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Veit Hornung
Veit Hornung
Gene Center and Department of Biochemistry, Ludwig-Maximilians-University Munich
Verified email at genzentrum.lmu.de - Homepage
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Year
A mammalian microRNA expression atlas based on small RNA library sequencing
P Landgraf, M Rusu, R Sheridan, A Sewer, N Iovino, A Aravin, S Pfeffer, ...
Cell 129 (7), 1401-1414, 2007
44502007
NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals
P Duewell, H Kono, KJ Rayner, CM Sirois, G Vladimer, FG Bauernfeind, ...
Nature 464 (7293), 1357-1361, 2010
39372010
Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization
V Hornung, F Bauernfeind, A Halle, EO Samstad, H Kono, KL Rock, ...
Nature immunology 9 (8), 847-856, 2008
33152008
5'-Triphosphate RNA is the ligand for RIG-I
V Hornung, J Ellegast, S Kim, K Brzózka, A Jung, H Kato, H Poeck, ...
science 314 (5801), 994-997, 2006
30672006
Cutting edge: NF-κB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression
FG Bauernfeind, G Horvath, A Stutz, ES Alnemri, K MacDonald, D Speert, ...
The Journal of Immunology 183 (2), 787-791, 2009
28822009
AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC
V Hornung, A Ablasser, M Charrel-Dennis, F Bauernfeind, G Horvath, ...
Nature 458 (7237), 514-518, 2009
27572009
The NALP3 inflammasome is involved in the innate immune response to amyloid-β
A Halle, V Hornung, GC Petzold, CR Stewart, BG Monks, T Reinheckel, ...
Nature immunology 9 (8), 857-865, 2008
26652008
Quantitative expression of toll-like receptor 1–10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides
V Hornung, S Rothenfusser, S Britsch, A Krug, B Jahrsdörfer, T Giese, ...
The Journal of immunology 168 (9), 4531-4537, 2002
26072002
Sequence-specific potent induction of IFN-α by short interfering RNA in plasmacytoid dendritic cells through TLR7
V Hornung, M Guenthner-Biller, C Bourquin, A Ablasser, M Schlee, ...
Nature medicine 11 (3), 263-270, 2005
17252005
The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses
VAK Rathinam, Z Jiang, SN Waggoner, S Sharma, LE Cole, L Waggoner, ...
Nature immunology 11 (5), 395-402, 2010
14672010
cGAS produces a 2′-5′-linked cyclic dinucleotide second messenger that activates STING
A Ablasser, M Goldeck, T Cavlar, T Deimling, G Witte, I Röhl, KP Hopfner, ...
Nature 498 (7454), 380-384, 2013
14412013
Identification of CpG oligonucleotide sequences with high induction of IFN‐α/β in plasmacytoid dendritic cells
A Krug, S Rothenfusser, V Hornung, B Jahrsdörfer, S Blackwell, ZK Ballas, ...
European journal of immunology 31 (7), 2154-2163, 2001
11842001
RIG-I-dependent sensing of poly (dA: dT) through the induction of an RNA polymerase III–transcribed RNA intermediate
A Ablasser, F Bauernfeind, G Hartmann, E Latz, KA Fitzgerald, V Hornung
Nature immunology 10 (10), 1065-1072, 2009
10802009
Toll‐like receptor expression reveals CpG DNA as a unique microbial stimulus for plasmacytoid dendritic cells which synergizes with CD40 ligand to induce high amounts of IL‐12
A Krug, A Towarowski, S Britsch, S Rothenfusser, V Hornung, R Bals, ...
European journal of immunology 31 (10), 3026-3037, 2001
10612001
Recognition of 5′ triphosphate by RIG-I helicase requires short blunt double-stranded RNA as contained in panhandle of negative-strand virus
M Schlee, A Roth, V Hornung, CA Hagmann, V Wimmenauer, W Barchet, ...
Immunity 31 (1), 25-34, 2009
9382009
Molecular mechanisms and cellular functions of cGAS–STING signalling
KP Hopfner, V Hornung
Nature reviews Molecular cell biology 21 (9), 501-521, 2020
9372020
Structural mechanism of cytosolic DNA sensing by cGAS
F Civril, T Deimling, CC de Oliveira Mann, A Ablasser, M Moldt, G Witte, ...
Nature 498 (7454), 332-337, 2013
7372013
Human monocytes engage an alternative inflammasome pathway
MM Gaidt, TS Ebert, D Chauhan, T Schmidt, JL Schmid-Burgk, F Rapino, ...
Immunity 44 (4), 833-846, 2016
7302016
Cutting edge: reactive oxygen species inhibitors block priming, but not activation, of the NLRP3 inflammasome
F Bauernfeind, E Bartok, A Rieger, L Franchi, G Núñez, V Hornung
The Journal of Immunology 187 (2), 613-617, 2011
6642011
Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1β production
H Poeck, M Bscheider, O Gross, K Finger, S Roth, M Rebsamen, ...
Nature immunology 11 (1), 63-69, 2010
6522010
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