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Simeon I. Taylor
Simeon I. Taylor
Professor of Medicine, University of Maryland School of Medicine
E-mail confirmado em medicine.umaryland.edu
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Leptin-replacement therapy for lipodystrophy
EA Oral, V Simha, E Ruiz, A Andewelt, A Premkumar, P Snell, AJ Wagner, ...
New England Journal of Medicine 346 (8), 570-578, 2002
14692002
Leptin reverses insulin resistance and hepatic steatosis in patients with severe lipodystrophy
KF Petersen, EA Oral, S Dufour, D Befroy, C Ariyan, C Yu, GW Cline, ...
The Journal of clinical investigation 109 (10), 1345-1350, 2002
9702002
Early neonatal death in mice homozygous for a null allele of the insulin receptor gene
D Accili, J Drago, EJ Lee, MD Johnson, MH Cool, P Salvatore, LD Asico, ...
Nature genetics 12 (1), 106-109, 1996
7811996
Development of a novel polygenic model of NIDDM in mice heterozygous for IR and IRS-1 null alleles
JC Brüning, J Winnay, S Bonner-Weir, SI Taylor, D Accili, CR Kahn
Cell 88 (4), 561-572, 1997
7041997
Disruption of insulin receptor substrate 2 causes type 2 diabetes because of liver insulin resistance and lack of compensatory beta-cell hyperplasia.
N Kubota, K Tobe, Y Terauchi, K Eto, T Yamauchi, R Suzuki, Y Tsubamoto, ...
Diabetes 49 (11), 1880-1889, 2000
6572000
AGPAT2 is mutated in congenital generalized lipodystrophy linked to chromosome 9q34
AK Agarwal, E Arioglu, S De Almeida, N Akkoc, SI Taylor, AM Bowcock, ...
Nature genetics 31 (1), 21-23, 2002
6032002
SGLT2 inhibitors may predispose to ketoacidosis
SI Taylor, JE Blau, KI Rother
The Journal of Clinical Endocrinology & Metabolism 100 (8), 2849-2852, 2015
5922015
Physiological role of Akt in insulin-stimulated translocation of GLUT4 in transfected rat adipose cells
LN Cong, H Chen, Y Li, L Zhou, MA McGibbon, SI Taylor, MJ Quon
Molecular endocrinology 11 (13), 1881-1890, 1997
4901997
Insulin resistance or insulin deficiency: which is the primary cause of NIDDM?
SI Taylor, D Accili, Y Imai
Diabetes 43 (6), 735-741, 1994
4751994
Lilly Lecture: molecular mechanisms of insulin resistance: lessons from patients with mutations in the insulin-receptor gene
SI Taylor
Diabetes 41 (11), 1473-1490, 1992
4661992
Diabetes mellitus: a fundamental and clinical text
D LeRoith, SI Taylor, JM Olefsky
Lippincott Williams & Wilkins, 2004
4462004
Point mutation causing a single amino acid substitution in the hormone binding domain of the glucocorticoid receptor in familial glucocorticoid resistance.
DM Hurley, D Accili, CA Stratakis, M Karl, N Vamvakopoulos, E Rorer, ...
The Journal of clinical investigation 87 (2), 680-686, 1991
4341991
Deconstructing type 2 diabetes
SI Taylor
Cell 97 (1), 9-12, 1999
4281999
Insulin stimulates both leptin secretion and production by rat white adipose tissue
VA Barr, D Malide, MJ Zarnowski, SI Taylor, SW Cushman
Endocrinology 138 (10), 4463-4472, 1997
4211997
Mutations in the insulin receptor gene
SI Taylor, A Cama, D Accili, F Barbetti, MJ Quon, MDLL Sierra, Y Suzuki, ...
Endocrine Reviews 13 (3), 566-595, 1992
4031992
Two mutant alleles of the insulin receptor gene in a patient with extreme insulin resistance
T Kadowaki, CL Bevins, A Cama, K Ojamaa, B Marcus-Samuels, ...
Science 240 (4853), 787-790, 1988
3841988
Efficacy and safety of troglitazone in the treatment of lipodystrophy syndromes
E Arioglu, J Duncan-Morin, N Sebring, KI Rother, N Gottlieb, J Lieberman, ...
Annals of internal medicine 133 (4), 263-274, 2000
3822000
Human orthologs of yeast vacuolar protein sorting proteins Vps26, 29, and 35: assembly into multimeric complexes
CR Haft, ML Sierra, R Bafford, MA Lesniak, VA Barr, SI Taylor
Molecular biology of the cell 11 (12), 4105-4116, 2000
3572000
Mutational and haplotype analyses of families with familial partial lipodystrophy (Dunnigan variety) reveal recurrent missense mutations in the globular C-terminal domain of …
RA Speckman, A Garg, F Du, L Bennett, R Veile, E Arioglu, SI Taylor, ...
The American Journal of Human Genetics 66 (4), 1192-1198, 2000
3552000
Clinical course of genetic diseases of the insulin receptor (type A and Rabson-Mendenhall syndromes): a 30-year prospective
C Musso, E Cochran, SA Moran, MC Skarulis, EA Oral, S Taylor, ...
Medicine 83 (4), 209-222, 2004
3312004
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