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Guilhian Leipnitz
Guilhian Leipnitz
E-mail confirmado em ufrgs.br
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α-Ketoisocaproic acid and leucine provoke mitochondrial bioenergetic dysfunction in rat brain
AU Amaral, G Leipnitz, CG Fernandes, B Seminotti, PF Schuck, M Wajner
Brain research 1324, 75-84, 2010
1102010
Inhibition of cytochrome c oxidase activity in rat cerebral cortex and human skeletal muscle by D-2-hydroxyglutaric acid in vitro
CG Da Silva, CAJ Ribeiro, G Leipnitz, CS Dutra-Filho, ÂTS Wyse, ...
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1586 (1), 81-91, 2002
982002
In vitro evidence for an antioxidant role of 3-hydroxykynurenine and 3-hydroxyanthranilic acid in the brain
G Leipnitz, C Schumacher, KB Dalcin, K Scussiato, A Solano, C Funchal, ...
Neurochemistry international 50 (1), 83-94, 2007
972007
Evidences that maternal swimming exercise improves antioxidant defenses and induces mitochondrial biogenesis in the brain of young Wistar rats
TB Marcelino, A Longoni, KY Kudo, V Stone, A Rech, AM De Assis, ...
Neuroscience 246, 28-39, 2013
822013
Oxidative stress-mediated inhibition of brain creatine kinase activity by methylmercury
V Glaser, G Leipnitz, MR Straliotto, J Oliveira, VV dos Santos, ...
Neurotoxicology 31 (5), 454-460, 2010
732010
Induction of oxidative stress by L‐2‐hydroxyglutaric acid in rat brain
A Latini, K Scussiato, R Borba Rosa, G Leipnitz, S Llesuy, A Belló‐Klein, ...
Journal of neuroscience research 74 (1), 103-110, 2003
722003
Experimental evidence that phenylalanine provokes oxidative stress in hippocampus and cerebral cortex of developing rats
CG Fernandes, G Leipnitz, B Seminotti, AU Amaral, Â Zanatta, CR Vargas, ...
Cellular and molecular neurobiology 30, 317-326, 2010
652010
3-Hydroxyglutaric acid moderately impairs energy metabolism in brain of young rats
A Latini, M Rodriguez, RB Rosa, K Scussiato, G Leipnitz, DR De Assis, ...
Neuroscience 135 (1), 111-120, 2005
642005
Quinolinic acid reduces the antioxidant defenses in cerebral cortex of young rats
G Leipnitz, C Schumacher, K Scussiato, KB Dalcin, CMD Wannmacher, ...
International Journal of Developmental Neuroscience 23 (8), 695-701, 2005
632005
Promotion of oxidative stress by 3‐hydroxyglutaric acid in rat striatum
A Latini, K Scussiato, G Leipnitz, CS Dutra‐Filho, M Wajner
Journal of Inherited Metabolic Disease: Official Journal of the Society for …, 2005
622005
Evaluation of mitochondrial bioenergetics, dynamics, endoplasmic reticulum-mitochondria crosstalk, and reactive oxygen species in fibroblasts from patients with complex I …
G Leipnitz, AW Mohsen, A Karunanidhi, B Seminotti, VY Roginskaya, ...
Scientific reports 8 (1), 1165, 2018
612018
Experimental evidence that methylmalonic acid provokes oxidative damage and compromises antioxidant defenses in nerve terminal and striatum of young rats
CG Fernandes, CG Borges, B Seminotti, AU Amaral, LA Knebel, P Eichler, ...
Cellular and molecular neurobiology 31, 775-785, 2011
582011
Antioxidant properties of mesenchymal stem cells against oxidative stress in a murine model of colitis
F da Costa Gonçalves, M Grings, NS Nunes, FO Pinto, TNA Garcez, ...
Biotechnology letters 39, 613-622, 2017
572017
Inhibition of creatine kinase activity from rat cerebral cortex by D-2-hydroxyglutaric acid in vitro
CG Da Silva, ARF Bueno, PF Schuck, G Leipnitz, CAJ Ribeiro, RB Rosa, ...
Neurochemistry international 44 (1), 45-52, 2004
562004
Mitochondrial energetics is impaired in very long-chain acyl-CoA dehydrogenase deficiency and can be rescued by treatment with mitochondria-targeted electron scavengers
B Seminotti, G Leipnitz, A Karunanidhi, C Kochersperger, VY Roginskaya, ...
Human molecular genetics 28 (6), 928-941, 2019
522019
Inhibition of Creatine Kinase Activity in Vitro by Ethylmalonic Acid in Cerebral Cortex of Young Rats
PF Schuck, G Leipnitz, CAJ Ribeiro, KB Dalcin, DR Assis, AG Barschak, ...
Neurochemical research 27, 1633-1639, 2002
522002
Bezafibrate prevents mitochondrial dysfunction, antioxidant system disturbance, glial reactivity and neuronal damage induced by sulfite administration in striatum of rats …
M Grings, AP Moura, B Parmeggiani, JT Pletsch, GMF Cardoso, ...
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1863 (9 …, 2017
492017
Physical exercise during pregnancy prevents cognitive impairment induced by amyloid-β in adult offspring rats
CP Klein, JB Hoppe, AB Saccomori, BG Dos Santos, JP Sagini, ...
Molecular neurobiology 56, 2022-2038, 2019
462019
Oxidative stress, disrupted energy metabolism, and altered signaling pathways in glutaryl-CoA dehydrogenase knockout mice: potential implications of quinolinic acid toxicity in …
B Seminotti, AU Amaral, RT Ribeiro, MDN Rodrigues, AL Colín-González, ...
Molecular neurobiology 53, 6459-6475, 2016
432016
Disturbance of brain energy and redox homeostasis provoked by sulfite and thiosulfate: potential pathomechanisms involved in the neuropathology of sulfite oxidase deficiency
M Grings, AP Moura, B Parmeggiani, GF Marcowich, AU Amaral, ...
Gene 531 (2), 191-198, 2013
422013
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