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Dacheng Fan
Dacheng Fan
E-mail confirmado em emory.edu
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Electrophilic probes for deciphering substrate recognition by O-GlcNAc transferase
CW Hu, M Worth, D Fan, B Li, H Li, L Lu, X Zhong, Z Lin, L Wei, Y Ge, L Li, ...
Nature chemical biology 13 (12), 1267-1273, 2017
362017
Distributive O-GlcNAcylation on the highly repetitive C-terminal domain of RNA polymerase II
L Lu, D Fan, CW Hu, M Worth, ZX Ma, J Jiang
Biochemistry 55 (7), 1149-1158, 2016
302016
Aglycone Ebselen and β-d-Xyloside Primed Glycosaminoglycans Co-contribute to Ebselen β-d-Xyloside-Induced Cytotoxicity
Y Tang, S Zhang, Y Chang, D Fan, AD Agostini, L Zhang, T Jiang
Journal of medicinal chemistry 61 (7), 2937-2948, 2018
252018
Targeted covalent inhibition of O-GlcNAc transferase in cells
M Worth, CW Hu, H Li, D Fan, A Estevez, D Zhu, A Wang, J Jiang
Chemical Communications 55 (88), 13291-13294, 2019
232019
Systematic discovery of mutation-directed neo-protein-protein interactions in cancer
X Mo, Q Niu, AA Ivanov, YH Tsang, C Tang, C Shu, Q Li, K Qian, ...
Cell 185 (11), 1974-1985. e12, 2022
182022
Elucidating the protein substrate recognition of O-GlcNAc transferase (OGT) toward O-GlcNAcase (OGA) using a GlcNAc electrophilic probe
A Kositzke, D Fan, A Wang, H Li, M Worth, J Jiang
International Journal of Biological Macromolecules 169, 51-59, 2021
132021
Exploring stereoselectivity of 3-indolyl cyclopent [b] indoles: A parallel synthesis and anti-EGFR study on human cancer cells
D Fan, W Sun, P Qiu, Z Wu, Y Li, S Wan, T Jiang, L Zhang
European journal of medicinal chemistry 74, 533-540, 2014
82014
Acquisition of taxane resistance by p53 inactivation in ovarian cancer cells
C Shu, X Zheng, A Wuhafu, D Cicka, S Doyle, Q Niu, D Fan, K Qian, ...
Acta Pharmacologica Sinica 43 (9), 2419-2428, 2022
72022
Discovery of the first chemical tools to regulate MKK3-mediated MYC activation in cancer
X Yang, D Fan, AH Troha, HM Ahn, K Qian, B Liang, Y Du, H Fu, ...
Bioorganic & Medicinal Chemistry 45, 116324, 2021
72021
Identification of Inhibitors of the TMPRss2 and SPIKE Interaction Through Novel uHTS Assays and Molecular Docking
D Cicka, AA Ivanov, S West, D Fan, Q Niu, Y Du, H Fu
Journal of Pharmacology and Experimental Therapeutics 385 (S3), 2023
2023
Targeting MKK3-MYC complex to reduce racial survival disparity in breast cancer
S West, X Yang, D Fan, YH Oum, Y Du, H Fu, AA Ivanov
Cancer Research 83 (7_Supplement), 441-441, 2023
2023
TMPRSS2 and SARS-CoV-2 SPIKE interaction assay for uHTS
D Cicka, Q Niu, M Qui, K Qian, E Miller, D Fan, X Mo, AA Ivanov, ...
Journal of Molecular Cell Biology 15 (3), mjad017, 2023
2023
Ultra High-Throughput Screening Assays for Inhibitors of TMPRSS2 and SPIKE Interaction
D Cicka, Q Niu, K Qian, D Fan, A Ivanov, S Sarafianos, Y Du, H Fu
Journal of Biological Chemistry, S152-S152, 2023
2023
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