Mesenchymal stem cell-derived extracellular vesicles as mediators of anti-inflammatory effects: endorsement of macrophage polarization C Lo Sicco, D Reverberi, C Balbi, V Ulivi, E Principi, L Pascucci, ... Stem cells translational medicine 6 (3), 1018-1028, 2017 | 478 | 2017 |
Regulation of human macrophage M1–M2 polarization balance by hypoxia and the triggering receptor expressed on myeloid cells-1 F Raggi, S Pelassa, D Pierobon, F Penco, M Gattorno, F Novelli, A Eva, ... Frontiers in immunology 8, 1097, 2017 | 273 | 2017 |
Hypoxia downregulates the expression of activating receptors involved in NK‐cell‐mediated target cell killing without affecting ADCC M Balsamo, C Manzini, G Pietra, F Raggi, F Blengio, MC Mingari, ... European journal of immunology 43 (10), 2756-2764, 2013 | 264 | 2013 |
Hypoxia modifies the transcriptome of primary human monocytes: modulation of novel immune-related genes and identification of CC-chemokine ligand 20 as a new hypoxia-inducible gene MC Bosco, M Puppo, C Santangelo, L Anfosso, U Pfeffer, P Fardin, ... The Journal of immunology 177 (3), 1941-1955, 2006 | 225 | 2006 |
Monocytes and dendritic cells in a hypoxic environment: Spotlights on chemotaxis and migration MC Bosco, M Puppo, F Blengio, T Fraone, P Cappello, M Giovarelli, ... Immunobiology 213 (9-10), 733-749, 2008 | 223 | 2008 |
Immunizing and curative potential of replicating and nonreplicating murine mammary adenocarcinoma cells engineered with interleukin (IL)-2, IL-4, IL-6, IL-7, IL-10, tumor … A Allione, M Consalvo, P Nanni, PL Lollini, F Cavallo, M Giovarelli, ... Cancer research 54 (23), 6022-6026, 1994 | 218 | 1994 |
Inhibition of tumor growth and enhancement of metastasis after transfection of the γ‐interferon gene PL Lollini, MC Bosco, F Cavallo, C De Giovanni, M Giovarelli, L Landuzzi, ... International journal of cancer 55 (2), 320-329, 1993 | 145 | 1993 |
Hypoxia modulates the gene expression profile of immunoregulatory receptors in human mature dendritic cells: identification of TREM-1 as a novel hypoxic marker in vitro and in vivo MC Bosco, D Pierobon, F Blengio, F Raggi, C Vanni, M Gattorno, A Eva, ... Blood, The Journal of the American Society of Hematology 117 (9), 2625-2639, 2011 | 144 | 2011 |
Interleukin-2 and human monocyte activation I Espinoza-Delgado, MC Bosco, T Musso, GL Gusella, DL Longo, ... Journal of Leucocyte Biology 57 (1), 13-19, 1995 | 142 | 1995 |
The tryptophan catabolite picolinic acid selectively induces the chemokines macrophage inflammatory protein-1α and-1β in macrophages MC Bosco, A Rapisarda, S Massazza, G Melillo, H Young, L Varesio The Journal of Immunology 164 (6), 3283-3291, 2000 | 133 | 2000 |
Hypoxia modifies the transcriptome of human NK cells, modulates their immunoregulatory profile, and influences NK cell subset migration M Parodi, F Raggi, D Cangelosi, C Manzini, M Balsamo, F Blengio, A Eva, ... Frontiers in immunology 9, 418208, 2018 | 120 | 2018 |
IL-2 up-regulates but IFN-gamma suppresses IL-8 expression in human monocytes. GL Gusella, T Musso, MC Bosco, I Espinoza-Delgado, K Matsushima, ... Journal of immunology (Baltimore, Md.: 1950) 151 (5), 2725-2732, 1993 | 120 | 1993 |
Low doses of IL-4 injected perilymphatically in tumor-bearing mice inhibit the growth of poorly and apparently nonimmunogenic tumors and induce a tumor-specific immune memory. M Bosco, M Giovarelli, M Forni, A Modesti, S Scarpa, L Masuelli, G Forni Journal of immunology (Baltimore, Md.: 1950) 145 (9), 3136-3143, 1990 | 120 | 1990 |
Hypoxia selectively inhibits monocyte chemoattractant protein-1 production by macrophages MC Bosco, M Puppo, S Pastorino, Z Mi, G Melillo, S Massazza, ... The Journal of Immunology 172 (3), 1681-1690, 2004 | 116 | 2004 |
Topotecan inhibits vascular endothelial growth factor production and angiogenic activity induced by hypoxia in human neuroblastoma by targeting hypoxia-inducible factor-1α and-2α M Puppo, F Battaglia, C Ottaviano, S Delfino, D Ribatti, L Varesio, ... Molecular cancer therapeutics 7 (7), 1974-1984, 2008 | 93 | 2008 |
Interferon-gamma upregulates interleukin-8 gene expression in human monocytic cells by a posttranscriptional mechanism MC Bosco, GL Gusella, I Espinoza-Delgado, DL Longo, L Varesio | 75 | 1994 |
The hypoxic environment reprograms the cytokine/chemokine expression profile of human mature dendritic cells F Blengio, F Raggi, D Pierobon, P Cappello, A Eva, M Giovarelli, ... Immunobiology 218 (1), 76-89, 2013 | 74 | 2013 |
Hypoxia inhibits the expression of the CCR5 chemokine receptor in macrophages MC Bosco, G Reffo, M Puppo, L Varesio Cellular immunology 228 (1), 1-7, 2004 | 69 | 2004 |
Engineering of macrophages to produce IFN-γ in response to hypoxia L Carta, S Pastorino, G Melillo, MC Bosco, S Massazza, L Varesio The Journal of Immunology 166 (9), 5374-5380, 2001 | 66 | 2001 |
Chronic hypoxia reprograms human immature dendritic cells by inducing a proinflammatory phenotype and TREM‐1 expression D Pierobon, MC Bosco, F Blengio, F Raggi, A Eva, M Filippi, T Musso, ... European journal of immunology 43 (4), 949-966, 2013 | 65 | 2013 |