Christian Schlein

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Jörg HeerenProfessor für Biochemie, UKEE-mail confirmado em hamburg.de
Alexander BarteltProfessor of Cardiovascular Metabolism at Ludwig-Maximilians-University MunichE-mail confirmado em med.uni-muenchen.de
Alexander W. FischerProgram Lead at E-therapeuticsE-mail confirmado em etherapeutics.co.uk
Anna WorthmannPhD, Junior Research Group Leader, University Medical Center Hamburg-EppendorfE-mail confirmado em uke.de
Markus HeinePostDoc, University Medical Center Hamburg-Eppendorf, Department of Biochemistry and Molecular Cell BiologyE-mail confirmado em uke.de
Yu-Hua TsengJoslin Diabetes Center, Harvard Medical SchoolE-mail confirmado em joslin.harvard.edu
Louis HavekesTNO Metabolic Health Research and Prof. Leiden University Medical Center, Leiden, the NetherlandsE-mail confirmado em tno.nl
Prof. Dr. Markus FischerUniversity of Hamburg, Hamburg School of Food ScienceE-mail confirmado em hsfs.org
Morten LundhGubraE-mail confirmado em gubra.dk
Farnaz ShamsiNew York UniversityE-mail confirmado em nyu.edu
Francis J. MayCleveland Clinic Lerner College of MedicineE-mail confirmado em ccf.org
Sander KooijmanLeiden University Medical CenterE-mail confirmado em lumc.nl
Saswata TalukdarCardio Metabolic Diseases, Merck Research Labs, South San FranciscoE-mail confirmado em merck.com
Andre FrankeProfessor for Molecular Medicine, Christian-Albrechts-University of KielE-mail confirmado em mucosa.de
Malte Christoph RühlemannIKMB, Kiel UniversityE-mail confirmado em ikmb.uni-kiel.de
Holger FröhlichHead of AI & Data Science Group & Deputy Head of Department of Bioinformatics at Fraunhofer SCAIE-mail confirmado em scai.fraunhofer.de
Yong ChenUCSFE-mail confirmado em ucsf.edu
Scott WidenmaierUniversity of SaskatchewanE-mail confirmado em usask.ca
Gunes Parlakgul, M.D.Adjunct Assistant Professor, University of California, BerkeleyE-mail confirmado em berkeley.edu
Renata L GoncalvesHarvard School of Public HealthE-mail confirmado em hsph.harvard.edu

