| Afferents to the orexin neurons of the rat brain K Yoshida, S McCormack, RA España, A Crocker, TE Scammell Journal of Comparative Neurology 494 (5), 845-861, 2006 | 681 | 2006 |
| Noradrenergic modulation of wakefulness/arousal CW Berridge, BE Schmeichel, RA España Sleep medicine reviews 16 (2), 187-197, 2012 | 370 | 2012 |
| Wake-promoting and sleep-suppressing actions of hypocretin (orexin): basal forebrain sites of action RA Espana, BA Baldo, AE Kelley, CW Berridge Neuroscience 106 (4), 699-715, 2001 | 367 | 2001 |
| Sleep neurobiology from a clinical perspective RA España, TE Scammell Sleep 34 (7), 845-858, 2011 | 362 | 2011 |
| Concomitant loss of dynorphin, NARP, and orexin in narcolepsy A Crocker, RA España, M Papadopoulou, CB Saper, J Faraco, T Sakurai, ... Neurology 65 (8), 1184-1188, 2005 | 336 | 2005 |
| Clozapine N-oxide administration produces behavioral effects in Long–Evans rats: implications for designing DREADD experiments DAA MacLaren, RW Browne, JK Shaw, SK Radhakrishnan, P Khare, ... eneuro 3 (5), 2016 | 319 | 2016 |
| Demon voltammetry and analysis software: analysis of cocaine-induced alterations in dopamine signaling using multiple kinetic measures JT Yorgason, RA España, SR Jones Journal of neuroscience methods 202 (2), 158-164, 2011 | 306 | 2011 |
| The hypocretin–orexin system regulates cocaine self‐administration via actions on the mesolimbic dopamine system RA España, EB Oleson, JL Locke, BR Brookshire, DCS Roberts, ... European Journal of Neuroscience 31 (2), 336-348, 2010 | 266 | 2010 |
| Sleep neurobiology for the clinician RA España, TE Scammell Sleep 27 (4), 811-820, 2004 | 225 | 2004 |
| Hypocretin/orexin in arousal and stress CW Berridge, RA España, NM Vittoz Brain research 1314, 91-102, 2010 | 208 | 2010 |
| Hypocretin 1/orexin A in the ventral tegmental area enhances dopamine responses to cocaine and promotes cocaine self-administration RA España, JR Melchior, DCS Roberts, SR Jones Psychopharmacology 214, 415-426, 2011 | 201 | 2011 |
| Dopamine transporters govern diurnal variation in extracellular dopamine tone MJ Ferris, RA España, JL Locke, JK Konstantopoulos, JH Rose, R Chen, ... Proceedings of the National Academy of Sciences 111 (26), E2751-E2759, 2014 | 192 | 2014 |
| Fos immunoreactivity in hypocretin-synthesizing and hypocretin-1 receptor-expressing neurons: effects of diurnal and nocturnal spontaneous waking, stress and hypocretin-1 … RA Espana, RJ Valentino, CW Berridge Neuroscience 121 (1), 201-217, 2003 | 158 | 2003 |
| Enduring increases in anxiety‐like behavior and rapid nucleus accumbens dopamine signaling in socially isolated rats JT Yorgason, RA España, JK Konstantopoulos, JL Weiner, SR Jones European Journal of Neuroscience 37 (6), 1022-1031, 2013 | 157 | 2013 |
| Organization of hypocretin/orexin efferents to locus coeruleus and basal forebrain arousal‐related structures RA España, KM Reis, RJ Valentino, CW Berridge Journal of comparative neurology 481 (2), 160-178, 2005 | 155 | 2005 |
| Running promotes wakefulness and increases cataplexy in orexin knockout mice RA España, SL McCormack, T Mochizuki, TE Scammell Sleep 30 (11), 1417-1425, 2007 | 127 | 2007 |
| Circadian-dependent and circadian-independent behavioral actions of hypocretin/orexin RA España, S Plahn, CW Berridge Brain research 943 (2), 224-236, 2002 | 123 | 2002 |
| Organization of noradrenergic efferents to arousal‐related basal forebrain structures RA España, CW Berridge Journal of comparative neurology 496 (5), 668-683, 2006 | 106 | 2006 |
| Chemogenetic manipulations of ventral tegmental area dopamine neurons reveal multifaceted roles in cocaine abuse SV Mahler, ZD Brodnik, BM Cox, WC Buchta, BS Bentzley, J Quintanilla, ... Journal of Neuroscience 39 (3), 503-518, 2019 | 93 | 2019 |
| Synergistic sedative effects of noradrenergic α1-and β-receptor blockade on forebrain electroencephalographic and behavioral indices CW Berridge, RA Espana Neuroscience 99 (3), 495-505, 2000 | 93 | 2000 |
