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J. Paul G. Malthouse
J. Paul G. Malthouse
Emeritus Professor of Biochemistry, University College Dublin
E-mail confirmado em ucd.ie
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Effect of acute dietary standardization on the urinary, plasma, and salivary metabolomic profiles of healthy humans
MC Walsh, L Brennan, JPG Malthouse, HM Roche, MJ Gibney
The American journal of clinical nutrition 84 (3), 531-539, 2006
3592006
A reporter group delivery system with both absolute and selective specificity for thiol groups and an improved fluorescent probe containing the 7-nitrobenzo-2-oxa-1, 3-diazole …
T Stuchbury, M Shipton, R Norris, JPG Malthouse, K Brocklehurst, ...
Biochemical Journal 151 (2), 417-432, 1975
2351975
A nuclear magnetic resonance-based demonstration of substantial oxidative l-alanine metabolism and l-alanine-enhanced glucose metabolism in a clonal pancreatic β-cell line …
L Brennan, A Shine, C Hewage, JPG Malthouse, KM Brindle, ...
Diabetes 51 (6), 1714-1721, 2002
1502002
Vinyl sulfone-based peptidomimetics as anti-trypanosomal agents: design, synthesis, biological and computational evaluation
E Dunny, W Doherty, P Evans, JPG Malthouse, D Nolan, AJS Knox
Journal of Medicinal Chemistry 56 (17), 6638-6650, 2013
1122013
Differences in the interaction of the catalytic groups of the active centres of actinidin and papain Rapid purification of fully active actinidin by covalent chromatography and …
K Brocklehurst, BS Baines, JP Malthouse
Biochemical Journal 197 (3), 739-746, 1981
1051981
13C NMR analysis reveals a link between L-glutamine metabolism, D-glucose metabolism and γ-glutamyl cycle activity in a clonal pancreatic beta-cell line
L Brennan, M Corless, C Hewage, JPG Malthouse, NH McClenaghan, ...
Diabetologia 46, 1512-1521, 2003
902003
Preparation of fully active ficin from Ficus glabrata by covalent chromatography and characterization of its active centre by using 2,2'-depyridyl disulphide as a …
JP Malthouse, K Brocklehurst
Biochemical Journal 159 (2), 221-234, 1976
761976
Detection of a tetrahedral adduct in a trypsin-chloromethyl ketone specific inhibitor complex by carbon-13 NMR
JPG Malthouse, NE Mackenzie, ASF Boyd, AI Scott
Journal of the American Chemical Society 105 (6), 1685-1686, 1983
571983
Mechanism of the reaction of papain with substrate-derived diazomethyl ketones. Implications for the difference in site specificity of halomethyl ketones for serine proteinases …
K Brocklehurst, JPG Malthouse
Biochemical Journal 175 (2), 761-764, 1978
551978
Carbon-13 NMR study of the stereospecificity of the thiohemiacetals formed on inhibition of papain by specific enantiomeric aldehydes
NE Mackenzie, SK Grant, AI Scott, JPG Malthouse
Biochemistry 25 (8), 2293-2298, 1986
531986
Structure and stereochemistry of tetrahedral inhibitor complexes of papain by direct NMR observation
MP Gamcsik, JPG Malthouse, WU Primrose, NE Mackenzie, ASF Boyd, ...
Journal of the American Chemical Society 105 (20), 6324-6325, 1983
521983
Studying Enzyme Mechanism by 13C Nuclear Magnetic Resonance
NE Mackenzie, JPG Malthouse, AI Scott
Science 225 (4665), 883-889, 1984
501984
A study of the stabilization of tetrahedral adducts by trypsin and δ-chymotrypsin
MD Finucane, JPG Malthouse
Biochemical Journal 286 (3), 889-900, 1992
461992
Carbon-13 NMR study of the ionizations within a trypsin-chloromethyl ketone inhibitor complex
JPG Malthouse, WU Primrose, NE Mackenzie, AI Scott
Biochemistry 24 (14), 3478-3487, 1985
441985
Coupling of [33S]sulphur to molybdenum(V) in different reduced forms of xanthine oxidase
JPG Malthouse, GN George, DJ Lowe, RC Bray
Biochemical Journal 199 (3), 629-637, 1981
441981
Differences in the chemical and catalytic characteristics of two crystallographically ‘identical’enzyme catalytic sites. Characterization of actinidin and papain by a …
E Salih, JPG Malthouse, D Kowlessur, M Jarvis, M O'Driscoll, ...
Biochemical Journal 247 (1), 181-193, 1987
431987
NMR and alanine scan studies of glucose-dependent insulinotropic polypeptide in water
I Alana, JC Parker, VA Gault, PR Flatt, FPM O'Harte, JPG Malthouse, ...
Journal of Biological Chemistry 281 (24), 16370-16376, 2006
412006
Reactivities of neutral and cationic forms of 2, 2′-dipyridyl disulphide towards thiolate anions. Detection of differences between the active centres of actinidin, papain and …
K Brocklehurst, T Stuchbury, JPG Malthouse
Biochemical Journal 183 (2), 233-238, 1979
381979
The case for assigning a value of approximately 4 to pKa-i of the essential histidine-cysteine interactive systems of papain, bromelain and ficin
M Shipton, MP Kierstan, JP Malthouse, T Stuchbury, K Brocklehurst
FEBS lett 50 (3), 365-368, 1975
381975
The bioactive conformation of glucose‐dependent insulinotropic polypeptide by NMR and CD spectroscopy
I Alaña, JPG Malthouse, FPM O'Harte, CM Hewage
Proteins: Structure, Function, and Bioinformatics 68 (1), 92-99, 2007
372007
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