Alexander N Kapustin
Alexander N Kapustin
E-mail confirmado em astrazeneca.com
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Arterial calcification in chronic kidney disease: key roles for calcium and phosphate
CM Shanahan, MH Crouthamel, A Kapustin, CM Giachelli
Circulation research 109 (6), 697-711, 2011
6322011
Calcium regulates key components of vascular smooth muscle cell–derived matrix vesicles to enhance mineralization
AN Kapustin, JD Davies, JL Reynolds, R McNair, GT Jones, A Sidibe, ...
Circulation research 109 (1), e1-e12, 2011
2652011
Vascular smooth muscle cell calcification is mediated by regulated exosome secretion
AN Kapustin, MLL Chatrou, I Drozdov, Y Zheng, SM Davidson, D Soong, ...
Circulation research 116 (8), 1312-1323, 2015
2222015
Catalytic activity of NADH-ubiquinone oxidoreductase (complex I) in intact mitochondria Evidence for the slow active/inactive transition
VG Grivennikova, AN Kapustin, AD Vinogradov
Journal of Biological Chemistry 276 (12), 9038-9044, 2001
1062001
Urokinase gene transfer augments angiogenesis in ischemic skeletal and myocardial muscle
DO Traktuev, ZI Tsokolaeva, AA Shevelev, KA Talitskiy, VV Stepanova, ...
Molecular Therapy 15 (11), 1939-1946, 2007
692007
Calcium regulation of vascular smooth muscle cell–derived matrix vesicles
AN Kapustin, CM Shanahan
Trends in cardiovascular medicine 22 (5), 133-137, 2012
572012
Reactive oxygen species regulate axonal regeneration through the release of exosomal NADPH oxidase 2 complexes into injured axons
A Hervera, F De Virgiliis, I Palmisano, L Zhou, E Tantardini, G Kong, ...
Nature cell biology 20 (3), 307-319, 2018
542018
Emerging roles for vascular smooth muscle cell exosomes in calcification and coagulation
AN Kapustin, CM Shanahan
The Journal of physiology 594 (11), 2905-2914, 2016
502016
Osteocalcin: a novel vascular metabolic and osteoinductive factor?
AN Kapustin, CM Shanahan
Arteriosclerosis, thrombosis, and vascular biology 31 (10), 2169-2171, 2011
502011
Extracellular matrix proteomics identifies molecular signature of symptomatic carotid plaques
SR Langley, K Willeit, A Didangelos, LP Matic, P Skroblin, ...
The Journal of clinical investigation 127 (4), 1546-1560, 2017
472017
Targeting vascular calcification: softening-up a hard target
A Kapustin, CM Shanahan
Current opinion in pharmacology 9 (2), 84-89, 2009
362009
Prothrombin Loading of Vascular Smooth Muscle Cell–Derived Exosomes Regulates Coagulation and Calcification
AN Kapustin, M Schoppet, LJ Schurgers, JL Reynolds, R McNair, A Heiss, ...
Arteriosclerosis, thrombosis, and vascular biology 37 (3), e22-e32, 2017
342017
Fibulin-5 binds urokinase-type plasminogen activator and mediates urokinase-stimulated β1-integrin-dependent cell migration
A Kapustin, V Stepanova, N Aniol, DB Cines, A Poliakov, S Yarovoi, ...
Biochemical Journal 443 (2), 491-503, 2012
292012
Neointimal hyperplasia and calcification in medium sized arteries in adult patients with chronic kidney disease
N Chitalia, L Ross, M Krishnamoorthy, A Kapustin, CM Shanahan, ...
Seminars in dialysis 28 (3), E35-E40, 2015
152015
Calcium phosphate particles stimulate interleukin-1β release from human vascular smooth muscle cells: A role for spleen tyrosine kinase and exosome release
Y Dautova, AN Kapustin, K Pappert, M Epple, H Okkenhaug, SJ Cook, ...
Journal of molecular and cellular cardiology 115, 82-93, 2018
112018
Using macropinocytosis for intracellular delivery of therapeutic nucleic acids to tumour cells
AS Desai, MR Hunter, AN Kapustin
Philosophical Transactions of the Royal Society B 374 (1765), 20180156, 2019
42019
162 regulated exosome secretion by vascular smooth muscle cells mediates vascular calcification
A Kapustin, M Chatrou, S Kalra, I Drozdov, D Soong, M Furmanik, ...
Heart 100 (Suppl 3), A93-A94, 2014
42014
19 Elevated calcium and phosphate impair mitochondrial function in calcifying human vascular smooth muscle cell
A Kapustin, A Galkin, M Furmanik, D Alvarez-Hernandez, C Shanahan
Heart 97 (24), e8-e8, 2011
42011
Publisher Correction: Reactive oxygen species regulate axonal regeneration through the release of exosomal NADPH oxidase 2 complexes into injured axons
A Hervera, F De Virgiliis, I Palmisano, L Zhou, E Tantardini, G Kong, ...
Nature cell biology 20 (9), 1098-1098, 2018
32018
Assay for vascular calcification
CM Shanahan, AN Kapustin
US Patent 8,993,247, 2015
22015
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Artigos 1–20