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Spiros Kotopoulis
Spiros Kotopoulis
Department of Clinical Medicine, University of Bergen
E-mail confirmado em uib.no
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A human clinical trial using ultrasound and microbubbles to enhance gemcitabine treatment of inoperable pancreatic cancer
G Dimcevski, S Kotopoulis, T Bjånes, D Hoem, J Schjøtt, BT Gjertsen, ...
Journal of Controlled Release 243, 172-181, 2016
4242016
Sonoporation: mechanistic insights and ongoing challenges for gene transfer
A Delalande, S Kotopoulis, M Postema, P Midoux, C Pichon
Gene 525 (2), 191-199, 2013
2352013
Treatment of human pancreatic cancer using combined ultrasound, microbubbles, and gemcitabine: a clinical case study
S Kotopoulis, G Dimcevski, O Helge Gilja, D Hoem, M Postema
Medical physics 40 (7), 072902, 2013
2332013
Sonoporation-enhanced chemotherapy significantly reduces primary tumour burden in an orthotopic pancreatic cancer xenograft
S Kotopoulis, A Delalande, M Popa, V Mamaeva, G Dimcevski, OH Gilja, ...
Molecular imaging and biology 16, 53-62, 2014
1432014
Microfoam formation in a capillary
S Kotopoulis, M Postema
Ultrasonics 50 (2), 260-268, 2010
742010
Sonoporation at a low mechanical index
A Delalande, S Kotopoulis, T Rovers, C Pichon, M Postema
Bubble Science, Engineering & Technology 3 (1), 3-12, 2011
672011
Ultrasound and microbubble-assisted gene delivery in Achilles tendons: long lasting gene expression and restoration of fibromodulin KO phenotype
A Delalande, A Bouakaz, G Renault, F Tabareau, S Kotopoulis, P Midoux, ...
Journal of Controlled Release 156 (2), 223-230, 2011
562011
Sonic cracking of blue-green algae
S Kotopoulis, A Schommartz, M Postema
Applied acoustics 70 (10), 1306-1312, 2009
512009
Laser-nucleated acoustic cavitation in focused ultrasound
B Gerold, S Kotopoulis, C McDougall, D McGloin, M Postema, P Prentice
Review of Scientific Instruments 82 (4), 2011
462011
Sonoporation with Acoustic Cluster Therapy (ACT®) induces transient tumour volume reduction in a subcutaneous xenograft model of pancreatic ductal adenocarcinoma
S Kotopoulis, E Stigen, M Popa, MM Safont, A Healey, S Kvåle, P Sontum, ...
Journal of Controlled Release 245, 70-80, 2017
392017
Acoustically active antibubbles
S Kotopoulis, K Johansen, OH Gilja, AT Poortinga, M Postema
Acta Physica Polonica A 127 (1), 99-102, 2015
362015
Intracellular cytidine deaminase regulates gemcitabine metabolism in pancreatic cancer cell lines
TK Bjånes, LP Jordheim, J Schjøtt, T Kamceva, E Cros-Perrial, A Langer, ...
Drug Metabolism and Disposition 48 (3), 153-158, 2020
322020
Sonoporation: why microbubbles create pores
M Postema, S Kotopoulis, A Delalande, OH Gilja
Ultraschall in der Medizin 33 (1), 97-98, 2012
322012
Ultrasound-and microbubble-assisted gemcitabine delivery to pancreatic cancer cells
T Bjånes, S Kotopoulis, ET Murvold, T Kamčeva, BT Gjertsen, OH Gilja, ...
Pharmaceutics 12 (2), 141, 2020
252020
Theranostic attributes of acoustic cluster therapy and its use for enhancing the effectiveness of liposomal doxorubicin treatment of human triple negative breast cancer in mice
N Bush, A Healey, A Shah, G Box, V Kirkin, S Eccles, PC Sontum, ...
Frontiers in Pharmacology 11, 75, 2020
242020
SonoVue® vs. Sonazoid™ vs. Optison™: Which Bubble Is Best for Low-Intensity Sonoporation of Pancreatic Ductal Adenocarcinoma?
S Kotopoulis, M Popa, M Mayoral Safont, E Murvold, R Haugse, A Langer, ...
Pharmaceutics 14 (1), 98, 2022
232022
Formulation and characterisation of drug-loaded antibubbles for image-guided and ultrasound-triggered drug delivery
S Kotopoulis, C Lam, R Haugse, S Snipstad, E Murvold, T Jouleh, S Berg, ...
Ultrasonics Sonochemistry 85, 105986, 2022
202022
Low-intensity sonoporation-induced intracellular signalling of pancreatic cancer cells, fibroblasts and endothelial cells
R Haugse, A Langer, ET Murvold, DE Costea, BT Gjertsen, OH Gilja, ...
Pharmaceutics 12 (11), 1058, 2020
192020
Sonoporation for augmenting chemotherapy of pancreatic ductal adenocarcinoma
J Castle, S Kotopoulis, F Forsberg
Drug Delivery Systems, 191-205, 2020
192020
Selecting the optimal parameters for sonoporation of pancreatic cancer in a pre-clinical model
CW Schultz, G Ruiz de Garibay, A Langer, JB Liu, T Dhir, C Leitch, ...
Cancer Biology & Therapy 22 (3), 204-215, 2021
172021
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