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Matthias Geyer
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Year
Microglia-derived ASC specks cross-seed amyloid-β in Alzheimer’s disease
C Venegas, S Kumar, BS Franklin, T Dierkes, R Brinkschulte, D Tejera, ...
Nature 552 (7685), 355-361, 2017
7982017
Structure–function relationships in HIV‐1 Nef
M Geyer, OT Fackler, BM Peterlin
EMBO reports, 2001
5002001
The RNA polymerase II carboxy-terminal domain (CTD) code
D Eick, M Geyer
Chemical reviews 113 (11), 8456-8490, 2013
4562013
Substrate-assisted catalysis as a mechanism for GTP hydrolysis of p21ras and other GTP-binding proteins
T Schweins, M Geyer, K Scheffzek, A Warshel, HR Kalbitzer, ...
Nature structural biology 2 (1), 36-44, 1995
3341995
Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape
PA Koenig, H Das, H Liu, BM Kümmerer, FN Gohr, LM Jenster, ...
Science 371 (6530), eabe6230, 2021
3272021
Activation of Vav by Nef induces cytoskeletal rearrangements and downstream effector functions
OT Fackler, W Luo, M Geyer, AS Alberts, BM Peterlin
Molecular cell 3 (6), 729-739, 1999
3171999
Formins as effector proteins of Rho GTPases
S Kühn, M Geyer
Small GTPases 5 (3), e983876, 2014
3162014
The control of HIV transcription: keeping RNA polymerase II on track
M Ott, M Geyer, Q Zhou
Cell host & microbe 10 (5), 426-435, 2011
3132011
NLRP3 inflammasome assembly is regulated by phosphorylation of the pyrin domain
A Stutz, CC Kolbe, R Stahl, GL Horvath, BS Franklin, O van Ray, ...
Journal of Experimental Medicine 214 (6), 1725-1736, 2017
3072017
Covalent targeting of remote cysteine residues to develop CDK12 and CDK13 inhibitors
T Zhang, N Kwiatkowski, CM Olson, SE Dixon-Clarke, BJ Abraham, ...
Nature chemical biology 12 (10), 876-884, 2016
3032016
Fifteen formins for an actin filament: a molecular view on the regulation of human formins
A Schönichen, M Geyer
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1803 (2), 152-163, 2010
2892010
GEFs, GAPs, GDIs and effectors: taking a closer (3D) look at the regulation of Ras-related GTP-binding proteins
M Geyer, A Wittinghofer
Current opinion in structural biology 7 (6), 786-792, 1997
2771997
Conformational Transitions in p21ras and in Its Complexes with the Effector Protein Raf-RBD and the GTPase Activating Protein GAP
M Geyer, T Schweins, C Herrmann, T Prisner, A Wittinghofer, HR Kalbitzer
Biochemistry 35 (32), 10308-10320, 1996
2771996
CDK12 inhibition reverses de novo and acquired PARP inhibitor resistance in BRCA wild-type and mutated models of triple-negative breast cancer
SF Johnson, C Cruz, AK Greifenberg, S Dust, DG Stover, D Chi, ...
Cell reports 17 (9), 2367-2381, 2016
2622016
Brd4 activates P-TEFb for RNA polymerase II CTD phosphorylation
F Itzen, AK Greifenberg, CA Bösken, M Geyer
Nucleic acids research 42 (12), 7577-7590, 2014
2492014
FMNL2 drives actin-based protrusion and migration downstream of Cdc42
J Block, D Breitsprecher, S Kühn, M Winterhoff, F Kage, R Geffers, ...
Current Biology 22 (11), 1005-1012, 2012
2282012
Rational discovery of molecular glue degraders via scalable chemical profiling
C Mayor-Ruiz, S Bauer, M Brand, Z Kozicka, M Siklos, H Imrichova, ...
Nature chemical biology 16 (11), 1199-1207, 2020
2172020
Tat competes with HEXIM1 to increase the active pool of P-TEFb for HIV-1 transcription
M Barboric, JHN Yik, N Czudnochowski, Z Yang, R Chen, X Contreras, ...
Nucleic acids research 35 (6), 2003-2012, 2007
2062007
Serine-7 but not serine-5 phosphorylation primes RNA polymerase II CTD for P-TEFb recognition
N Czudnochowski, CA Bösken, M Geyer
Nature communications 3 (1), 842, 2012
2022012
CDK12 loss in cancer cells affects DNA damage response genes through premature cleavage and polyadenylation
M Krajewska, R Dries, AV Grassetti, S Dust, Y Gao, H Huang, B Sharma, ...
Nature communications 10 (1), 1757, 2019
1932019
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