| Twenty proteins containing a C-terminal SOCS box form five structural classes DJ Hilton, RT Richardson, WS Alexander, EM Viney, TA Willson, ... Proceedings of the National Academy of Sciences 95 (1), 114-119, 1998 | 941 | 1998 |
| The conserved SOCS box motif in suppressors of cytokine signaling binds to elongins B and C and may couple bound proteins to proteasomal degradation JG Zhang, A Farley, SE Nicholson, TA Willson, LM Zugaro, RJ Simpson, ... Proceedings of the National Academy of Sciences 96 (5), 2071-2076, 1999 | 807 | 1999 |
| SOCS regulation of the JAK/STAT signalling pathway BA Croker, H Kiu, SE Nicholson Seminars in cell & developmental biology 19 (4), 414-422, 2008 | 798 | 2008 |
| Suppressor of cytokine signaling 1 negatively regulates Toll-like receptor signaling by mediating Mal degradation A Mansell, R Smith, SL Doyle, P Gray, JE Fenner, PJ Crack, SE Nicholson, ... Nature immunology 7 (2), 148-155, 2006 | 663 | 2006 |
| Suppressor of cytokine signaling-3 preferentially binds to the SHP-2-binding site on the shared cytokine receptor subunit gp130 SE Nicholson, D De Souza, LJ Fabri, J Corbin, TA Willson, JG Zhang, ... Proceedings of the National Academy of Sciences 97 (12), 6493-6498, 2000 | 599 | 2000 |
| Mutational analyses of the SOCS proteins suggest a dual domain requirement but distinct mechanisms for inhibition of LIF and IL‐6 signal transduction SE Nicholson, TA Willson, A Farley, R Starr, JG Zhang, M Baca, ... The EMBO journal, 1999 | 547 | 1999 |
| Biology and significance of the JAK/STAT signalling pathways H Kiu, SE Nicholson Growth factors 30 (2), 88-106, 2012 | 519 | 2012 |
| CIS is a potent checkpoint in NK cell–mediated tumor immunity RB Delconte, TB Kolesnik, LF Dagley, J Rautela, W Shi, EM Putz, ... Nature immunology 17 (7), 816-824, 2016 | 335 | 2016 |
| Familial autoinflammation with neutrophilic dermatosis reveals a regulatory mechanism of pyrin activation SL Masters, V Lagou, I Jéru, PJ Baker, L Van Eyck, DA Parry, D Lawless, ... Science translational medicine 8 (332), 332ra45-332ra45, 2016 | 303 | 2016 |
| Tyrosine kinase JAK1 is associated with the granulocyte-colony-stimulating factor receptor and both become tyrosine-phosphorylated after receptor activation. SE Nicholson, AC Oates, AG Harpur, A Ziemiecki, AF Wilks, JE Layton Proceedings of the National Academy of Sciences 91 (8), 2985-2988, 1994 | 275 | 1994 |
| Suppression of cytokine signaling: the SOCS perspective EM Linossi, JJ Babon, DJ Hilton, SE Nicholson Cytokine & growth factor reviews 24 (3), 241-248, 2013 | 221 | 2013 |
| Suppressor of cytokine signaling (SOCS) 1 inhibits type I interferon (IFN) signaling via the interferon α receptor (IFNAR1)-associated tyrosine kinase Tyk2 RAR Piganis, NA De Weerd, JA Gould, CW Schindler, A Mansell, ... Journal of biological chemistry 286 (39), 33811-33818, 2011 | 217 | 2011 |
| The SOCS box of suppressor of cytokine signaling-1 is important for inhibition of cytokine action in vivo JG Zhang, D Metcalf, S Rakar, M Asimakis, CJ Greenhalgh, TA Willson, ... Proceedings of the National Academy of Sciences 98 (23), 13261-13265, 2001 | 206 | 2001 |
| The structure of SOCS3 reveals the basis of the extended SH2 domain function and identifies an unstructured insertion that regulates stability JJ Babon, EJ McManus, S Yao, DP DeSouza, LA Mielke, NS Sprigg, ... Molecular cell 22 (2), 205-216, 2006 | 197 | 2006 |
| Distinct regions of the granulocyte colony-stimulating factor receptor are required for tyrosine phosphorylation of the signaling molecules JAK2, Stat3, and p42, p44MAPK SE Nicholson, U Novak, SF Ziegler, JE Layton | 194 | 1995 |
| The SOCS proteins: a new family of negative regulators of signal transduction SE Nicholson, DJ Hilton Journal of leukocyte biology 63 (6), 665-668, 1998 | 183 | 1998 |
| SOCS-6 binds to insulin receptor substrate 4, and mice lacking the SOCS-6 gene exhibit mild growth retardation DL Krebs, RT Uren, D Metcalf, S Rakar, JG Zhang, R Starr, DP De Souza, ... Molecular and cellular biology, 2002 | 176 | 2002 |
| Innate immunodeficiency following genetic ablation of Mcl1 in natural killer cells P Sathe, RB Delconte, F Souza-Fonseca-Guimaraes, C Seillet, M Chopin, ... Nature communications 5 (1), 4539, 2014 | 173 | 2014 |
| The IL-4/IL-13/Stat6 signalling pathway promotes luminal mammary epithelial cell development WT Khaled, EKC Read, SE Nicholson, FO Baxter, AJ Brennan, PJ Came, ... Oxford University Press for The Company of Biologists Limited 134 (15), 2739 …, 2007 | 163 | 2007 |
| Suppressors of cytokine signaling (SOCS): negative regulators of signal transduction WS Alexander, R Starr, D Metcalf, SE Nicholson, A Farley, AG Elefanty, ... Journal of leukocyte biology 66 (4), 588-592, 1999 | 161 | 1999 |
