| Thiosemicarbazones from the old to new: iron chelators that are more than just ribonucleotide reductase inhibitors Y Yu, DS Kalinowski, Z Kovacevic, AR Siafakas, PJ Jansson, C Stefani, ... Journal of medicinal chemistry 52 (17), 5271-5294, 2009 | 456 | 2009 |
| Tuning cell cycle regulation with an iron key Y Yu, Z Kovacevic, DR Richardson Cell cycle 6 (16), 1982-1994, 2007 | 280 | 2007 |
| The iron chelators Dp44mT and DFO inhibit TGF-β-induced epithelial-mesenchymal transition via up-regulation of N-Myc downstream-regulated gene 1 (NDRG1) Z Chen, D Zhang, F Yue, M Zheng, Z Kovacevic, DR Richardson Journal of Biological Chemistry 287 (21), 17016-17028, 2012 | 267 | 2012 |
| The metastasis suppressor, Ndrg-1: a new ally in the fight against cancer Z Kovacevic, DR Richardson Carcinogenesis 27 (12), 2355-2366, 2006 | 240 | 2006 |
| Roads to melanoma: Key pathways and emerging players in melanoma progression and oncogenic signaling J Paluncic, Z Kovacevic, PJ Jansson, D Kalinowski, AM Merlot, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1863 (4), 770-784, 2016 | 223 | 2016 |
| Iron chelators for the treatment of cancer Y Yu, E Gutierrez, Z Kovacevic, F Saletta, P Obeidy, Y Suryo Rahmanto, ... Current medicinal chemistry 19 (17), 2689-2702, 2012 | 196 | 2012 |
| Novel thiosemicarbazone iron chelators induce up-regulation and phosphorylation of the metastasis suppressor N-myc down-stream regulated gene 1: a new strategy for the … Z Kovacevic, S Chikhani, DB Lovejoy, DR Richardson Molecular pharmacology 80 (4), 598-609, 2011 | 189 | 2011 |
| The iron-regulated metastasis suppressor NDRG1 targets NEDD4L, PTEN, and SMAD4 and inhibits the PI3K and Ras signaling pathways Z Kovacevic, S Chikhani, GYL Lui, S Sivagurunathan, DR Richardson Antioxidants & redox signaling 18 (8), 874-887, 2013 | 172 | 2013 |
| Targeting cancer by binding iron: Dissecting cellular signaling pathways GYL Lui, Z Kovacevic, V Richardson, AM Merlot, DS Kalinowski, ... Oncotarget 6 (22), 18748, 2015 | 160 | 2015 |
| Molecular functions of the iron-regulated metastasis suppressor, NDRG1, and its potential as a molecular target for cancer therapy BA Fang, Ž Kovačević, KC Park, DS Kalinowski, PJ Jansson, DJR Lane, ... Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1845 (1), 1-19, 2014 | 160 | 2014 |
| The renaissance of polypharmacology in the development of anti-cancer therapeutics: Inhibition of the “Triad of Death” in cancer by Di-2-pyridylketone thiosemicarbazones PJ Jansson, DS Kalinowski, DJR Lane, Z Kovacevic, NA Seebacher, ... Pharmacological research 100, 255-260, 2015 | 154 | 2015 |
| Metastasis suppressor, NDRG1, mediates its activity through signaling pathways and molecular motors J Sun, D Zhang, DH Bae, S Sahni, P Jansson, Y Zheng, Q Zhao, F Yue, ... Carcinogenesis 34 (9), 1943-1954, 2013 | 148 | 2013 |
| Redox cycling metals: Pedaling their roles in metabolism and their use in the development of novel therapeutics DS Kalinowski, C Stefani, S Toyokuni, T Ganz, GJ Anderson, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1863 (4), 727-748, 2016 | 141 | 2016 |
| The iron chelator, deferasirox, as a novel strategy for cancer treatment: oral activity against human lung tumor xenografts and molecular mechanism of action GYL Lui, P Obeidy, SJ Ford, C Tselepis, DM Sharp, PJ Jansson, ... Molecular pharmacology 83 (1), 179-190, 2013 | 140 | 2013 |
| Dp44mT targets the AKT, TGF-β and ERK pathways via the metastasis suppressor NDRG1 in normal prostate epithelial cells and prostate cancer cells KM Dixon, GYL Lui, Z Kovacevic, D Zhang, M Yao, Z Chen, Q Dong, ... British journal of cancer 108 (2), 409-419, 2013 | 130 | 2013 |
| The emerging role of progesterone receptor membrane component 1 (PGRMC1) in cancer biology MA Cahill, JA Jazayeri, SM Catalano, S Toyokuni, Z Kovacevic, ... Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1866 (2), 339-349, 2016 | 122 | 2016 |
| The TGF-β, PI3K/Akt and PTEN pathways: established and proposed biochemical integration in prostate cancer SJ Assinder, Q Dong, Z Kovacevic, DR Richardson Biochemical Journal 417 (2), 411-421, 2009 | 121 | 2009 |
| The role of NDRG1 in the pathology and potential treatment of human cancers DH Bae, PJ Jansson, ML Huang, Z Kovacevic, D Kalinowski, CS Lee, ... Journal of clinical pathology 66 (11), 911-917, 2013 | 118 | 2013 |
| The metastasis suppressor NDRG1 modulates the phosphorylation and nuclear translocation of β-catenin through mechanisms involving FRAT1 and PAK4 R Jin, W Liu, S Menezes, F Yue, M Zheng, Z Kovacevic, DR Richardson Journal of cell science 127 (14), 3116-3130, 2014 | 113 | 2014 |
| Expanding horizons in iron chelation and the treatment of cancer: Role of iron in the regulation of ER stress and the epithelial–mesenchymal transition DJR Lane, TM Mills, NH Shafie, AM Merlot, RS Moussa, DS Kalinowski, ... Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1845 (2), 166-181, 2014 | 110 | 2014 |
