Haematopoietic stem and progenitor cells from human pluripotent stem cells R Sugimura, DK Jha, A Han, C Soria-Valles, EL Da Rocha, YF Lu, ... Nature 545 (7655), 432-438, 2017 | 493 | 2017 |
Noncanonical Wnt signaling maintains hematopoietic stem cells in the niche R Sugimura, XC He, A Venkatraman, F Arai, A Box, C Semerad, JS Haug, ... Cell 150 (2), 351-365, 2012 | 324 | 2012 |
Maternal imprinting at the H19–Igf2 locus maintains adult haematopoietic stem cell quiescence A Venkatraman, XC He, JL Thorvaldsen, R Sugimura, JM Perry, F Tao, ... Nature 500 (7462), 345-349, 2013 | 305 | 2013 |
Noncanonical Wnt signaling in vertebrate development, stem cells, and diseases R Sugimura, L Li Birth Defects Research Part C: Embryo Today: Reviews 90 (4), 243-256, 2010 | 243 | 2010 |
Cooperation between both Wnt/β-catenin and PTEN/PI3K/Akt signaling promotes primitive hematopoietic stem cell self-renewal and expansion JM Perry, XC He, R Sugimura, JC Grindley, JS Haug, S Ding, L Li Genes & development 25 (18), 1928-1942, 2011 | 205 | 2011 |
Shifting in balance between osteogenesis and adipogenesis substantially influences hematopoiesis R Sugimura, L Li Journal of molecular cell biology 2 (2), 61-62, 2010 | 45 | 2010 |
Recent advances and future prospects in immune checkpoint (ICI)-based combination therapy for advanced HCC Y Dong, JSL Wong, R Sugimura, KO Lam, B Li, GGW Kwok, R Leung, ... Cancers 13 (8), 1949, 2021 | 35 | 2021 |
Bioengineering hematopoietic stem cell niche toward regenerative medicine R Sugimura Advanced drug delivery reviews 99, 212-220, 2016 | 26 | 2016 |
Hemogenic endothelium differentiation from human pluripotent stem cells in a feeder-and xeno-free defined condition R Ohta, R Sugimura, A Niwa, MK Saito JoVE (Journal of Visualized Experiments), e59823, 2019 | 16 | 2019 |
ZFP281-BRCA2 prevents R-loop accumulation during DNA replication Y Wang, B Ma, X Liu, G Gao, Z Che, M Fan, S Meng, X Zhao, R Sugimura, ... Nature communications 13 (1), 3493, 2022 | 14 | 2022 |
The significance and application of vascular niche in the development and maintenance of hematopoietic stem cells R Sugimura International journal of hematology 107 (6), 642-645, 2018 | 9 | 2018 |
Integrating spatial and single-cell transcriptomics data using deep generative models with SpatialScope X Wan, J Xiao, SST Tam, M Cai, R Sugimura, Y Wang, X Wan, Z Lin, ... Nature Communications 14 (1), 7848, 2023 | 8 | 2023 |
Organoid-based single-cell spatiotemporal gene expression landscape of human embryonic development and hematopoiesis Y Chao, Y Xiang, J Xiao, W Zheng, MR Ebrahimkhani, C Yang, AR Wu, ... Signal transduction and targeted therapy 8 (1), 230, 2023 | 8 | 2023 |
Give Them Vasculature and Immune Cells: How to Fill the Gap of Organoids S Yip, N Wang, R Sugimura Cells Tissues Organs 212 (5), 369-382, 2023 | 7 | 2023 |
IPSC-derived CAR-NK cells for cancer immunotherapy X Lin, Y Sun, X Dong, Z Liu, R Sugimura, G Xie Biomedicine & Pharmacotherapy 165, 115123, 2023 | 7 | 2023 |
Biomimetic aorta-gonad-Mesonephros-on-a-Chip to study human developmental hematopoiesis R Sugimura, R Ohta, C Mori, A Li, T Mano, E Sano, K Kosugi, T Nakahata, ... Biomedical microdevices 22, 1-6, 2020 | 7 | 2020 |
Homing and migration assays of hematopoietic stem/progenitor cells XC He, Z Li, R Sugimura, J Ross, M Zhao, L Li Hematopoietic Stem Cell Protocols, 279-284, 2014 | 7 | 2014 |
The tumor microenvironment reprograms immune cells H Cao, S Gao, R Jogani, R Sugimura Cellular Reprogramming 24 (6), 343-352, 2022 | 6 | 2022 |
Deciphering innate immune cell-tumor microenvironment crosstalk at a single-cell level R Sugimura, Y Chao Frontiers in Cell and Developmental Biology 10, 803947, 2022 | 5 | 2022 |
T, NK, then macrophages: Recent advances and challenges in adaptive immunotherapy from human pluripotent stem cells S Hang, N Wang, R Sugimura Differentiation 130, 51-57, 2023 | 4 | 2023 |