Impairment of both nitric oxide‐mediated and EDHF‐type relaxation in small mesenteric arteries from rats with streptozotocin‐induced diabetes CH Leo, JL Hart, OL Woodman British journal of pharmacology 162 (2), 365-377, 2011 | 132 | 2011 |
Vascular actions of relaxin: nitric oxide and beyond CH Leo, M Jelinic, HH Ng, SA Marshall, J Novak, M Tare, KP Conrad, ... British journal of pharmacology 174 (10), 1002-1014, 2017 | 101 | 2017 |
Localization of relaxin receptors in arteries and veins, and region-specific increases in compliance and bradykinin-mediated relaxation after in vivo serelaxin treatment M Jelinic, CH Leo, EDP Uiterweer, SL Sandow, JH Gooi, ME Wlodek, ... The FASEB Journal 28 (1), 275, 2014 | 95 | 2014 |
Acute intravenous injection of serelaxin (recombinant human relaxin‐2) causes rapid and sustained bradykinin‐mediated vasorelaxation CH Leo, M Jelinic, HC Parkington, M Tare, LJ Parry Journal of the American Heart Association 3 (1), e000493, 2014 | 62 | 2014 |
Serelaxin treatment reverses vascular dysfunction and left ventricular hypertrophy in a mouse model of Type 1 diabetes HH Ng, CH Leo, D Prakoso, C Qin, RH Ritchie, LJ Parry Scientific Reports 7 (1), 39604, 2017 | 54 | 2017 |
3′, 4′-Dihydroxyflavonol reduces superoxide and improves nitric oxide function in diabetic rat mesenteric arteries CH Leo, JL Hart, OL Woodman PLoS One 6 (6), e20813, 2011 | 54 | 2011 |
Flavonols in the prevention of diabetes-induced vascular dysfunction CH Leo, OL Woodman Journal of cardiovascular pharmacology 65 (6), 532-544, 2015 | 52 | 2015 |
Serelaxin: a novel therapeutic for vascular diseases CH Leo, M Jelinic, HH Ng, M Tare, LJ Parry Trends in pharmacological sciences 37 (6), 498-507, 2016 | 48 | 2016 |
Short-term type 1 diabetes alters the mechanism of endothelium-dependent relaxation in the rat carotid artery CH Leo, A Joshi, OL Woodman American Journal of Physiology-Heart and Circulatory Physiology 299 (2 …, 2010 | 48 | 2010 |
Increased superoxide production and altered nitric oxide-mediated relaxation in the aorta of young but not old male relaxin-deficient mice HH Ng, M Jelinic, LJ Parry, CH Leo American Journal of Physiology-Heart and Circulatory Physiology 309 (2 …, 2015 | 47 | 2015 |
Endothelium-dependent nitroxyl-mediated relaxation is resistant to superoxide anion scavenging and preserved in diabetic rat aorta CH Leo, A Joshi, JL Hart, OL Woodman Pharmacological research 66 (5), 383-391, 2012 | 42 | 2012 |
Serelaxin (recombinant human relaxin-2) prevents high glucose-induced endothelial dysfunction by ameliorating prostacyclin production in the mouse aorta HH Ng, CH Leo, LJ Parry Pharmacological research 107, 220-228, 2016 | 41 | 2016 |
Time‐dependent activation of prostacyclin and nitric oxide pathways during continuous iv infusion of serelaxin (recombinant human H2 relaxin) CH Leo, M Jelinic, HH Ng, M Tare, LJ Parry British journal of pharmacology 173 (6), 1005-1017, 2016 | 41 | 2016 |
Relaxin deficiency attenuates pregnancy-induced adaptation of the mesenteric artery to angiotensin II in mice SA Marshall, CH Leo, SN Senadheera, JE Girling, M Tare, LJ Parry American Journal of Physiology-Regulatory, Integrative and Comparative …, 2016 | 40 | 2016 |
A vasoactive role for endogenous relaxin in mesenteric arteries of male mice CH Leo, M Jelinic, JH Gooi, M Tare, LJ Parry PLoS One 9 (9), e107382, 2014 | 39 | 2014 |
Relaxin as a therapeutic target for the cardiovascular complications of diabetes HH Ng, CH Leo, LJ Parry, RH Ritchie Frontiers in Pharmacology 9, 360916, 2018 | 38 | 2018 |
Post Uiterweer ED, Sandow SL, Gooi JH, Wlodek ME, Conrad KP, Parkington H, Tare M, Parry LJ. Localization of relaxin receptors in arteries and veins, and region-specific … M Jelinic, CH Leo FASEB J 28, 275-287, 2014 | 36 | 2014 |
Microglia are Selectively Activated in Endocrine and Cardiovascular Control Centres in Streptozotocin‐Induced Diabetic Rats I Rana, E Badoer, E Alahmadi, CH Leo, OL Woodman, MJ Stebbing Journal of neuroendocrinology 26 (7), 413-425, 2014 | 35 | 2014 |
Relaxin treatment reduces angiotensin II-induced vasoconstriction in pregnancy and protects against endothelial dysfunction SA Marshall, CH Leo, JE Girling, M Tare, S Beard, NJ Hannan, LJ Parry Biology of reproduction 96 (4), 895-906, 2017 | 33 | 2017 |
1, 4-Anhydro-4-seleno-d-talitol (SeTal) protects endothelial function in the mouse aorta by scavenging superoxide radicals under conditions of acute oxidative stress HH Ng, CH Leo, K O'Sullivan, SA Alexander, MJ Davies, CH Schiesser, ... Biochemical Pharmacology 128, 34-45, 2017 | 33 | 2017 |