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David Kent
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Somatic CALR mutations in myeloproliferative neoplasms with nonmutated JAK2
J Nangalia, CE Massie, EJ Baxter, FL Nice, G Gundem, DC Wedge, ...
New England Journal of Medicine 369 (25), 2391-2405, 2013
21102013
Long-term propagation of distinct hematopoietic differentiation programs in vivo
B Dykstra, D Kent, M Bowie, L McCaffrey, M Hamilton, K Lyons, SJ Lee, ...
Cell Stem Cell 1 (2), 218-229, 2007
7252007
A single-cell resolution map of mouse hematopoietic stem and progenitor cell differentiation
S Nestorowa, FK Hamey, B Pijuan Sala, E Diamanti, M Shepherd, ...
Blood, The Journal of the American Society of Hematology 128 (8), e20-e31, 2016
6722016
Effect of mutation order on myeloproliferative neoplasms
CA Ortmann, DG Kent, J Nangalia, Y Silber, DC Wedge, J Grinfeld, ...
New England Journal of Medicine 372 (7), 601-612, 2015
5862015
Population dynamics of normal human blood inferred from somatic mutations
H Lee-Six, NF Øbro, MS Shepherd, S Grossmann, K Dawson, M Belmonte, ...
Nature 561 (7724), 473-478, 2018
4832018
Combined single-cell functional and gene expression analysis resolves heterogeneity within stem cell populations
NK Wilson, DG Kent, F Buettner, M Shehata, IC Macaulay, ...
Cell stem cell 16 (6), 712-724, 2015
4722015
Hematopoietic stem cells proliferate until after birth and show a reversible phase-specific engraftment defect
MB Bowie, KD McKnight, DG Kent, L McCaffrey, PA Hoodless, CJ Eaves
The Journal of clinical investigation 116 (10), 2808-2816, 2006
4112006
Prospective isolation and molecular characterization of hematopoietic stem cells with durable self-renewal potential
DG Kent, MR Copley, C Benz, S Wöhrer, BJ Dykstra, E Ma, J Cheyne, ...
Blood, The Journal of the American Society of Hematology 113 (25), 6342-6350, 2009
3922009
High-throughput analysis of single hematopoietic stem cell proliferation in microfluidic cell culture arrays
V Lecault, M VanInsberghe, S Sekulovic, DJHF Knapp, S Wohrer, ...
Nature methods 8 (7), 581-586, 2011
3742011
Hematopoietic stem cell subtypes expand differentially during development and display distinct lymphopoietic programs
C Benz, MR Copley, DG Kent, S Wohrer, A Cortes, N Aghaeepour, E Ma, ...
Cell stem cell 10 (3), 273-283, 2012
3662012
The unfolded protein response governs integrity of the haematopoietic stem-cell pool during stress
P van Galen, A Kreso, N Mbong, DG Kent, T Fitzmaurice, JE Chambers, ...
Nature 510 (7504), 268-272, 2014
3652014
The Lin28b–let-7–Hmga2 axis determines the higher self-renewal potential of fetal haematopoietic stem cells
MR Copley, S Babovic, C Benz, DJHF Knapp, PA Beer, DG Kent, ...
Nature cell biology 15 (8), 916-925, 2013
3522013
Identification of a new intrinsically timed developmental checkpoint that reprograms key hematopoietic stem cell properties
MB Bowie, DG Kent, B Dykstra, KD McKnight, L McCaffrey, PA Hoodless, ...
Proceedings of the National Academy of Sciences 104 (14), 5878-5882, 2007
2982007
Somatic mutation landscapes at single-molecule resolution
F Abascal, LMR Harvey, E Mitchell, ARJ Lawson, SV Lensing, P Ellis, ...
Nature 593 (7859), 405-410, 2021
2882021
Regulation of hematopoietic stem cells by the steel factor/KIT signaling pathway
D Kent, M Copley, C Benz, B Dykstra, M Bowie, C Eaves
Clinical Cancer Research 14 (7), 1926-1930, 2008
2372008
Comprehensive microRNA expression profiling of the hematopoietic hierarchy
OI Petriv, F Kuchenbauer, AD Delaney, V Lecault, A White, D Kent, ...
Proceedings of the National Academy of Sciences 107 (35), 15443-15448, 2010
2002010
A single-cell hematopoietic landscape resolves 8 lineage trajectories and defects in Kit mutant mice
JS Dahlin, FK Hamey, B Pijuan-Sala, M Shepherd, WWY Lau, ...
Blood, The Journal of the American Society of Hematology 131 (21), e1-e11, 2018
1852018
Clonal dynamics of haematopoiesis across the human lifespan
E Mitchell, M Spencer Chapman, N Williams, KJ Dawson, N Mende, ...
Nature 606 (7913), 343-350, 2022
1842022
High-resolution video monitoring of hematopoietic stem cells cultured in single-cell arrays identifies new features of self-renewal
B Dykstra, J Ramunas, D Kent, L McCaffrey, E Szumsky, L Kelly, K Farn, ...
Proceedings of the National Academy of Sciences 103 (21), 8185-8190, 2006
1662006
Steel factor responsiveness regulates the high self-renewal phenotype of fetal hematopoietic stem cells
MB Bowie, DG Kent, MR Copley, CJ Eaves
Blood, The Journal of the American Society of Hematology 109 (11), 5043-5048, 2007
1492007
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