| Mechanism for alternating access in neurotransmitter transporters LR Forrest, YW Zhang, MT Jacobs, J Gesmonde, L Xie, BH Honig, ... Proceedings of the National Academy of Sciences 105 (30), 10338, 2008 | 405 | 2008 |
| Outcomes for out-of-hospital cardiac arrests across 7 countries in Asia: The Pan Asian Resuscitation Outcomes Study (PAROS) MEH Ong, S Do Shin, NNA De Souza, H Tanaka, T Nishiuchi, KJ Song, ... Resuscitation 96, 100-108, 2015 | 377 | 2015 |
| Drug discovery using chemical systems biology: identification of the protein-ligand binding network to explain the side effects of CETP inhibitors L Xie, J Li, L Xie, PE Bourne PLoS computational biology 5 (5), e1000387, 2009 | 319 | 2009 |
| Drug off-target effects predicted using structural analysis in the context of a metabolic network model RL Chang, L Xie, L Xie, PE Bourne, BØ Palsson PLoS Computational Biology 6 (9), e1000938, 2010 | 242 | 2010 |
| Novel Computational Approaches to Polypharmacology as a Means to Define Responses to Individual Drugs PE Bourne, L Xie, L Xie Annual Review of Pharmacology and Toxicology 52 (1), 2011 | 222 | 2011 |
| Positronium formation as a probe of polymer surfaces and thin films L Xie, GB DeMaggio, WE Frieze, J DeVries, DW Gidley, HA Hristov, ... Physical review letters 74 (24), 4947, 1995 | 205 | 1995 |
| Autotetraploids and genetic mapping using common AFLP markers: the R2 allele conferring resistance to Phytophthora infestans mapped on potato chromosome 4 X Li, HJ Van Eck, J Rouppe Van Der Voort, DJ Huigen, P Stam, ... Theoretical and Applied Genetics 96, 1121-1128, 1998 | 199 | 1998 |
| Drug discovery using chemical systems biology: weak inhibition of multiple kinases may contribute to the anti-cancer effect of nelfinavir L Xie, T Evangelidis, L Xie, PE Bourne PLoS computational biology 7 (4), e1002037, 2011 | 187 | 2011 |
| Joint analysis of three genome-wide association studies of esophageal squamous cell carcinoma in Chinese populations C Wu, Z Wang, X Song, XS Feng, CC Abnet, J He, N Hu, XB Zuo, W Tan, ... Nature genetics 46 (9), 1001-1006, 2014 | 172 | 2014 |
| Structure-based systems biology for analyzing off-target binding L Xie, L Xie, PE Bourne Current opinion in structural biology, 2011 | 171 | 2011 |
| Serial measures of plasma homocyst (e) ine after acute myocardial infarction W Egerton, J Silberberg, R Crooks, C Ray, L Xie, N Dudman The American journal of cardiology 77 (9), 759-761, 1996 | 167 | 1996 |
| Measurement of hole volume in amorphous polymers using positron spectroscopy HA Hristov, B Bolan, AF Yee, L Xie, DW Gidley Macromolecules 29 (26), 8507-8516, 1996 | 148 | 1996 |
| Dectin-1 is inducible and plays a crucial role in Aspergillus-induced innate immune responses in human bronchial epithelial cells WK Sun, X Lu, X Li, QY Sun, X Su, Y Song, HM Sun, Y Shi European Journal of Clinical Microbiology & Infectious Diseases 31, 2755-2764, 2012 | 136 | 2012 |
| Quantifying reproducibility in computational biology: the case of the tuberculosis drugome D Garijo, S Kinnings, L Xie, L Xie, Y Zhang, PE Bourne, Y Gil PloS one 8 (11), e80278, 2013 | 132 | 2013 |
| Phosphoenolpyruvate Carboxylase in Arabidopsis Leaves Plays a Crucial Role in Carbon and Nitrogen Metabolism J Shi, K Yi, Y Liu, L Xie, Z Zhou, Y Chen, Z Hu, T Zheng, R Liu, Y Chen, ... Plant physiology 167 (3), 671-681, 2015 | 128 | 2015 |
| A unified statistical model to support local sequence order independent similarity searching for ligand-binding sites and its application to genome-based drug discovery L Xie, L Xie, PE Bourne Bioinformatics 25 (12), i305-i312, 2009 | 122 | 2009 |
| A calibrated measurement of the atomic weight of carbon 张青莲， 李文军 科学通报: 英文版, 290-296, 1990 | 118 | 1990 |
| The Mycobacterium tuberculosis Drugome and Its Polypharmacological Implications SL Kinnings, L Xie, KH Fung, RM Jackson, L Xie, PE Bourne PLoS computational biology 6 (11), e1000976, 2010 | 117 | 2010 |
| Edible film coating to minimize eggshell breakage and reduce post‐wash bacterial contamination measured by dye penetration in eggs L Xie, NS Hettiarachchy, ZY Ju, J Meullenet, H Wang, MF Slavik, ... Journal of Food Science 67 (1), 280-284, 2002 | 114 | 2002 |
| Adapting the nudged elastic band method for determining minimum-energy paths of chemical reactions in enzymes L Xie, H Liu, W Yang The Journal of chemical physics 120 (17), 8039-8052, 2004 | 93 | 2004 |
