| RIP3 mediates the embryonic lethality of caspase-8-deficient mice WJ Kaiser, JW Upton, AB Long, D Livingston-Rosanoff, LP Daley-Bauer, ... Nature 471 (7338), 368-372, 2011 | 1068 | 2011 |
| Toll-like receptor 3-mediated necrosis via TRIF, RIP3, and MLKL WJ Kaiser, H Sridharan, C Huang, P Mandal, JW Upton, PJ Gough, ... Journal of Biological Chemistry 288 (43), 31268-31279, 2013 | 917 | 2013 |
| DAI/ZBP1/DLM-1 complexes with RIP3 to mediate virus-induced programmed necrosis that is targeted by murine cytomegalovirus vIRA JW Upton, WJ Kaiser, ES Mocarski Cell host & microbe 11 (3), 290-297, 2012 | 763 | 2012 |
| Virus inhibition of RIP3-dependent necrosis JW Upton, WJ Kaiser, ES Mocarski Cell host & microbe 7 (4), 302-313, 2010 | 639 | 2010 |
| RIP3 induces apoptosis independent of pronecrotic kinase activity P Mandal, SB Berger, S Pillay, K Moriwaki, C Huang, H Guo, JD Lich, ... Molecular cell 56 (4), 481-495, 2014 | 566 | 2014 |
| Viral infection and the evolution of caspase 8-regulated apoptotic and necrotic death pathways ES Mocarski, JW Upton, WJ Kaiser Nature Reviews Immunology 12 (2), 79-88, 2012 | 353 | 2012 |
| DAI senses influenza A virus genomic RNA and activates RIPK3-dependent cell death RJ Thapa, JP Ingram, KB Ragan, S Nogusa, DF Boyd, AA Benitez, ... Cell host & microbe 20 (5), 674-681, 2016 | 343 | 2016 |
| Receptor-interacting protein homotypic interaction motif-dependent control of NF-κB activation via the DNA-dependent activator of IFN regulatory factors WJ Kaiser, JW Upton, ES Mocarski The Journal of Immunology 181 (9), 6427-6434, 2008 | 317 | 2008 |
| Influenza virus Z-RNAs induce ZBP1-mediated necroptosis T Zhang, C Yin, DF Boyd, G Quarato, JP Ingram, M Shubina, KB Ragan, ... Cell 180 (6), 1115-1129. e13, 2020 | 310 | 2020 |
| Cytomegalovirus M45 cell death suppression requires receptor-interacting protein (RIP) homotypic interaction motif (RHIM)-dependent interaction with RIP1 JW Upton, WJ Kaiser, ES Mocarski Journal of biological chemistry 283 (25), 16966-16970, 2008 | 227 | 2008 |
| Sensing of viral and endogenous RNA by ZBP 1/DAI induces necroptosis J Maelfait, L Liverpool, A Bridgeman, KB Ragan, JW Upton, J Rehwinkel The EMBO journal 36 (17), 2529-2543, 2017 | 201 | 2017 |
| Staying alive: cell death in antiviral immunity JW Upton, FKM Chan Molecular cell 54 (2), 273-280, 2014 | 168 | 2014 |
| Viral modulation of programmed necrosis WJ Kaiser, JW Upton, ES Mocarski Current opinion in virology 3 (3), 296-306, 2013 | 168 | 2013 |
| Electrochemical detection of a single cytomegalovirus at an ultramicroelectrode and its antibody anchoring JE Dick, AT Hilterbrand, A Boika, JW Upton, AJ Bard Proceedings of the National Academy of Sciences 112 (17), 5303-5308, 2015 | 159 | 2015 |
| Inhibition of DAI-dependent necroptosis by the Z-DNA binding domain of the vaccinia virus innate immune evasion protein, E3 H Koehler, S Cotsmire, J Langland, KV Kibler, D Kalman, JW Upton, ... Proceedings of the National Academy of Sciences 114 (43), 11506-11511, 2017 | 135 | 2017 |
| Programmed necrosis in microbial pathogenesis H Sridharan, JW Upton Trends in microbiology 22 (4), 199-207, 2014 | 115 | 2014 |
| Evasion of innate cytosolic DNA sensing by a gammaherpesvirus facilitates establishment of latent infection C Sun, SA Schattgen, P Pisitkun, JP Jorgensen, AT Hilterbrand, LJ Wang, ... The Journal of Immunology 194 (4), 1819-1831, 2015 | 109 | 2015 |
| Enzymatically enhanced collisions on ultramicroelectrodes for specific and rapid detection of individual viruses JE Dick, AT Hilterbrand, LM Strawsine, JW Upton, AJ Bard Proceedings of the National Academy of Sciences 113 (23), 6403-6408, 2016 | 105 | 2016 |
| Species-independent contribution of ZBP1/DAI/DLM-1-triggered necroptosis in host defense against HSV1 H Guo, RP Gilley, A Fisher, R Lane, VJ Landsteiner, KB Ragan, ... Cell death & disease 9 (8), 816, 2018 | 104 | 2018 |
| Murine cytomegalovirus IE 3‐dependent transcription is required for DAI/ZBP 1‐mediated necroptosis H Sridharan, KB Ragan, H Guo, RP Gilley, VJ Landsteiner, WJ Kaiser, ... EMBO reports 18 (8), 1429-1441, 2017 | 81 | 2017 |
Edward MocarskiEmeritus Professor, Stanford University (2006) and Emory University (2021)Verified email at stanford.edu
