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Sarah van Veen
Sarah van Veen
Verified email at kuleuven.be
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Year
ATP13A2 deficiency disrupts lysosomal polyamine export
S van Veen, S Martin, C Van den Haute, V Benoy, J Lyons, R Vanhoutte, ...
Nature 578 (7795), 419-424, 2020
2172020
Loss-of-function mutations in the ATP13A2/PARK9 gene cause complicated hereditary spastic paraplegia (SPG78)
A Estrada-Cuzcano, S Martin, T Chamova, M Synofzik, D Timmann, ...
Brain 140 (2), 287-305, 2017
1672017
Cellular function and pathological role of ATP13A2 and related P-type transport ATPases in Parkinson's disease and other neurological disorders
S van Veen, DM Sørensen, T Holemans, HW Holen, MG Palmgren, ...
Frontiers in molecular neuroscience 7, 48, 2014
942014
A lipid switch unlocks Parkinson’s disease-associated ATP13A2
T Holemans, DM Sørensen, S van Veen, S Martin, D Hermans, ...
Proceedings of the National Academy of Sciences 112 (29), 9040-9045, 2015
932015
ATP13A2-mediated endo-lysosomal polyamine export counters mitochondrial oxidative stress
S Vrijsen, L Besora-Casals, S van Veen, J Zielich, C Van den Haute, ...
Proceedings of the National Academy of Sciences 117 (49), 31198-31207, 2020
662020
ATP13A2/PARK9 regulates endo-/lysosomal cargo sorting and proteostasis through a novel PI (3, 5) P2-mediated scaffolding function
S Demirsoy, S Martin, S Motamedi, S Van Veen, T Holemans, ...
Human Molecular Genetics 26 (9), 1656-1669, 2017
662017
Parkinson disease related ATP13A2 evolved early in animal evolution
DM Sørensen, T Holemans, S van Veen, S Martin, T Arslan, ...
PloS one 13 (3), e0193228, 2018
532018
Mutated ATP10B increases Parkinson’s disease risk by compromising lysosomal glucosylceramide export
S Martin, S Smolders, C Van den Haute, B Heeman, S van Veen, ...
Acta Neuropathologica 139, 1001-1024, 2020
502020
Protection against mitochondrial and metal toxicity depends on functional lipid binding sites in ATP13A2
S Martin, S van Veen, T Holemans, S Demirsoy, C van den Haute, ...
Parkinson's disease 2016, 2016
292016
ATP13A2 regulates cellular α-synuclein multimerization, membrane association, and externalization
J Si, C Van den Haute, E Lobbestael, S Martin, S van Veen, ...
International Journal of Molecular Sciences 22 (5), 2689, 2021
202021
Clickable polyamine derivatives as chemical probes for the polyamine transport system
R Vanhoutte, JP Kahler, S Martin, S van Veen, SHL Verhelst
ChemBioChem 19 (9), 907-911, 2018
162018
P5B-ATPases in the mammalian polyamine transport system and their role in disease
M Azfar, S van Veen, M Houdou, NN Hamouda, J Eggermont, ...
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1869 (12), 119354, 2022
112022
Polyamine transport assay using reconstituted yeast membranes
S Van Veen, S Martin, M Schuermans, P Vangheluwe
Bio-protocol 11 (2), e3888-e3888, 2021
22021
ATP13A2/PARK9 regulates endo-/lysosomal cargo sorting and proteostasis through a novel PI (3, 5) P2-mediated scaffolding function (vol 26, pg 1656, 2017)
S Demirsoy, S Martin, S Motamedi, S van Veen, T Holemans, ...
HUMAN MOLECULAR GENETICS, 2024
2024
ATP13A4, a novel polyamine transporter implicated in breast cancer
S van Veen, A Kourti, E Ausloos, J Van Asselberghs, C Van den Haute, ...
Gordon Research Conference-Polyamines, Location: Waterville Valley, NH …, 2023
2023
ATP13A4 upregulation drives the elevated polyamine transport system in the breast cancer cell line MCF7
S Van Veen, A Kourti, E Ausloos, J Van Asselberghs, C Van den Haute, ...
Biomolecules 13 (6), 918, 2023
2023
Connecting polyamine transport in astrocytes to neurodevelopmental disorders via ATP13A4
S van Veen, C Van den Haute, V Baekelandt, J Eggermont, M Holt, ...
GliaCamp, Location: Chapel Hill, North Carolina, US, 2023
2023
A novel class of polyamine transporters in health and disease
S van Veen, N Hamouda, M Azfar, S Vrijsen, J Si, C Van den Haute, ...
6th International Conference on Polyamines, Location: Tivoli, Rome, Italy, 2022
2022
Quest for the transported substrate of ATP13A4, a putative polyamine transporter linked to neurodevelopmental disorders
S van Veen, V Baekelandt, J Eggermont, M Holt, P Vangheluwe
6th International Conference on Polyamines, Location: Tivoli, Rome, Italy, 2022
2022
Compound heterozygous mutations in ATP10B increase Parkinson's disease risk by compromising lysosomal glucosylceramide export
S Smolders, S Martin, C Van Den Haute, B Heeman, S Van Veen, ...
European Journal Of Neurology 27, 72-72, 2020
2020
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