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Pratik Aryal
Pratik Aryal
Beth Israel Deaconess Medical Center/Harvard Medical School
E-mail confirmado em bidmc.harvard.edu
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RBP4 activates antigen-presenting cells, leading to adipose tissue inflammation and systemic insulin resistance
PM Moraes-Vieira, MM Yore, PM Dwyer, I Syed, P Aryal, BB Kahn
Cell metabolism 19 (3), 512-526, 2014
2732014
Retinol-binding protein 4 inhibits insulin signaling in adipocytes by inducing proinflammatory cytokines in macrophages through a c-Jun N-terminal kinase-and toll-like receptor …
J Norseen, T Hosooka, A Hammarstedt, MM Yore, S Kant, P Aryal, ...
Molecular and cellular biology 32 (10), 2010-2019, 2012
2642012
Palmitic acid hydroxystearic acids activate GPR40, which is involved in their beneficial effects on glucose homeostasis
I Syed, J Lee, PM Moraes-Vieira, CJ Donaldson, A Sontheimer, P Aryal, ...
Cell metabolism 27 (2), 419-427. e4, 2018
1582018
Liver retinol transporter and receptor for serum retinol-binding protein (RBP4)
P Alapatt, F Guo, SM Komanetsky, S Wang, J Cai, A Sargsyan, ER Díaz, ...
Journal of Biological Chemistry 288 (2), 1250-1265, 2013
1582013
Absence of carbohydrate response element binding protein in adipocytes causes systemic insulin resistance and impairs glucose transport
A Vijayakumar, P Aryal, J Wen, I Syed, RP Vazirani, PM Moraes-Vieira, ...
Cell reports 21 (4), 1021-1035, 2017
1352017
Branched fatty acid esters of hydroxy fatty acids (FAHFAs) protect against colitis by regulating gut innate and adaptive immune responses
J Lee, PM Moraes-Vieira, A Castoldi, P Aryal, EU Yee, C Vickers, ...
Journal of biological chemistry 291 (42), 22207-22217, 2016
1232016
Obesity-linked PPARγ S273 phosphorylation promotes insulin resistance through growth differentiation factor 3
JA Hall, D Ramachandran, HC Roh, JR DiSpirito, T Belchior, PJH Zushin, ...
Cell metabolism 32 (4), 665-675. e6, 2020
662020
A postsynaptic AMPK→ p21-activated kinase pathway drives fasting-induced synaptic plasticity in AgRP neurons
D Kong, Y Dagon, JN Campbell, Y Guo, Z Yang, X Yi, P Aryal, ...
Neuron 91 (1), 25-33, 2016
662016
Antigen presentation and T-cell activation are critical for RBP4-induced insulin resistance
PM Moraes-Vieira, A Castoldi, P Aryal, K Wellenstein, OD Peroni, ...
Diabetes 65 (5), 1317-1327, 2016
622016
Retinol binding protein 4 primes the NLRP3 inflammasome by signaling through Toll-like receptors 2 and 4
PM Moraes-Vieira, MM Yore, A Sontheimer-Phelps, A Castoldi, J Norseen, ...
Proceedings of the National Academy of Sciences 117 (49), 31309-31318, 2020
552020
RBP4 increases lipolysis in human adipocytes and is associated with increased lipolysis and hepatic insulin resistance in obese women
M Kilicarslan, BA de Weijer, KS Sjödin, P Aryal, KW Ter Horst, H Cakir, ...
The FASEB Journal 34 (5), 6099, 2020
482020
Distinct biological activities of isomers from several families of branched fatty acid esters of hydroxy fatty acids (FAHFAs)
P Aryal, I Syed, J Lee, R Patel, AT Nelson, D Siegel, A Saghatelian, ...
Journal of lipid research 62, 2021
382021
High-throughput mediation analysis of human proteome and metabolome identifies mediators of post-bariatric surgical diabetes control
JM Dreyfuss, Y Yuchi, X Dong, V Efthymiou, H Pan, DC Simonson, ...
Nature communications 12 (1), 6951, 2021
142021
RBP4 inhibits insulin signaling in adipocytes by inducing pro-inflammatory cytokines in macrophages through a JNK-and TLR4-dependent and retinol-independent mechanism
J Norseen, T Hosooka, A Hammarstedt, MM Yore, S Kant, P Aryal, ...
Diabetes 61, A85-A85, 2012
42012
RBP4 inhibits insulin signaling in adipocytes by inducing pro-inflammatory cytokines in macrophages through a JNK-and TLR4-dependent and retinol-independent mechanism
J Norseen, T Hosooka, A Hammarstedt, MM Yore, S Kant, P Aryal, ...
Diabetes 61, A85-A85, 2012
42012
Doxorubicin Resistance in a Small Cell Lung Cancer Cell Line Can be Abolished by SiRNA Down-regulation of Cox 1
P Aryal
Ball State University, 2007
22007
Retinol-binding protein 4 (RBP4) signals through TLR2 and TLR4/MD2
MM Yore, P Aryal, BB Kahn
Diabetes 61, A423-A424, 2012
12012
Sero-prevalence of Newcastle disease virus (NDV) specific antibody in chicken.
P Aryal, KM Hossain, MM Ahasan, KMD Islam, MM Billah, ME Islam, ...
12003
Novel mediation analysis of human plasma proteome and metabolome reveals mediators of improved glycemia after gastric bypass surgery
JM Dreyfuss, Y Yuchi, H Pan, X Dong, DC Simonson, A Vernon, P Aryal, ...
bioRxiv, 817494, 2019
2019
Integrative Analysis of Human Plasma Proteome/Metabolome Reveals Central Role for Phospholipid, Retinol, and Histidine Metabolism after Gastric Bypass
J Dreyfuss, Y Yuchi, H Pan, DC Simonson, AH Vernon, P Aryal, B Kahn, ...
Diabetes 67 (Supplement_1), 2018
2018
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