DNA repair pathways and cisplatin resistance: an intimate relationship CRR Rocha, MM Silva, A Quinet, JB Cabral-Neto, CFM Menck Clinics 73, e478s, 2018 | 403 | 2018 |
Glutathione depletion sensitizes cisplatin-and temozolomide-resistant glioma cells in vitro and in vivo CRR Rocha, CCM Garcia, DB Vieira, A Quinet, LC de Andrade-Lima, ... Cell death & disease 5 (10), e1505-e1505, 2014 | 124 | 2014 |
NRF2 and glutathione are key resistance mediators to temozolomide in glioma and melanoma cells CRR Rocha, GS Kajitani, A Quinet, RS Fortunato, CFM Menck Oncotarget 7 (30), 48081, 2016 | 112 | 2016 |
The role of DNA repair in the pluripotency and differentiation of human stem cells CRR Rocha, LK Lerner, OK Okamoto, MC Marchetto, CFM Menck Mutation Research/Reviews in Mutation Research 752 (1), 25-35, 2013 | 106 | 2013 |
The balance between NRF2/GSH antioxidant mediated pathway and DNA repair modulates cisplatin resistance in lung cancer cells MM Silva, CRR Rocha, GS Kinker, AL Pelegrini, CFM Menck Scientific reports 9 (1), 17639, 2019 | 97 | 2019 |
Gap-filling and bypass at the replication fork are both active mechanisms for tolerance of low-dose ultraviolet-induced DNA damage in the human genome A Quinet, AT Vessoni, CRR Rocha, V Gottifredi, D Biard, A Sarasin, ... DNA repair 14, 27-38, 2014 | 76 | 2014 |
The role of chaperone-mediated autophagy in cell cycle control and its implications in cancer M Andrade-Tomaz, I de Souza, C Ribeiro Reily Rocha, ... Cells 9 (9), 2140, 2020 | 58 | 2020 |
Predominant role of DNA polymerase eta and p53-dependent translesion synthesis in the survival of ultraviolet-irradiated human cells LK Lerner, G Francisco, DT Soltys, CRR Rocha, A Quinet, AT Vessoni, ... Nucleic acids research 45 (3), 1270-1280, 2017 | 58 | 2017 |
Overexpression of KLC2 due to a homozygous deletion in the non-coding region causes SPOAN syndrome US Melo, LI Macedo-Souza, T Figueiredo, AR Muotri, JG Gleeson, ... Human molecular genetics 24 (24), 6877-6885, 2015 | 56 | 2015 |
ATR mediates cisplatin resistance in 3D-cultured breast cancer cells via translesion DNA synthesis modulation LR Gomes, CRR Rocha, DJ Martins, APZP Fiore, GS Kinker, ... Cell death & disease 10 (6), 459, 2019 | 51 | 2019 |
Novel XPG (ERCC5) Mutations Affect DNA Repair and Cell Survival after Ultraviolet but not Oxidative Stress DT Soltys, CRR Rocha, LK Lerner, TA de Souza, V Munford, F Cabral, ... Human mutation 34 (3), 481-489, 2013 | 50 | 2013 |
Nucleotide excision repair activity on DNA damage induced by photoactivated methylene blue CM Berra, CS de Oliveira, CCM Garcia, CRR Rocha, LK Lerner, ... Free Radical Biology and Medicine 61, 343-356, 2013 | 47 | 2013 |
DNA damage and its cellular response in mother and fetus exposed to hyperglycemic environment JB Moreli, JH Santos, CR Rocha, DC Damasceno, G Morceli, MV Rudge, ... BioMed research international 2014, 2014 | 46 | 2014 |
Mutation in PNKP presenting initially as axonal Charcot-Marie-Tooth disease JL Pedroso, CRR Rocha, LI Macedo-Souza, V De Mario, W Marques Jr, ... Neurology: Genetics 1 (4), e30, 2015 | 36 | 2015 |
Direct participation of DNA in the formation of singlet oxygen and base damage under UVA irradiation T Yagura, AP Schuch, CCM Garcia, CRR Rocha, NC Moreno, JPF Angeli, ... Free Radical Biology and Medicine 108, 86-93, 2017 | 34 | 2017 |
High levels of NRF2 sensitize temozolomide-resistant glioblastoma cells to ferroptosis via ABCC1/MRP1 upregulation I De Souza, LKS Monteiro, CB Guedes, MM Silva, M Andrade-Tomaz, ... Cell Death & Disease 13 (7), 591, 2022 | 33 | 2022 |
Revealing Temozolomide Resistance Mechanisms via Genome-Wide CRISPR Libraries CRR Rocha, AR Rocha, MM Silva, LR Gomes, MT Latancia, ... Cells 9 (12), 2573, 2020 | 33 | 2020 |
The key role of UVA-light induced oxidative stress in human Xeroderma Pigmentosum Variant cells NC Moreno, CCM Garcia, V Munford, CRR Rocha, AL Pelegrini, ... Free Radical Biology and Medicine 131, 432-442, 2019 | 30 | 2019 |
Chloroquine-induced glioma cells death is associated with mitochondrial membrane potential loss, but not oxidative stress AT Vessoni, A Quinet, LC de Andrade-Lima, DJ Martins, CCM Garcia, ... Free Radical Biology and Medicine 90, 91-100, 2016 | 29 | 2016 |
Hyperglycemia differentially affects maternal and fetal DNA integrity and DNA damage response JB Moreli, JH Santos, AR Lorenzon-Ojea, S Corrêa-Silva, RS Fortunato, ... International journal of biological sciences 12 (4), 466, 2016 | 28 | 2016 |