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Alex K. Shalek
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Highly parallel genome-wide expression profiling of individual cells using nanoliter droplets
EZ Macosko, A Basu, R Satija, J Nemesh, K Shekhar, M Goldman, I Tirosh, ...
Cell 161 (5), 1202-1214, 2015
66912015
Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma
AP Patel, I Tirosh, JJ Trombetta, AK Shalek, SM Gillespie, H Wakimoto, ...
Science 344 (6190), 1396-1401, 2014
42652014
Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq
I Tirosh, B Izar, SM Prakadan, MH Wadsworth, D Treacy, JJ Trombetta, ...
Science 352 (6282), 189-196, 2016
37882016
SARS-CoV-2 receptor ACE2 is an interferon-stimulated gene in human airway epithelial cells and is detected in specific cell subsets across tissues
CGK Ziegler, SJ Allon, SK Nyquist, IM Mbano, VN Miao, CN Tzouanas, ...
Cell 181 (5), 1016-1035. e19, 2020
23222020
MAST: a flexible statistical framework for assessing transcriptional changes and characterizing heterogeneity in single-cell RNA sequencing data
G Finak, A McDavid, M Yajima, J Deng, V Gersuk, AK Shalek, CK Slichter, ...
Genome biology 16, 1-13, 2015
22752015
The human cell atlas
A Regev, SA Teichmann, ES Lander, I Amit, C Benoist, E Birney, ...
elife 6, e27041, 2017
19422017
Single-cell transcriptomics reveals bimodality in expression and splicing in immune cells
AK Shalek, R Satija, X Adiconis, RS Gertner, JT Gaublomme, ...
Nature 498 (7453), 236-240, 2013
13352013
Single-cell RNA-seq reveals dynamic paracrine control of cellular variation
AK Shalek, R Satija, J Shuga, JJ Trombetta, D Gennert, D Lu, P Chen, ...
Nature 510 (7505), 363-369, 2014
10392014
A cancer cell program promotes T cell exclusion and resistance to checkpoint blockade
L Jerby-Arnon, P Shah, MS Cuoco, C Rodman, MJ Su, JC Melms, ...
Cell 175 (4), 984-997. e24, 2018
9972018
Reconstructing and reprogramming the tumor-propagating potential of glioblastoma stem-like cells
ML Suvà, E Rheinbay, SM Gillespie, AP Patel, H Wakimoto, SD Rabkin, ...
Cell 157 (3), 580-594, 2014
9172014
Intra-and inter-cellular rewiring of the human colon during ulcerative colitis
CS Smillie, M Biton, J Ordovas-Montanes, KM Sullivan, G Burgin, ...
Cell 178 (3), 714-730. e22, 2019
8732019
Seq-Well: portable, low-cost RNA sequencing of single cells at high throughput
TM Gierahn, MH Wadsworth, TK Hughes, BD Bryson, A Butler, R Satija, ...
Nature methods 14 (4), 395-398, 2017
8382017
Dynamic regulatory network controlling TH17 cell differentiation
N Yosef, AK Shalek, JT Gaublomme, H Jin, Y Lee, A Awasthi, C Wu, ...
Nature 496 (7446), 461-468, 2013
7632013
Single-cell RNA-seq reveals AML hierarchies relevant to disease progression and immunity
P van Galen, V Hovestadt, MH Wadsworth II, TK Hughes, GK Griffin, ...
Cell 176 (6), 1265-1281. e24, 2019
7272019
Vertical nanowire electrode arrays as a scalable platform for intracellular interfacing to neuronal circuits
JT Robinson, M Jorgolli, AK Shalek, MH Yoon, RS Gertner, H Park
Nature nanotechnology 7 (3), 180-184, 2012
6322012
Vertical silicon nanowires as a universal platform for delivering biomolecules into living cells
AK Shalek, JT Robinson, ES Karp, JS Lee, DR Ahn, MH Yoon, A Sutton, ...
Proceedings of the National Academy of Sciences 107 (5), 1870-1875, 2010
6292010
Whole-exome sequencing of circulating tumor cells provides a window into metastatic prostate cancer
JG Lohr, VA Adalsteinsson, K Cibulskis, AD Choudhury, M Rosenberg, ...
Nature biotechnology 32 (5), 479-484, 2014
5992014
Systematic comparison of single-cell and single-nucleus RNA-sequencing methods
J Ding, X Adiconis, SK Simmons, MS Kowalczyk, CC Hession, ...
Nature biotechnology 38 (6), 737-746, 2020
5892020
COVID-19 tissue atlases reveal SARS-CoV-2 pathology and cellular targets
TM Delorey, CGK Ziegler, G Heimberg, R Normand, Y Yang, ...
Nature 595 (7865), 107-113, 2021
5862021
Single-cell genomics unveils critical regulators of Th17 cell pathogenicity
JT Gaublomme, N Yosef, Y Lee, RS Gertner, LV Yang, C Wu, PP Pandolfi, ...
Cell 163 (6), 1400-1412, 2015
5812015
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