Priming approaches to improve the efficacy of mesenchymal stromal cell-based therapies NC Noronha, A Mizukami, C Caliári-Oliveira, JG Cominal, JLM Rocha, ... Stem cell research & therapy 10, 1-21, 2019 | 508 | 2019 |
Human cells: new platform for recombinant therapeutic protein production K Swiech, V Picanço-Castro, DT Covas Protein expression and purification 84 (1), 147-153, 2012 | 226 | 2012 |
Comparative analysis of 3D bladder tumor spheroids obtained by forced floating and hanging drop methods for drug screening RLF Amaral, M Miranda, PD Marcato, K Swiech Frontiers in physiology 8, 284532, 2017 | 173 | 2017 |
Mesenchymal stromal cells: from discovery to manufacturing and commercialization A Mizukami, K Swiech Stem cells international 2018, 2018 | 150 | 2018 |
Stirred tank bioreactor culture combined with serum‐/xenogeneic‐free culture medium enables an efficient expansion of umbilical cord‐derived mesenchymal stem/stromal cells A Mizukami, A Fernandes‐Platzgummer, JG Carmelo, K Swiech, ... Biotechnology journal 11 (8), 1048-1059, 2016 | 75 | 2016 |
Combining xanthan and chitosan membranes to multipotent mesenchymal stromal cells as bioactive dressings for dermo-epidermal wounds MZ Bellini, C Caliari-Oliveira, A Mizukami, K Swiech, DT Covas, ... Journal of biomaterials applications 29 (8), 1155-1166, 2015 | 69 | 2015 |
Cell spheroids as a versatile research platform: Formation mechanisms, high throughput production, characterization and applications MC Decarli, R Amaral, DP Dos Santos, LB Tofani, E Katayama, ... Biofabrication 13 (3), 032002, 2021 | 68 | 2021 |
Growth and functional harvesting of human mesenchymal stromal cells cultured on a microcarrier‐based system SR Caruso, MD Orellana, A Mizukami, TR Fernandes, AM Fontes, ... Biotechnology progress 30 (4), 889-895, 2014 | 65 | 2014 |
Technologies for large-scale umbilical cord-derived MSC expansion: Experimental performance and cost of goods analysis A Mizukami, TDP Chilima, MD Orellana, MA Neto, DT Covas, SS Farid, ... Biochemical Engineering Journal 135, 36-48, 2018 | 61 | 2018 |
Expansion strategies for human mesenchymal stromal cells culture under xeno‐free conditions PA Tozetti, SR Caruso, A Mizukami, TR Fernandes, FB da Silva, F Traina, ... Biotechnology Progress 33 (5), 1358-1367, 2017 | 60 | 2017 |
Development, characterization and biological in vitro assays of paclitaxel-loaded PCL polymeric nanoparticles JP Abriata, RC Turatti, MT Luiz, GL Raspantini, LB Tofani, RLF do Amaral, ... Materials Science and Engineering: C 96, 347-355, 2019 | 58 | 2019 |
Transient transfection of serum-free suspension HEK 293 cell culture for efficient production of human rFVIII K Swiech, A Kamen, S Ansorge, Y Durocher, V Picanço-Castro, ... BMC biotechnology 11, 1-10, 2011 | 57 | 2011 |
In vitro evaluation of folate-modified PLGA nanoparticles containing paclitaxel for ovarian cancer therapy MT Luiz, JP Abriata, GL Raspantini, LB Tofani, F Fumagalli, SMG de Melo, ... Materials Science and Engineering: C 105, 110038, 2019 | 47 | 2019 |
Efficient expansion of mesenchymal stromal cells in a disposable fixed bed culture system A Mizukami, MD Orellana, SR Caruso, K de Lima Prata, DT Covas, ... Biotechnology progress 29 (2), 568-572, 2013 | 42 | 2013 |
Production of recombinant therapeutic proteins in human cells: current achievements and future perspectives V Picanço-Castro, R Tage Biaggio, D Tadeu Cova, K Swiech Protein and Peptide Letters 20 (12), 1373-1381, 2013 | 40 | 2013 |
Production of recombinant coagulation factors: are humans the best host cells? K Swiech, V Picanço-Castro, DT Covas Bioengineered 8 (5), 462-470, 2017 | 39 | 2017 |
A fully-closed and automated hollow fiber bioreactor for clinical-grade manufacturing of human mesenchymal stem/stromal cells A Mizukami, MS de Abreu Neto, F Moreira, A Fernandes-Platzgummer, ... Stem cell reviews and reports 14, 141-143, 2018 | 36 | 2018 |
Mesenchymal stromal cells in viral infections: implications for COVID-19 JLM Rocha, WCF de Oliveira, NC Noronha, NCD Dos Santos, DT Covas, ... Stem cell reviews and reports 17, 71-93, 2021 | 33 | 2021 |
Establishment of a simple and efficient platform for car-t cell generation and expansion: from lentiviral production to in vivo studies V Picanço-Castro, PD Moço, A Mizukami, LD Vaz, MSF Pereira, ... Hematology, transfusion and cell therapy 42 (2), 150-158, 2020 | 30 | 2020 |
Characterization of human AB serum for mesenchymal stromal cell expansion VTM Dos Santos, A Mizukami, MD Orellana, SR Caruso, FB da Silva, ... Transfusion Medicine and Hemotherapy 44 (1), 11-21, 2017 | 30 | 2017 |