| Single-cell RNA-seq of a soft-tissue sarcoma model reveals the critical role of tumor-expressed MIF in shaping macrophage heterogeneity FHG Tessaro, EY Ko, M De Simone, R Piras, MT Broz, HS Goodridge, ... Cell reports 39 (12), 2022 | 18 | 2022 |
| circCsnk1g3-and circAnkib1-regulated interferon responses in sarcoma promote tumorigenesis by shaping the immune microenvironment R Piras, EY Ko, C Barrett, M De Simone, X Lin, MT Broz, FHG Tessaro, ... Nature Communications 13 (1), 7243, 2022 | 8 | 2022 |
| Metabolic targeting of cancer associated fibroblasts overcomes T-cell exclusion and chemoresistance in soft-tissue sarcomas MT Broz, EY Ko, K Ishaya, J Xiao, M De Simone, XP Hoi, R Piras, B Gala, ... Nature Communications 15 (1), 2498, 2024 | | 2024 |
| 1432 Cancer-associated fibroblasts metabolic targeting overcomes T-cell exclusion and chemoresistance M Broz, E Ko, K Ishaya, J Xiao, M DeSimone, XP Hoi, R Piras, B Gala, ... Journal for ImmunoTherapy of Cancer 11 (Suppl 1), 2023 | | 2023 |
| Glucose dependent CD73+ CAFs enforce a tumor metabolic barrier that promotes T cell exclusion M Broz, E Ko, J Xiao, M DeSimone, R Piras, K Ishaya, XP Hoi, J Guarnerio Cancer Research 83 (7_Supplement), 1255-1255, 2023 | | 2023 |
| Profiling tumor microenvironment for therapeutic intervention to soft-tissue sarcomas JF Xiao, M Broz, R Piras, K Ishaya, E Ko, J Guarnerio Cancer Research 83 (7_Supplement), 1364-1364, 2023 | | 2023 |
| Uncovering transcriptional signatures of drug resistant tumor cells: Mechanisms of therapeutic resistance and opportunities for combination therapies MT Broz, M DeSimone, E Ko, R Piras, J Guarnerio CANCER IMMUNOLOGY RESEARCH 10 (12), 2022 | | 2022 |
| Abstract A29: Uncovering transcriptional signatures of drug resistant tumor cells: Mechanisms of therapeutic resistance and opportunities for combination therapies MT Broz, M DeSimone, E Ko, R Piras, J Guarnerio Cancer Immunology Research 10 (12_Supplement), A29-A29, 2022 | | 2022 |
