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jlenia guarnerio
jlenia guarnerio
assistant professor, Cedars-Sinai, UCLA
E-mail confirmado em cshs.org - Página inicial
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Oncogenic role of fusion-circRNAs derived from cancer-associated chromosomal translocations
J Guarnerio, M Bezzi, JC Jeong, SV Paffenholz, K Berry, MM Naldini, ...
Cell 165 (2), 289-302, 2016
7202016
Cancer-associated PTEN mutants act in a dominant-negative manner to suppress PTEN protein function
A Papa, L Wan, M Bonora, L Salmena, MS Song, RM Hobbs, A Lunardi, ...
Cell 157 (3), 595-610, 2014
3072014
Active Pin1 is a key target of all-trans retinoic acid in acute promyelocytic leukemia and breast cancer
S Wei, S Kozono, L Kats, M Nechama, W Li, J Guarnerio, M Luo, MH You, ...
Nature medicine 21 (5), 457-466, 2015
2632015
PHD3 loss in cancer enables metabolic reliance on fatty acid oxidation via deactivation of ACC2
NJ German, H Yoon, RZ Yusuf, JP Murphy, LWS Finley, G Laurent, ...
Molecular cell 63 (6), 1006-1020, 2016
1502016
Intragenic antagonistic roles of protein and circRNA in tumorigenesis
J Guarnerio, Y Zhang, G Cheloni, R Panella, J Mae Katon, M Simpson, ...
Cell research 29 (8), 628-640, 2019
1322019
Commensal bacteria and fungi differentially regulate tumor responses to radiation therapy
SL Shiao, KM Kershaw, JJ Limon, S You, J Yoon, EY Ko, J Guarnerio, ...
Cancer cell 39 (9), 1202-1213. e6, 2021
1312021
Role of LRF/Pokemon in lineage fate decisions
A Lunardi, J Guarnerio, G Wang, T Maeda, PP Pandolfi
Blood, The Journal of the American Society of Hematology 121 (15), 2845-2853, 2013
712013
A circular twist on microRNA regulation
M Bezzi, J Guarnerio, PP Pandolfi
Cell Research 27 (12), 1401-1402, 2017
502017
Suppression of CHK1 by ETS Family Members Promotes DNA Damage Response Bypass and Tumorigenesis
A Lunardi, S Varmeh, M Chen, R Taulli, J Guarnerio, U Ala, N Seitzer, ...
Cancer discovery 5 (5), 550-563, 2015
452015
HIF factors cooperate with PML‐RAR α to promote acute promyelocytic leukemia progression and relapse
N Coltella, S Percio, R Valsecchi, R Cuttano, J Guarnerio, M Ponzoni, ...
EMBO molecular medicine 6 (5), 640-650, 2014
432014
Vulnerabilities in mIDH2 AML confer sensitivity to APL-like targeted combination therapy
V Mugoni, R Panella, G Cheloni, M Chen, O Pozdnyakova, D Stroopinsky, ...
Cell research 29 (6), 446-459, 2019
402019
Bone marrow endosteal mesenchymal progenitors depend on HIF factors for maintenance and regulation of hematopoiesis
J Guarnerio, N Coltella, U Ala, G Tonon, PP Pandolfi, R Bernardi
Stem cell reports 2 (6), 794-809, 2014
342014
Synthetic CD4+ T Cell–Targeted Antigen-Presenting Cells Elicit Protective Antitumor Responses
S Caserta, P Alessi, J Guarnerio, V Basso, A Mondino
Cancer research 68 (8), 3010-3018, 2008
342008
A non-cell-autonomous role for Pml in the maintenance of leukemia from the niche
J Guarnerio, LM Mendez, N Asada, AV Menon, J Fung, K Berry, ...
Nature communications 9 (1), 66, 2018
312018
A genetic platform to model sarcomagenesis from primary adult mesenchymal stem cells
J Guarnerio, L Riccardi, R Taulli, T Maeda, G Wang, RM Hobbs, MS Song, ...
Cancer discovery 5 (4), 396-409, 2015
262015
Cell death-induced immunogenicity enhances chemoimmunotherapeutic response by converting immune-excluded into T-cell inflamed bladder tumors
F Nikolos, K Hayashi, XP Hoi, ME Alonzo, Q Mo, A Kasabyan, H Furuya, ...
Nature Communications 13 (1), 1487, 2022
212022
Single-cell RNA-seq of a soft-tissue sarcoma model reveals the critical role of tumor-expressed MIF in shaping macrophage heterogeneity
FHG Tessaro, EY Ko, M De Simone, R Piras, MT Broz, HS Goodridge, ...
Cell reports 39 (12), 2022
182022
circCsnk1g3-and circAnkib1-regulated interferon responses in sarcoma promote tumorigenesis by shaping the immune microenvironment
R Piras, EY Ko, C Barrett, M De Simone, X Lin, MT Broz, FHG Tessaro, ...
Nature Communications 13 (1), 7243, 2022
82022
CircFISH: a novel method for the simultaneous imaging of linear and circular RNAs
A Koppula, A Abdelgawad, J Guarnerio, M Batish, V Parashar
Cancers 14 (2), 428, 2022
82022
Antigen-Experienced CD4+ T Cells Limit Naïve T-Cell Priming in Response to Therapeutic Vaccination In vivo
C Schiering, J Guarnerio, V Basso, L Muzio, A Mondino
Cancer research 70 (15), 6161-6170, 2010
82010
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Artigos 1–20