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Sean J Miller
Sean J Miller
Yale University School of Medicine
E-mail confirmado em yale.edu
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The C9orf72 repeat expansion disrupts nucleocytoplasmic transport
K Zhang, CJ Donnelly, AR Haeusler, JC Grima, JB Machamer, ...
Nature 525 (7567), 56-61, 2015
10172015
Combined adult neurogenesis and BDNF mimic exercise effects on cognition in an Alzheimer’s mouse model
SH Choi, E Bylykbashi, ZK Chatila, SW Lee, B Pulli, GD Clemenson, ...
Science 361 (6406), eaan8821, 2018
6622018
Tau protein disrupts nucleocytoplasmic transport in Alzheimer’s disease
B Eftekharzadeh, JG Daigle, LE Kapinos, A Coyne, J Schiantarelli, ...
Neuron 99 (5), 925-940. e7, 2018
3612018
Astrocyte heterogeneity in the adult central nervous system
SJ Miller
Frontiers in cellular neuroscience 12, 401, 2018
2042018
Characterization of a Drosophila Alzheimer's disease model: pharmacological rescue of cognitive defects
R Chakraborty, V Vepuri, SD Mhatre, BE Paddock, S Miller, SJ Michelson, ...
PloS one 6 (6), e20799, 2011
1632011
Molecularly defined cortical astroglia subpopulation modulates neurons via secretion of Norrin
SJ Miller, T Philips, N Kim, R Dastgheyb, Z Chen, YC Hsieh, JG Daigle, ...
Nature neuroscience 22 (5), 741-752, 2019
682019
Deep convolutional neural networks with ensemble learning and generative adversarial networks for Alzheimer’s disease image data classification
R Logan, BG Williams, M Ferreira da Silva, A Indani, N Schcolnicov, ...
Frontiers in aging neuroscience 13, 720226, 2021
362021
Soluble gamma-secretase modulators attenuate Alzheimer's β-amyloid pathology and induce conformational changes in presenilin 1
F Raven, JF Ward, KM Zoltowska, Y Wan, E Bylykbashi, SJ Miller, X Shen, ...
EBioMedicine 24, 93-101, 2017
312017
Tau protein disrupts nucleocytoplasmic transport in Alzheimer’s disease
B Eftekharzadeh, JG Daigle, LE Kapinos, A Coyne, J Schiantarelli, ...
Neuron 101 (2), 349, 2019
242019
Astroglia in thick tissue with super resolution and cellular reconstruction
SJ Miller, JD Rothstein
PloS one 11 (8), e0160391, 2016
212016
Upregulation of Alzheimer’s disease amyloid-β protein precursor in astrocytes both in vitro and in vivo
Y Liang, F Raven, JF Ward, S Zhen, S Zhang, H Sun, SJ Miller, SH Choi, ...
Journal of Alzheimer's Disease 76 (3), 1071-1082, 2020
192020
Cortical astroglia undergo transcriptomic dysregulation in the G93A SOD1 ALS mouse model
SJ Miller, JC Glatzer, Y Hsieh, JD Rothstein
Journal of neurogenetics 32 (4), 322-335, 2018
192018
Astroglial transcriptome dysregulation in early disease of an ALS mutant SOD1 mouse model
SJ Miller, P Zhang, J Glatzer, JD Rothstein
Journal of neurogenetics 31 (1-2), 37-48, 2017
162017
Neuroglial senescence, α-synucleinopathy, and the therapeutic potential of senolytics in Parkinson’s disease
SJ Miller, CE Campbell, HA Jimenez-Corea, GH Wu, R Logan
Frontiers in Neuroscience 16, 824191, 2022
152022
Cyclopamine modulates γ-secretase-mediated cleavage of amyloid precursor protein by altering its subcellular trafficking and lysosomal degradation
AG Vorobyeva, R Lee, S Miller, C Longen, M Sharoni, PJ Kandelwal, ...
Journal of Biological Chemistry 289 (48), 33258-33274, 2014
142014
Induced adult neurogenesis plus BDNF Mimicks the effects of exercise on cognition in an Alzheimer’s mouse model
SH Choi, E Bylykbashi, ZK Chatila, SW Lee, B Pulli, GD Clemenson, ...
Science (New York, NY) 361 (6406), 2018
72018
Novel genetic signatures associated with sporadic amyotrophic lateral sclerosis
R Logan, J Dubel-Haag, N Schcolnicov, SJ Miller
Frontiers in Genetics 13, 851496, 2022
52022
Calcineurin overexpression regulates APP metabolism
S Utreja, S J Miller, A Saunders
Advances in Alzheimer's Disease 2 (03), 109-116, 2013
32013
Mechanisms of Action in Neurodegenerative Proteinopathies
SJ Miller, S Wray, R Sattler, C Zhang
Frontiers in Neuroscience 16, 968994, 2022
22022
The future of artificial intelligence for Alzheimer’s disease diagnostics
R Logan, SS Zerbey, SJ Miller
Advances in Alzheimer's Disease 10 (4), 53-59, 2021
22021
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Artigos 1–20