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Christian Schlein

MD, PhD. Principal investigator at University Medical Center Hamburg Eppendorf

E-mail confirmado em uke.de

Lipid metabolism Liver and Adipose tissue biology Genetics


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Brown fat activation reduces hypercholesterolaemia and protects from atherosclerosis development JFP Berbée, MR Boon, PPSJ Khedoe, A Bartelt, C Schlein, A Worthmann, ... Nature communications 6 (1), 6356, 2015	475	2015
The cold-induced lipokine 12, 13-diHOME promotes fatty acid transport into brown adipose tissue MD Lynes, LO Leiria, M Lundh, A Bartelt, F Shamsi, TL Huang, ... Nature medicine 23 (5), 631-637, 2017	374	2017
FGF21 lowers plasma triglycerides by accelerating lipoprotein catabolism in white and brown adipose tissues C Schlein, S Talukdar, M Heine, AW Fischer, LM Krott, SK Nilsson, ... Cell metabolism 23 (3), 441-453, 2016	256	2016
Cold-induced conversion of cholesterol to bile acids in mice shapes the gut microbiome and promotes adaptive thermogenesis A Worthmann, C John, MC Rühlemann, M Baguhl, FA Heinsen, ... Nature medicine 23 (7), 839-849, 2017	254	2017
Exosomal microRNA miR-92a concentration in serum reflects human brown fat activity Y Chen, JJ Buyel, MJW Hanssen, F Siegel, R Pan, J Naumann, M Schell, ... Nature communications 7 (1), 11420, 2016	167	2016
Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity A Bartelt, SB Widenmaier, C Schlein, K Johann, RLS Goncalves, K Eguchi, ... Nature medicine 24 (3), 292-303, 2018	165	2018
Thermogenic adipocytes promote HDL turnover and reverse cholesterol transport A Bartelt, C John, N Schaltenberg, JFP Berbée, A Worthmann, ... Nature communications 8 (1), 15010, 2017	149	2017
Lipolysis triggers a systemic insulin response essential for efficient energy replenishment of activated brown adipose tissue in mice M Heine, AW Fischer, C Schlein, C Jung, LG Straub, K Gottschling, ... Cell metabolism 28 (4), 644-655. e4, 2018	144	2018
Apoptotic brown adipocytes enhance energy expenditure via extracellular inosine B Niemann, S Haufs-Brusberg, L Puetz, M Feickert, MY Jaeckstein, ... Nature 609 (7926), 361-368, 2022	66	2022
Intact innervation is essential for diet-induced recruitment of brown adipose tissue AW Fischer, C Schlein, B Cannon, J Heeren, J Nedergaard American Journal of Physiology-Endocrinology and Metabolism 316 (3), E487-E503, 2019	65	2019
Lysosomal lipoprotein processing in endothelial cells stimulates adipose tissue thermogenic adaptation AW Fischer, MY Jaeckstein, K Gottschling, M Heine, F Sass, N Mangels, ... Cell metabolism 33 (3), 547-564. e7, 2021	47	2021
Endogenous fatty acid synthesis drives brown adipose tissue involution C Schlein, AW Fischer, F Sass, A Worthmann, K Tödter, MY Jaeckstein, ... Cell reports 34 (2), 2021	42	2021
Homozygosity for a partial deletion of apoprotein AV signal peptide results in intracellular missorting of the protein and chylomicronemia in a breast-fed infant K Albers, C Schlein, K Wenner, P Lohse, A Bartelt, J Heeren, R Santer, ... Atherosclerosis 233 (1), 97-103, 2014	33	2014
Course of HEV viremia and anti-HEV IgM/IgG response in asymptomatic blood donors C Kraef, C Schlein, J Hiller, D Westhölter, U Denzer, T Horvatits, S Peine, ... Journal of Clinical Virology 105, 26-30, 2018	27	2018
FoxO transcription factors are required for hepatic HDL cholesterol clearance SX Lee, M Heine, C Schlein, R Ramakrishnan, J Liu, G Belnavis, I Haimi, ... The Journal of clinical investigation 128 (4), 1615-1626, 2018	26	2018
Genetic dissection of tissue-specific apolipoprotein E function for hypercholesterolemia and diet-induced obesity T Wagner, A Bartelt, C Schlein, J Heeren PloS one 10 (12), e0145102, 2015	23	2015
TFEB deficiency attenuates mitochondrial degradation upon brown adipose tissue whitening at thermoneutrality F Sass, C Schlein, MY Jaeckstein, P Pertzborn, M Schweizer, T Schinke, ... Molecular Metabolism 47, 101173, 2021	19	2021
Thermoneutrality-induced macrophage accumulation in brown adipose tissue does not impair the tissue’s competence for cold-induced thermogenic recruitment AW Fischer, JMA De Jong, F Sass, C Schlein, J Heeren, N Petrovic Frontiers in endocrinology 11, 568682, 2020	16	2020
Brown adipose tissue lipoprotein and glucose disposal is not determined by thermogenesis in uncoupling protein 1-deficient mice AW Fischer, J Behrens, F Sass, C Schlein, M Heine, P Pertzborn, ... Journal of Lipid Research 61 (11), 1377-1389, 2020	15	2020
PID1 regulates insulin-dependent glucose uptake by controlling intracellular sorting of GLUT4-storage vesicles AW Fischer, K Albers, C Schlein, F Sass, LM Krott, H Schmale, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1865 (6 …, 2019	14	2019

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