Electrophilic probes for deciphering substrate recognition by O-GlcNAc transferase CW Hu, M Worth, D Fan, B Li, H Li, L Lu, X Zhong, Z Lin, L Wei, Y Ge, L Li, ... Nature chemical biology 13 (12), 1267-1273, 2017 | 36 | 2017 |
Distributive O-GlcNAcylation on the highly repetitive C-terminal domain of RNA polymerase II L Lu, D Fan, CW Hu, M Worth, ZX Ma, J Jiang Biochemistry 55 (7), 1149-1158, 2016 | 30 | 2016 |
Aglycone Ebselen and β-d-Xyloside Primed Glycosaminoglycans Co-contribute to Ebselen β-d-Xyloside-Induced Cytotoxicity Y Tang, S Zhang, Y Chang, D Fan, AD Agostini, L Zhang, T Jiang Journal of medicinal chemistry 61 (7), 2937-2948, 2018 | 25 | 2018 |
Targeted covalent inhibition of O-GlcNAc transferase in cells M Worth, CW Hu, H Li, D Fan, A Estevez, D Zhu, A Wang, J Jiang Chemical Communications 55 (88), 13291-13294, 2019 | 23 | 2019 |
Systematic discovery of mutation-directed neo-protein-protein interactions in cancer X Mo, Q Niu, AA Ivanov, YH Tsang, C Tang, C Shu, Q Li, K Qian, ... Cell 185 (11), 1974-1985. e12, 2022 | 18 | 2022 |
Elucidating the protein substrate recognition of O-GlcNAc transferase (OGT) toward O-GlcNAcase (OGA) using a GlcNAc electrophilic probe A Kositzke, D Fan, A Wang, H Li, M Worth, J Jiang International Journal of Biological Macromolecules 169, 51-59, 2021 | 13 | 2021 |
Exploring stereoselectivity of 3-indolyl cyclopent [b] indoles: A parallel synthesis and anti-EGFR study on human cancer cells D Fan, W Sun, P Qiu, Z Wu, Y Li, S Wan, T Jiang, L Zhang European journal of medicinal chemistry 74, 533-540, 2014 | 8 | 2014 |
Acquisition of taxane resistance by p53 inactivation in ovarian cancer cells C Shu, X Zheng, A Wuhafu, D Cicka, S Doyle, Q Niu, D Fan, K Qian, ... Acta Pharmacologica Sinica 43 (9), 2419-2428, 2022 | 7 | 2022 |
Discovery of the first chemical tools to regulate MKK3-mediated MYC activation in cancer X Yang, D Fan, AH Troha, HM Ahn, K Qian, B Liang, Y Du, H Fu, ... Bioorganic & Medicinal Chemistry 45, 116324, 2021 | 7 | 2021 |
Identification of Inhibitors of the TMPRss2 and SPIKE Interaction Through Novel uHTS Assays and Molecular Docking D Cicka, AA Ivanov, S West, D Fan, Q Niu, Y Du, H Fu Journal of Pharmacology and Experimental Therapeutics 385 (S3), 2023 | | 2023 |
Targeting MKK3-MYC complex to reduce racial survival disparity in breast cancer S West, X Yang, D Fan, YH Oum, Y Du, H Fu, AA Ivanov Cancer Research 83 (7_Supplement), 441-441, 2023 | | 2023 |
TMPRSS2 and SARS-CoV-2 SPIKE interaction assay for uHTS D Cicka, Q Niu, M Qui, K Qian, E Miller, D Fan, X Mo, AA Ivanov, ... Journal of Molecular Cell Biology 15 (3), mjad017, 2023 | | 2023 |
Ultra High-Throughput Screening Assays for Inhibitors of TMPRSS2 and SPIKE Interaction D Cicka, Q Niu, K Qian, D Fan, A Ivanov, S Sarafianos, Y Du, H Fu Journal of Biological Chemistry, S152-S152, 2023 | | 2023 |