27-Hydroxycholesterol links hypercholesterolemia and breast cancer pathophysiology ER Nelson, SE Wardell, JS Jasper, S Park, S Suchindran, MK Howe, ... Science 342 (6162), 1094-1098, 2013 | 832 | 2013 |
A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages Y Yu, JC Fuscoe, C Zhao, C Guo, M Jia, T Qing, DI Bannon, L Lancashire, ... Nature communications 5 (1), 1-11, 2014 | 362 | 2014 |
Systematic identification of signaling pathways with potential to confer anticancer drug resistance CA Martz, KA Ottina, KR Singleton, JS Jasper, SE Wardell, ... Science signaling 7 (357), ra121-ra121, 2014 | 219 | 2014 |
The metabolic regulator ERRα, a downstream target of HER2/IGF-1R, as a therapeutic target in breast cancer C Chang, D Kazmin, JS Jasper, R Kunder, WJ Zuercher, DP McDonnell Cancer cell 20 (4), 500-510, 2011 | 164 | 2011 |
Evaluating the analytical validity of circulating tumor DNA sequencing assays for precision oncology IW Deveson, B Gong, K Lai, JS LoCoco, TA Richmond, J Schageman, ... Nature biotechnology 39 (9), 1115-1128, 2021 | 148 | 2021 |
ERRα-regulated lactate metabolism contributes to resistance to targeted therapies in breast cancer S Park, CY Chang, R Safi, X Liu, R Baldi, JS Jasper, GR Anderson, T Liu, ... Cell reports 15 (2), 323-335, 2016 | 135 | 2016 |
Obesity, cholesterol metabolism, and breast cancer pathogenesis DP McDonnell, S Park, MT Goulet, J Jasper, SE Wardell, C Chang, ... Cancer research 74 (18), 4976-4982, 2014 | 124 | 2014 |
CYP27A1 loss dysregulates cholesterol homeostasis in prostate cancer MA Alfaqih, ER Nelson, W Liu, R Safi, JS Jasper, E Macias, J Geradts, ... Cancer research 77 (7), 1662-1673, 2017 | 94 | 2017 |
Lysine-specific histone demethylase 1 inhibitors control breast cancer proliferation in ERα-dependent and-independent manners JA Pollock, MD Larrea, JS Jasper, DP McDonnell, DG McCafferty ACS chemical biology 7 (7), 1221-1231, 2012 | 91 | 2012 |
Toward best practice in cancer mutation detection with whole-genome and whole-exome sequencing W Xiao, L Ren, Z Chen, LT Fang, Y Zhao, J Lack, M Guan, B Zhu, ... Nature biotechnology 39 (9), 1141-1150, 2021 | 79 | 2021 |
MiR-148a functions to suppress metastasis and serves as a prognostic indicator in triple-negative breast cancer X Xu, Y Zhang, J Jasper, E Lykken, PB Alexander, GJ Markowitz, ... Oncotarget 7 (15), 20381, 2016 | 71 | 2016 |
ABL kinases promote breast cancer osteolytic metastasis by modulating tumor-bone interactions through TAZ and STAT5 signaling J Wang, C Rouse, JS Jasper, AM Pendergast Science signaling 9 (413), ra12-ra12, 2016 | 60 | 2016 |
The lineage determining factor GRHL2 collaborates with FOXA1 to establish a targetable pathway in endocrine therapy-resistant breast cancer KJ Cocce, JS Jasper, TK Desautels, L Everett, S Wardell, T Westerling, ... Cell reports 29 (4), 889-903. e10, 2019 | 51 | 2019 |
Delineation of a foxa1/erα/agr2 regulatory loop that is dysregulated in endocrine therapy–resistant breast cancer TM Wright, SE Wardell, JS Jasper, JP Stice, R Safi, ER Nelson, ... Molecular cancer research 12 (12), 1829-1839, 2014 | 47 | 2014 |
Effect of aerobic training on the host systemic milieu in patients with solid tumours: an exploratory correlative study OK Glass, BA Inman, G Broadwater, KS Courneya, JR Mackey, S Goruk, ... British journal of cancer 112 (5), 825-831, 2015 | 39 | 2015 |
Distinct receptor tyrosine kinase subsets mediate anti-HER2 drug resistance in breast cancer PB Alexander, R Chen, C Gong, L Yuan, JS Jasper, Y Ding, GJ Markowitz, ... Journal of Biological Chemistry 292 (2), 748-759, 2017 | 38 | 2017 |
ELF3 is a repressor of androgen receptor action in prostate cancer cells A Shatnawi, JD Norris, C Chaveroux, JS Jasper, AB Sherk, DP McDonnell, ... Oncogene 33 (7), 862-871, 2014 | 34 | 2014 |
A verified genomic reference sample for assessing performance of cancer panels detecting small variants of low allele frequency W Jones, B Gong, N Novoradovskaya, D Li, R Kusko, TA Richmond, ... Genome biology 22, 1-38, 2021 | 30 | 2021 |
Impact of RNA-seq data analysis algorithms on gene expression estimation and downstream prediction L Tong, PY Wu, JH Phan, HR Hassazadeh, W Tong, MD Wang Scientific reports 10 (1), 17925, 2020 | 26 | 2020 |
Cross-oncopanel study reveals high sensitivity and accuracy with overall analytical performance depending on genomic regions B Gong, D Li, R Kusko, N Novoradovskaya, Y Zhang, S Wang, ... Genome biology 22, 1-23, 2021 | 21 | 2021 |