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Michael Wördehoff
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Structural insights from lipid-bilayer nanodiscs link α-Synuclein membrane-binding modes to amyloid fibril formation
T Viennet, MM Wördehoff, B Uluca, C Poojari, H Shaykhalishahi, ...
Communications biology 1 (1), 44, 2018
1002018
Single fibril growth kinetics of α-synuclein
MM Wördehoff, O Bannach, H Shaykhalishahi, A Kulawik, S Schiefer, ...
Journal of molecular biology 427 (6), 1428-1435, 2015
632015
α-Synuclein aggregation monitored by thioflavin T fluorescence assay
MM Wördehoff, W Hoyer
Bio-protocol 8 (14), e2941-e2941, 2018
572018
Opposed effects of dityrosine formation in soluble and aggregated α-synuclein on fibril growth
MM Wördehoff, H Shaykhalishahi, L Groß, L Gremer, M Stoldt, AK Buell, ...
Journal of molecular biology 429 (20), 3018-3030, 2017
382017
Contact between the β1 and β2 Segments of α‐Synuclein that Inhibits Amyloid Formation
H Shaykhalishahi, A Gauhar, MM Wördehoff, CSR Grüning, AN Klein, ...
Angewandte Chemie International Edition 54 (30), 8837-8840, 2015
332015
Clustering of human prion protein and α-synuclein oligomers requires the prion protein N-terminus
NS Rösener, L Gremer, MM Wördehoff, T Kupreichyk, M Etzkorn, ...
Communications biology 3 (1), 365, 2020
292020
Uncovering the Binding and Specificity of β-Wrapins for Amyloid-β and α-Synuclein
AA Orr, MM Wördehoff, W Hoyer, P Tamamis
The Journal of Physical Chemistry B 120 (50), 12781-12794, 2016
282016
Seeded fibrillation as molecular basis of the species barrier in human prion diseases
L Luers, O Bannach, J Stöhr, MM Wördehoff, M Wolff, L Nagel-Steger, ...
PLoS One 8 (8), e72623, 2013
272013
Inhibitor and substrate cooperate to inhibit amyloid fibril elongation of α-synuclein
ED Agerschou, V Borgmann, MM Wördehoff, W Hoyer
Chemical science 11 (41), 11331-11337, 2020
182020
Characterization of a single-chain variable fragment recognizing a linear epitope of Aβ: a biotechnical tool for studies on Alzheimer’s disease?
S Dornieden, A Müller-Schiffmann, H Sticht, N Jiang, Y Cinar, ...
PloS one 8 (3), e59820, 2013
142013
β-Turn exchanges in the α-synuclein segment 44-TKEG-47 reveal high sequence fidelity requirements of amyloid fibril elongation
ED Agerschou, MP Schützmann, N Reppert, MM Wördehoff, ...
Biophysical chemistry 269, 106519, 2021
122021
A β-wrapin targeting the N-terminus of α-synuclein monomers reduces fibril-induced aggregation in neurons
ÉM Szegő, F Boß, D Komnig, C Gärtner, L Höfs, H Shaykhalishahi, ...
Frontiers in neuroscience 15, 696440, 2021
92021
α-Synuclein-derived lipoparticles in the study of α-Synuclein amyloid fibril formation
M Falke, J Victor, MM Wördehoff, A Peduzzo, T Zhang, GF Schröder, ...
Chemistry and physics of lipids 220, 57-65, 2019
92019
Kontakt zwischen den β1‐und β2‐Segmenten von α‐Synuclein inhibiert die Amyloidbildung
H Shaykhalishahi, A Gauhar, MM Wördehoff, CSR Grüning, AN Klein, ...
Angewandte Chemie 127 (30), 8962-8966, 2015
62015
A structural and kinetic link between membrane association and amyloid fibril formation of α-Synuclein
T Viennet, MM Wördehoff, B Uluca, C Poojari, H Shaykhalishahi, ...
BioRxiv, 173724, 2017
42017
Targeting the N-terminus of α-synuclein Monomer Reduces Fibril-induced Aggregation in the Brain
ÉM Szegõ, ÉM Szegő, F Boß, D Komnig, C Gärtner, L Höfs, ...
12020
Sequence-based identification of amyloidogenic β-hairpins reveals a prostatic acid phosphatase fragment promoting semen amyloid formation
LF Heid, ED Agerschou, AA Orr, T Kupreichyk, W Schneider, ...
Computational and Structural Biotechnology Journal 23, 417-430, 2024
2024
Phase separation and aggregation of α-synuclein diverge at different salt conditions
R Sternke-Hoffmann, X Sun, A Menzel, M Wördehoff, W Hoyer, W Zheng, ...
Biophysical Journal 123 (3), 220a, 2024
2024
The Kinetics of α-Synuclein Aggregation: Single Fibril Growth, β1-β2 Contacts, Membrane Environments and Dityrosine Formation
M Wördehoff
2017
Engineered binding proteins to amyloidogenic intrinsically disordered proteins
H Shaykhalishahi, E Mirecka, A Gauhar, C Gruening, M Woerdehoff, ...
PROTEIN SCIENCE 24, 123-123, 2015
2015
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