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Hilary A. Kenny
Hilary A. Kenny
Gordon Center of Integrative Sciences, University of Chicago
E-mail confirmado em uchicago.edu
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Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth
KM Nieman, HA Kenny, CV Penicka, A Ladanyi, R Buell-Gutbrod, ...
Nature medicine 17 (11), 1498-1503, 2011
21972011
The initial steps of ovarian cancer cell metastasis are mediated by MMP-2 cleavage of vitronectin and fibronectin
HA Kenny, S Kaur, LM Coussens, E Lengyel
The Journal of clinical investigation 118 (4), 1367-1379, 2008
4332008
Loss of E-cadherin promotes ovarian cancer metastasis via α5-integrin, which is a therapeutic target
K Sawada, AK Mitra, AR Radjabi, V Bhaskar, EO Kistner, M Tretiakova, ...
Cancer research 68 (7), 2329-2339, 2008
4262008
Adipocyte-induced CD36 expression drives ovarian cancer progression and metastasis
A Ladanyi, A Mukherjee, HA Kenny, A Johnson, AK Mitra, S Sundaresan, ...
Oncogene 37 (17), 2285-2301, 2018
4132018
Neutrophils facilitate ovarian cancer premetastatic niche formation in the omentum
WJ Lee, SY Ko, MS Mohamed, HA Kenny, E Lengyel, H Naora
Journal of Experimental Medicine 216 (1), 176-194, 2019
3282019
c-Met overexpression is a prognostic factor in ovarian cancer and an effective target for inhibition of peritoneal dissemination and invasion
K Sawada, AR Radjabi, N Shinomiya, E Kistner, H Kenny, AR Becker, ...
Cancer research 67 (4), 1670-1679, 2007
3252007
Mesothelial cells promote early ovarian cancer metastasis through fibronectin secretion
HA Kenny, CY Chiang, EA White, EM Schryver, M Habis, IL Romero, ...
The Journal of clinical investigation 124 (10), 4614-4628, 2014
3112014
Use of a novel 3D culture model to elucidate the role of mesothelial cells, fibroblasts and extra‐cellular matrices on adhesion and invasion of ovarian cancer cells to the omentum
HA Kenny, T Krausz, SD Yamada, E Lengyel
International journal of cancer 121 (7), 1463-1472, 2007
2972007
Fibroblasts mobilize tumor cell glycogen to promote proliferation and metastasis
M Curtis, HA Kenny, B Ashcroft, A Mukherjee, A Johnson, Y Zhang, ...
Cell metabolism 29 (1), 141-155. e9, 2019
2362019
Epithelial ovarian cancer experimental models
E Lengyel, JE Burdette, HA Kenny, D Matei, J Pilrose, P Haluska, ...
Oncogene 33 (28), 3619-3633, 2014
2352014
MMP-2 functions as an early response protein in ovarian cancer metastasis
HA Kenny, E Lengyel
Cell cycle 8 (5), 683-688, 2009
1922009
Quantitative high throughput screening using a primary human three-dimensional organotypic culture predicts in vivo efficacy
HA Kenny, M Lal-Nag, EA White, M Shen, CY Chiang, AK Mitra, Y Zhang, ...
Nature communications 6 (1), 6220, 2015
1852015
Ovarian follicle development requires Smad3
D Tomic, KP Miller, HA Kenny, TK Woodruff, P Hoyer, JA Flaws
Molecular endocrinology 18 (9), 2224-2240, 2004
1682004
Neutrophil elastase selectively kills cancer cells and attenuates tumorigenesis
C Cui, K Chakraborty, XA Tang, G Zhou, KQ Schoenfelt, KM Becker, ...
Cell 184 (12), 3163-3177. e21, 2021
1582021
Thrombin induces tumor invasion through the induction and association of matrix metalloproteinase-9 and β1-integrin on the cell surface
AR Radjabi, K Sawada, S Jagadeeswaran, A Eichbichler, HA Kenny, ...
Journal of Biological Chemistry 283 (5), 2822-2834, 2008
1072008
Cancer-derived small extracellular vesicles promote angiogenesis by heparin-bound, bevacizumab-insensitive VEGF, independent of vesicle uptake
SY Ko, WJ Lee, HA Kenny, LH Dang, LM Ellis, E Jonasch, E Lengyel, ...
Communications Biology 2 (1), 386, 2019
1002019
Molecular pathways: trafficking of metabolic resources in the tumor microenvironment
IL Romero, A Mukherjee, HA Kenny, LM Litchfield, E Lengyel
Clinical Cancer Research 21 (4), 680-686, 2015
952015
Targeting the urokinase plasminogen activator receptor inhibits ovarian cancer metastasis
HA Kenny, P Leonhardt, A Ladanyi, SD Yamada, A Montag, HK Im, ...
Clinical Cancer Research 17 (3), 459-471, 2011
922011
β3-integrin expression on tumor cells inhibits tumor progression, reduces metastasis, and is associated with a favorable prognosis in patients with ovarian cancer
S Kaur, HA Kenny, S Jagadeeswaran, MR Zillhardt, AG Montag, E Kistner, ...
The American journal of pathology 175 (5), 2184-2196, 2009
902009
The first line of intra-abdominal metastatic attack: breaching the mesothelial cell layer
HA Kenny, KM Nieman, AK Mitra, E Lengyel
Cancer discovery 1 (2), 100-102, 2011
862011
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Artigos 1–20