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Kevin J Robbins
Kevin J Robbins
E-mail confirmado em astrazeneca.com
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Peptide Macrocyclization Inspired by Non-Ribosomal Imine Natural Products
LR Malins, JN deGruyter, KJ Robbins, PM Scola, MD Eastgate, ...
Journal of the American Chemical Society 139 (14), 5233-5241, 2017
1152017
Mechanistic studies of peptide self-assembly: Transient α-helices to stable β-sheets
G Liu, A Prabhakar, D Aucoin, M Simon, S Sparks, KJ Robbins, A Sheen, ...
Journal of the American Chemical Society 132 (51), 18223-18232, 2010
942010
Curcumin modulates the self-assembly of the islet amyloid polypeptide by disassembling α-helix
S Sparks, G Liu, KJ Robbins, ND Lazo
Biochemical and Biophysical Research Communications 422 (4), 551-555, 2012
782012
Conformational Analysis of Thioflavin T Bound to the Surface of Amyloid Fibrils
KJ Robbins, G Liu, V Selmani, ND Lazo
Langmuir 28 (48), 16490-16495, 2012
622012
Development of New Benzenesulfonamides As Potent and Selective Nav1.7 Inhibitors for the Treatment of Pain
YJ Wu, J Guernon, J Shi, J Ditta, KJ Robbins, R Rajamani, A Easton, ...
Journal of Medicinal Chemistry 60 (6), 2513-2525, 2017
362017
Detection of strongly bound thioflavin T species in amyloid fibrils by ligand-detected 1H NMR
KJ Robbins, G Liu, G Lin, ND Lazo
The Journal of Physical Chemistry Letters 2 (7), 735-740, 2011
332011
NMR in drug design
MJ Harner, L Mueller, KJ Robbins, MD Reily
Archives of biochemistry and biophysics 628, 132-147, 2017
322017
Kinetic Profile of Amyloid Formation in the Presence of an Aromatic Inhibitor by Nuclear Magnetic Resonance
G Liu, JC Gaines, KJ Robbins, ND Lazo
ACS Medicinal Chemistry Letters 3 (10), 856-859, 2012
212012
Discovery of morpholine-based aryl sulfonamides as Na v 1.7 inhibitors
YJ Wu, J Guernon, A McClure, B Venables, R Rajamani, KJ Robbins, ...
Bioorganic & Medicinal Chemistry Letters, 2018
112018
K114 (trans, trans)‐bromo‐2, 5‐bis (4‐hydroxystyryl) benzene is an efficient detector of cationic amyloid fibrils
V Selmani, KJ Robbins, VA Ivancic, ND Lazo
Protein Science, 2014
82014
Contextual role of a salt bridge in the phage P22 coat protein I-domain
C Harprecht, O Okifo, KJ Robbins, T Motwani, AT Alexandrescu, ...
Journal of Biological Chemistry 291 (21), 11359-11372, 2016
72016
Helix-dipole effects in peptide self-assembly to amyloid
G Liu, KJ Robbins, S Sparks, V Selmani, KM Bilides, EE Gomes, ND Lazo
Biochemistry 51 (20), 4167-4174, 2012
62012
Discovery, Optimization, and Biological Evaluation of Arylpyridones as Cbl-b Inhibitors
AM Mfuh, JA Boerth, G Bommakanti, C Chan, AJ Chinn, E Code, PJ Fricke, ...
Journal of Medicinal Chemistry 67 (2), 1500-1512, 2024
12024
Discovery of a Novel Benzodiazepine Series of Cbl-b Inhibitors for the Enhancement of Antitumor Immunity
JA Boerth, AJ Chinn, M Schimpl, G Bommakanti, C Chan, EL Code, ...
ACS Medicinal Chemistry Letters 14 (12), 1848-1856, 2023
12023
Discovery of a macrocyclic peptide inhibitor of programmed death-ligand 1 (PD-L1)
P Scola, E Gillis, K Boy, D Langley, D Donnelly, M Miller, L Lombardo, ...
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 254, 2017
2017
Solution-state NMR studies of thioflavin T bound to the surface of amyloid fibrils
KJ Robbins, G Liu, V Selmani, ND Lazo
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 245, 2013
2013
Ligand-detected 1H NMR Studies of Thioflavin T--Amyloid Fibril Complexes
KJ Robbins
CLARK UNIVERSITY, 2013
2013
Using ligand-detected NMR to probe the aggregation of amylin
KJ Robbins, LG Lin, LND Lazo
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 240, 2010
2010
CHED 1197-New soft scorpionate complexes of vanadium
KJ Robbins, CD Abernethy
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 235, 2008
2008
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Artigos 1–19