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Derek Sim
Derek Sim
Associate Research Professsor Penn State University
E-mail confirmado em psu.edu
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Disentangling genetic variation for resistance and tolerance to infectious diseases in animals
L Råberg, D Sim, AF Read
Science 318 (5851), 812-814, 2007
8092007
Fungal pathogen reduces potential for malaria transmission
S Blanford, BHK Chan, N Jenkins, D Sim, RJ Turner, AF Read, ...
Science 308 (5728), 1638-1641, 2005
4352005
Within‐host competition in genetically diverse malaria infections: parasite virulence and competitive success
AS Bell, JC De. Roode, D Sim, AF Read
Evolution 60 (7), 1358-1371, 2006
2792006
Malaria-induced changes in host odors enhance mosquito attraction
CM De Moraes, NM Stanczyk, HS Betz, H Pulido, DG Sim, AF Read, ...
Proceedings of the National Academy of Sciences 111 (30), 11079-11084, 2014
1732014
Aggressive chemotherapy and the selection of drug resistant pathogens
S Huijben, AS Bell, DG Sim, D Tomasello, N Mideo, T Day, AF Read
PLoS pathogens 9 (9), e1003578, 2013
1042013
Next step in the ongoing arms race between myxoma virus and wild rabbits in Australia is a novel disease phenotype
PJ Kerr, IM Cattadori, J Liu, DG Sim, JW Dodds, JW Brooks, MJ Kennett, ...
Proceedings of the National Academy of Sciences 114 (35), 9397-9402, 2017
842017
Chemotherapy, within-host ecology and the fitness of drug-resistant malaria parasites
S Huijben, WA Nelson, AR Wargo, DG Sim, DR Drew, AF Read
Evolution 64 (10), 2952-2968, 2010
822010
Resource limitation prevents the emergence of drug resistance by intensifying within-host competition
N Wale, DG Sim, MJ Jones, R Salathe, T Day, AF Read
Proceedings of the National Academy of Sciences 114 (52), 13774-13779, 2017
712017
The Evolutionary Consequences of Blood-Stage Vaccination on the Rodent Malaria Plasmodium chabaudi
VC Barclay, D Sim, BHK Chan, LA Nell, MA Rabaa, AS Bell, RF Anders, ...
Public Library of Science 10 (7), e1001368, 2012
712012
The fitness of drug‐resistant malaria parasites in a rodent model: multiplicity of infection
S Huijben, DG Sim, WA Nelson, AF Read
Journal of evolutionary biology 24 (11), 2410-2422, 2011
492011
Rapid Response to Selection, Competitive Release and Increased Transmission Potential of Artesunate-Selected Plasmodium chabaudi Malaria Parasites
LC Pollitt, S Huijben, DG Sim, RM Salathé, MJ Jones, AF Read
PLoS pathogens 10 (4), e1004019, 2014
372014
Enhanced transmission of drug-resistant parasites to mosquitoes following drug treatment in rodent malaria
AS Bell, S Huijben, KP Paaijmans, DG Sim, BHK Chan, WA Nelson, ...
PloS one 7 (6), e37172, 2012
372012
Virulence, drug sensitivity and transmission success in the rodent malaria, Plasmodium chabaudi
P Schneider, AS Bell, DG Sim, AJ O'Donnell, S Blanford, KP Paaijmans, ...
Proceedings of the Royal Society B: Biological Sciences 279 (1747), 4677-4685, 2012
362012
A nutrient mediates intraspecific competition between rodent malaria parasites in vivo
N Wale, DG Sim, AF Read
Proceedings of the Royal Society B: Biological Sciences 284 (1859), 20171067, 2017
352017
Transmission and protection against reinfection in the ferret model with the SARS-CoV-2 USA-WA1/2020 reference isolate
DR Patel, CJ Field, KM Septer, DG Sim, MJ Jones, TA Heinly, ...
Journal of virology 95 (13), 10.1128/jvi. 02232-20, 2021
262021
Genomic and phenotypic characterization of myxoma virus from Great Britain reveals multiple evolutionary pathways distinct from those in Australia
PJ Kerr, IM Cattadori, MB Rogers, A Fitch, A Geber, J Liu, DG Sim, B Boag, ...
PLoS pathogens 13 (3), e1006252, 2017
252017
A murine model to study epilepsy and SUDEP induced by malaria infection
P Ssentongo, AE Robuccio, G Thuku, DG Sim, A Nabi, F Bahari, ...
Scientific reports 7 (1), 43652, 2017
182017
An adjunctive therapy administered with an antibiotic prevents enrichment of antibiotic-resistant clones of a colonizing opportunistic pathogen
VJ Morley, CL Kinnear, DG Sim, SN Olson, LM Jackson, E Hansen, ...
Elife 9, e58147, 2020
172020
The Effect of Immunodeficiency on the Evolution of Virulence: An Experimental Test with the Rodent Malaria Plasmodium chabaudi
VC Barclay, DA Kennedy, VC Weaver, D Sim, JO Lloyd-Smith, AF Read
The American Naturalist 184 (S1), S47-S57, 2014
172014
The contribution of host cell-directed vs. parasite-directed immunity to the disease and dynamics of malaria infections
N Wale, MJ Jones, DG Sim, AF Read, AA King
Proceedings of the National Academy of Sciences 116 (44), 22386-22392, 2019
162019
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