, 2012 | 246 | 2012 |
A lower ratio of AT1/AT2 receptors of angiotensin II is found in female than in male spontaneously hypertensive rats MM Silva-Antonialli, RCA Tostes, L Fernandes, DR Fior-Chadi, ... Cardiovascular Research 62 (3), 587-593, 2004 | 228 | 2004 |
Oxidative stress and inflammatory mediators contribute to endothelial dysfunction in high-fat diet-induced obesity in mice R Kobayasi, EH Akamine, AP Davel, MAM Rodrigues, CRO Carvalho, ... Journal of hypertension 28 (10), 2111-2119, 2010 | 203 | 2010 |
Enhanced oxidative stress as a potential mechanism underlying the programming of hypertension in utero MCP Franco, APV Dantas, EH Akamine, EM Kawamoto, ZB Fortes, ... Journal of cardiovascular pharmacology 40 (4), 501-509, 2002 | 158 | 2002 |
Obesity induced by high-fat diet promotes insulin resistance in the ovary EH Akamine, AC Marcal, JP Camporez, MS Hoshida, LC Caperuto, ... Journal of Endocrinology 206 (1), 65, 2010 | 133 | 2010 |
Endothelial dysfunction in cardiovascular and endocrine-metabolic diseases: an update AP Davel, CF Wenceslau, EH Akamine, FE Xavier, GK Couto, HT Oliveira, ... Brazilian Journal of Medical and Biological Research 44, 920-932, 2011 | 122 | 2011 |
Mechanisms of endothelial dysfunction in obesity-associated hypertension NS Lobato, FP Filgueira, EH Akamine, RC Tostes, MHC Carvalho, ... Brazilian Journal of Medical and Biological Research 45, 392-400, 2012 | 116 | 2012 |
NADPH oxidase and enhanced superoxide generation in intrauterine undernourished rats: involvement of the renin–angiotensin system MCP Franco, EH Akamine, GS Di Marco, DE Casarini, ZB Fortes, ... Cardiovascular research 59 (3), 767-775, 2003 | 106 | 2003 |
Toll-like receptor 4 inhibition reduces vascular inflammation in spontaneously hypertensive rats GF Bomfim, C Echem, CB Martins, TJ Costa, SM Sartoretto, ... Life sciences 122, 1-7, 2015 | 89 | 2015 |
Dehydroepiandrosterone protects against oxidative stress‐induced endothelial dysfunction in ovariectomized rats JPG Camporez, EH Akamine, AP Davel, CR Franci, LV Rossoni, ... The Journal of physiology 589 (10), 2585-2596, 2011 | 81 | 2011 |
Modulation of bone morphogenetic protein-9 expression and processing by insulin, glucose, and glucocorticoids: possible candidate for hepatic insulin-sensitizing substance LC Caperuto, GF Anhê, TD Cambiaghi, EH Akamine, ... Endocrinology 149 (12), 6326-6335, 2008 | 70 | 2008 |
Obesity induced by neonatal treatment with monosodium glutamate impairs microvascular reactivity in adult rats: role of NO and prostanoids NS Lobato, FP Filgueira, EH Akamine, APC Davel, LV Rossoni, ... Nutrition, Metabolism and Cardiovascular Diseases 21 (10), 808-816, 2011 | 64 | 2011 |
Long-term effects of intrauterine malnutrition on vascular function in female offspring: implications of oxidative stress MCP Franco, EH Akamine, N Rebouças, MHC Carvalho, RCA Tostes, ... Life Sciences 80 (8), 709-715, 2007 | 62 | 2007 |
Tetrahydrobiopterin improves endothelial dysfunction and vascular oxidative stress in microvessels of intrauterine undernourished rats MCP Franco, ZB Fortes, EH Akamine, EM Kawamoto, C Scavone, ... The Journal of physiology 558 (1), 239-248, 2004 | 56 | 2004 |
H2O2 generated from mitochondrial electron transport chain in thoracic perivascular adipose tissue is crucial for modulation of vascular smooth muscle contraction RM Costa, FP Filgueira, RC Tostes, MHC Carvalho, EH Akamine, ... Vascular Pharmacology 84, 28-37, 2016 | 53 | 2016 |
Association of testosterone with estrogen abolishes the beneficial effects of estrogen treatment by increasing ROS generation in aorta endothelial cells TJ Costa, GS Ceravolo, RA dos Santos, MA de Oliveira, PX Araújo, ... American Journal of Physiology-Heart and Circulatory Physiology 308 (7 …, 2015 | 48 | 2015 |
Improvement of metabolic parameters and vascular function by metformin in obese non-diabetic rats NS Lobato, FP Filgueira, GN Hagihara, EH Akamine, JR Pariz, RC Tostes, ... Life sciences 90 (5-6), 228-235, 2012 | 41 | 2012 |
Systemic arterial hypertension leads to decreased semen quality and alterations in the testicular microcirculation in rats LG Colli, LB Belardin, C Echem, EH Akamine, MP Antoniassi, ... Scientific reports 9 (1), 11047, 2019 | 40 | 2019 |
Correction of endothelial dysfunction in diabetic female rats by tetrahydrobiopterin and chronic insulin EH Akamine, EM Kawamoto, C Scavone, D Nigro, MHC Carvalho, ... Journal of vascular research 43 (4), 309-320, 2006 | 40 | 2006 |
An interaction of renin-angiotensin and kallikrein-kinin systems contributes to vascular hypertrophy in angiotensin II-induced hypertension: in vivo and in vitro studies GS Ceravolo, AC Montezano, MT Jordão, EH Akamine, TJ Costa, ... PloS one 9 (11), e111117, 2014 | 36 | 2014 |