Gurpreet Singhera
Gurpreet Singhera
Centre for Heart Lung Innovation
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ACE-2 expression in the small airway epithelia of smokers and COPD patients: implications for COVID-19
JM Leung, CX Yang, A Tam, T Shaipanich, TL Hackett, GK Singhera, ...
European Respiratory Journal 55 (5), 2020
Intrinsic phenotypic differences of asthmatic epithelium and its inflammatory responses to respiratory syncytial virus and air pollution
TL Hackett, GK Singhera, F Shaheen, P Hayden, GR Jackson, RG Hegele, ...
American journal of respiratory cell and molecular biology 45 (5), 1090-1100, 2011
Toll-like receptor 4-mediated activation of p38 mitogen-activated protein kinase is a determinant of respiratory virus entry and tropism
D Marchant, GK Singhera, S Utokaparch, TL Hackett, JH Boyd, Z Luo, X Si, ...
Journal of virology 84 (21), 11359-11373, 2010
Secretion of IL-13 by airway epithelial cells enhances epithelial repair via HB-EGF
S Allahverdian, N Harada, GK Singhera, DA Knight, DR Dorscheid
American journal of respiratory cell and molecular biology 38 (2), 153-160, 2008
Insulin-like growth factor-1 protects ischemic murine myocardium from ischemia/reperfusion associated injury
EY Davani, Z Brumme, GK Singhera, HCF Côté, PR Harrigan, ...
Critical care 7, 1-8, 2003
Erythropoietin inhibits respiratory epithelial cell apoptosis in a model of acute lung injury
R MacRedmond, GK Singhera, DR Dorscheid
European Respiratory Journal 33 (6), 1403-1414, 2009
Conjugated linoleic acid improves airway hyper‐reactivity in overweight mild asthmatics
R MacRedmond, G Singhera, S Attridge, M Bahzad, C Fava, Y Lai, ...
Clinical & Experimental Allergy 40 (7), 1071-1078, 2010
IL-13 and TH2 cytokine exposure triggers matrix metalloproteinase 7–mediated Fas ligand cleavage from bronchial epithelial cells
SJ Wadsworth, R Atsuta, JO McIntyre, TL Hackett, GK Singhera, ...
Journal of Allergy and Clinical Immunology 126 (2), 366-374. e8, 2010
Cardiac ICAM-1 mediates leukocyte-dependent decreased ventricular contractility in endotoxemic mice
EY Davani, JH Boyd, DR Dorscheid, Y Wang, A Meredith, E Chau, ...
Cardiovascular Research 72 (1), 134-142, 2006
Fast, cheap and out of control: A zero curation model for ontology development
BM Good, EM Tranfield, PC Tan, M Shehata, GK Singhera, J Gosselink, ...
Biocomputing 2006, 128-139, 2006
Urban particulate matter increases human airway epithelial cell IL-1β secretion following scratch wounding and H1N1 influenza A exposure in vitro
JA Hirota, DJ Marchant, GK Singhera, F Moheimani, DR Dorscheid, ...
Experimental lung research 41 (6), 353-362, 2015
Formation of a stable mimic of ambient particulate matter containing viable infectious respiratory syncytial virus and its dry-deposition directly onto cell cultures
TM Cruz-Sanchez, AE Haddrell, TL Hackett, GK Singhera, D Marchant, ...
Analytical chemistry 85 (2), 898-906, 2013
Hedgehog signaling in the airway epithelium of patients with chronic obstructive pulmonary disease
A Tam, M Hughes, KM McNagny, M Obeidat, TL Hackett, JM Leung, ...
Scientific reports 9 (1), 3353, 2019
Interleukin-9 and-13 inhibit spontaneous and corticosteroid induced apoptosis of normal airway epithelial cells
GK Singhera, R MacRedmond, DR Dorscheid
Experimental lung research 34 (9), 579-598, 2008
Characterization of COVID-19-associated cardiac injury: evidence for a multifactorial disease in an autopsy cohort
PJ Hanson, F Liu-Fei, C Ng, TA Minato, C Lai, AR Hossain, R Chan, ...
Laboratory Investigation 102 (8), 814-825, 2022
Increased myofibroblasts in the small airways, and relationship to remodelling and functional changes in smokers and COPD patients: potential role of epithelial–mesenchymal …
MS Eapen, W Lu, TL Hackett, GK Singhera, MQ Mahmood, A Hardikar, ...
ERJ open research 7 (2), 2021
Expression of surfactant protein D in airways of asthmatics and interleukin-13 modulation of surfactant protein D in human models of airway epithelium
J Xu, GK Singhera, DR Dorscheid
Respiratory Research 16, 1-12, 2015
Dysregulation of endocytic machinery and ACE2 in small airways of smokers and COPD patients can augment their susceptibility to SARS-CoV-2 (COVID-19) infections
MS Eapen, W Lu, TL Hackett, GK Singhera, IE Thompson, KD McAlinden, ...
American Journal of Physiology-Lung Cellular and Molecular Physiology 320 (1 …, 2021
Transcriptomic and proteomic host response to Aspergillus fumigatus conidia in an air-liquid interface model of human bronchial epithelium
A Toor, L Culibrk, GK Singhera, KM Moon, A Prudova, LJ Foster, ...
PloS one 13 (12), e0209652, 2018
Lipid nanoparticle formulations for optimal RNA-based topical delivery to murine airways
A Tam, J Kulkarni, K An, L Li, DR Dorscheid, GK Singhera, P Bernatchez, ...
European Journal of Pharmaceutical Sciences 176, 106234, 2022
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