| Functional profiling of a Plasmodium genome reveals an abundance of essential genes E Bushell, AR Gomes, T Sanderson, B Anar, G Girling, C Herd, T Metcalf, ... Cell 170 (2), 260-272. e8, 2017 | 491 | 2017 |
| Chloroquine transport via the malaria parasite’s chloroquine resistance transporter RE Martin, RV Marchetti, AI Cowan, SM Howitt, S Bröer, K Kirk science 325 (5948), 1680-1682, 2009 | 406 | 2009 |
| Defining the role of PfCRT in Plasmodium falciparum chloroquine resistance PG Bray, RE Martin, L Tilley, SA Ward, K Kirk, DA Fidock Molecular microbiology 56 (2), 323-333, 2005 | 291 | 2005 |
| The malaria parasite's chloroquine resistance transporter is a member of the drug/metabolite transporter superfamily RE Martin, K Kirk Molecular biology and evolution 21 (10), 1938-1949, 2004 | 279 | 2004 |
| Globally prevalent PfMDR1 mutations modulate Plasmodium falciparum susceptibility to artemisinin-based combination therapies MI Veiga, SK Dhingra, PP Henrich, J Straimer, N Gnädig, AC Uhlemann, ... Nature communications 7 (1), 11553, 2016 | 264 | 2016 |
| The 'permeome' of the malaria parasite: an overview of the membrane transport proteins of Plasmodium falciparum RE Martin, RI Henry, JL Abbey, JD Clements, K Kirk Genome biology 6, 1-22, 2005 | 212 | 2005 |
| Transport of the essential nutrient isoleucine in human erythrocytes infected with the malaria parasite Plasmodium falciparum RE Martin, K Kirk Blood 109 (5), 2217-2224, 2007 | 155 | 2007 |
| Sodium-dependent uptake of inorganic phosphate by the intracellular malaria parasite KJ Saliba, RE Martin, A Bröer, RI Henry, C Siobhan McCarthy, MJ Downie, ... Nature 443 (7111), 582-585, 2006 | 119 | 2006 |
| Membrane transport proteins of the malaria parasite RE Martin, H Ginsburg, K Kirk Molecular microbiology 74 (3), 519-528, 2009 | 104 | 2009 |
| Know your enemy: understanding the role of PfCRT in drug resistance could lead to new antimalarial tactics RL Summers, MN Nash, RE Martin Cellular and Molecular Life Sciences 69, 1967-1995, 2012 | 96 | 2012 |
| Mutations in the Plasmodium falciparum chloroquine resistance transporter, PfCRT, enlarge the parasite’s food vacuole and alter drug sensitivities S Pulcini, HM Staines, AH Lee, SH Shafik, G Bouyer, CM Moore, ... Scientific reports 5 (1), 14552, 2015 | 93 | 2015 |
| Diverse mutational pathways converge on saturable chloroquine transport via the malaria parasite’s chloroquine resistance transporter RL Summers, A Dave, TJ Dolstra, S Bellanca, RV Marchetti, MN Nash, ... Proceedings of the National Academy of Sciences 111 (17), E1759-E1767, 2014 | 77 | 2014 |
| Quinoline antimalarials containing a dibemethin group are active against chloroquinone-resistant Plasmodium falciparum and inhibit chloroquine transport via the P. falciparum … VK Zishiri, MC Joshi, R Hunter, K Chibale, PJ Smith, RL Summers, ... Journal of medicinal chemistry 54 (19), 6956-6968, 2011 | 77 | 2011 |
| A lactate and formate transporter in the intraerythrocytic malaria parasite, Plasmodium falciparum RV Marchetti, AM Lehane, SH Shafik, M Winterberg, RE Martin, K Kirk Nature communications 6 (1), 6721, 2015 | 76 | 2015 |
| Mimicking the intramolecular hydrogen bond: synthesis, biological evaluation, and molecular modeling of benzoxazines and quinazolines as potential antimalarial agents S Gemma, C Camodeca, M Brindisi, S Brogi, G Kukreja, S Kunjir, ... Journal of medicinal chemistry 55 (23), 10387-10404, 2012 | 71 | 2012 |
| The natural function of the malaria parasite’s chloroquine resistance transporter SH Shafik, SA Cobbold, K Barkat, SN Richards, NS Lancaster, M Llinás, ... Nature communications 11 (1), 3922, 2020 | 68 | 2020 |
| Optimization of 4-aminoquinoline/clotrimazole-based hybrid antimalarials: Further structure–activity relationships, in vivo studies, and preliminary toxicity profiling S Gemma, C Camodeca, S Sanna Coccone, BP Joshi, M Bernetti, ... Journal of medicinal chemistry 55 (15), 6948-6967, 2012 | 52 | 2012 |
| The malaria parasite's lactate transporter PfFNT is the target of antiplasmodial compounds identified in whole cell phenotypic screens SV Hapuarachchi, SA Cobbold, SH Shafik, ASM Dennis, MJ McConville, ... PLoS pathogens 13 (2), e1006180, 2017 | 51 | 2017 |
| Multiple drugs compete for transport via the Plasmodium falciparum chloroquine resistance transporter at distinct but interdependent sites S Bellanca, RL Summers, M Meyrath, A Dave, MN Nash, M Dittmer, ... Journal of Biological Chemistry 289 (52), 36336-36351, 2014 | 48 | 2014 |
| The transportome of the malaria parasite RE Martin Biological Reviews 95 (2), 305-332, 2020 | 47 | 2020 |
Robert L SummersHarvard T.H. Chan School of Public HealthVerified email at hsph.harvard.edu
