| GQ-16, a novel peroxisome proliferator-activated receptor γ (PPARγ) ligand, promotes insulin sensitization without weight gain AA Amato, S Rajagopalan, JZ Lin, BM Carvalho, ACM Figueira, J Lu, ... Journal of Biological Chemistry 287 (33), 28169-28179, 2012 | 140 | 2012 |
| Anti-inflammatory and antinociceptive activities of indole–imidazolidine derivatives ASH da Silva Guerra, DJ do Nascimento Malta, LPM Laranjeira, ... International Immunopharmacology 11 (11), 1816-1822, 2011 | 123 | 2011 |
| Synthesis and anti-inflammatory activity of new arylidene-thiazolidine-2, 4-diones as PPARγ ligands CD Barros, AA Amato, TB de Oliveira, KBR Iannini, AL da Silva, ... Bioorganic & medicinal chemistry 18 (11), 3805-3811, 2010 | 107 | 2010 |
| Medicinal chemistry of antischistosomal drugs: Praziquantel and oxamniquine VBR da Silva, BRKL Campos, JF de Oliveira, JL Decout, MCA de Lima Bioorganic & medicinal chemistry 25 (13), 3259-3277, 2017 | 102 | 2017 |
| Synthesis, DNA binding, and antiproliferative activity of novel acridine-thiosemicarbazone derivatives SMV Almeida, EA Lafayette, LPB Gomes da Silva, CAC Amorim, ... International journal of molecular sciences 16 (6), 13023-13042, 2015 | 93 | 2015 |
| Prevalence of dementia subtypes in a developing country: a clinicopathological study LT Grinberg, R Nitrini, CK Suemoto, RE de Lucena Ferretti-Rebustini, ... Clinics 68, 1140-1145, 2013 | 91 | 2013 |
| Thiosemicarbazones and 4-thiazolidinones indole-based derivatives: Synthesis, evaluation of antiproliferative activity, cell death mechanisms and topoisomerase inhibition assay JF de Oliveira, TS Lima, DB Vendramini-Costa, SCB de Lacerda Pedrosa, ... European journal of medicinal chemistry 136, 305-314, 2017 | 82 | 2017 |
| Synthesis and cytotoxic activity of new acridine-thiazolidine derivatives FWA Barros, TG Silva, MG da Rocha Pitta, DP Bezerra, LV Costa-Lotufo, ... Bioorganic & medicinal chemistry 20 (11), 3533-3539, 2012 | 82 | 2012 |
| Synthesis, biological evaluation and molecular modeling studies of arylidene-thiazolidinediones with potential hypoglycemic and hypolipidemic activities LFC da Costa Leite, RHV Mourão, MCA de Lima, SL Galdino, ... European journal of medicinal chemistry 42 (10), 1263-1271, 2007 | 78 | 2007 |
| Synthesis of thiophene-thiosemicarbazone derivatives and evaluation of their in vitro and in vivo antitumor activities JF de Oliveira, AL da Silva, DB Vendramini-Costa, CA da Cruz Amorim, ... European journal of medicinal chemistry 104, 148-156, 2015 | 76 | 2015 |
| 2-Amino-thiophene derivatives present antileishmanial activity mediated by apoptosis and immunomodulation in vitro KA da Franca Rodrigues, CN de Sousa Dias, PL do Nascimento Néris, ... European journal of medicinal chemistry 106, 1-14, 2015 | 73 | 2015 |
| Niche for acridine derivatives in anticancer therapy MR Galdino-Pitta, MGR Pitta, MCA Lima, LS Galdino, RI Pitta Mini Rev Med Chem 13 (9), 1256-1271, 2013 | 61 | 2013 |
| Synthesis, DNA binding and topoisomerase I inhibition activity of thiazacridine and imidazacridine derivatives EA Lafayette, V de Almeida, S Mônica, MG Da Rocha Pitta, ... Molecules 18 (12), 15035-15050, 2013 | 54 | 2013 |
| Synthesis of novel indole derivatives as promising DNA-binding agents and evaluation of antitumor and antitopoisomerase I activities EA Lafayette, SMV de Almeida, RVC Santos, JF de Oliveira, ... European journal of medicinal chemistry 136, 511-522, 2017 | 53 | 2017 |
| Synthesis, cytotoxicity and antifungal activity of 5-nitro-thiophene-thiosemicarbazones derivatives LN de Araújo Neto, MCA de Lima, JF de Oliveira, ER de Souza, ... Chemico-biological interactions 272, 172-181, 2017 | 52 | 2017 |
| Antileishmanial activity of new thiophene–indole hybrids: Design, synthesis, biological and cytotoxic evaluation, and chemometric studies MB Félix, ER de Souza, MCA de Lima, DKG Frade, VL Serafim, ... Bioorganic & Medicinal Chemistry 24 (18), 3972-3977, 2016 | 50 | 2016 |
| Novel 4-quinoline-thiosemicarbazone derivatives: Synthesis, antiproliferative activity, in vitro and in silico biomacromolecule interaction studies and topoisomerase inhibition AG Ribeiro, SMV de Almeida, JF de Oliveira, TRC de Lima Souza, ... European Journal of Medicinal Chemistry 182, 111592, 2019 | 48 | 2019 |
| Impact of COVID-19 pandemic on life-space mobility of older adults living in Brazil: REMOBILIZE study MR Perracini, JSC De Amorim, CA Lima, A Da Silva, F Trombini-Souza, ... Frontiers in Public Health 9, 643640, 2021 | 47 | 2021 |
| DNA binding and Topoisomerase inhibition: How can these mechanisms be explored to design more specific anticancer agents? SMV de Almeida, AG Ribeiro, GC de Lima Silva, JEF Alves, EIC Beltrão, ... Biomedicine & Pharmacotherapy 96, 1538-1556, 2017 | 46 | 2017 |
| Preliminary antifungal and cytotoxic evaluation of synthetic cycloalkyl [b] thiophene derivatives with PLS-DA analysis BCC Souza, TB De Oliveira, TM Aquino, MCA de Lima, IR Pitta, ... Acta Pharmaceutica 62 (2), 221-236, 2012 | 46 | 2012 |
