Molecular mechanisms of ROS production and oxidative stress in diabetes P Newsholme, VF Cruzat, KN Keane, R Carlessi, PIH de Bittencourt Jr Biochemical Journal 473 (24), 4527-4550, 2016 | 792 | 2016 |
Molecular events linking oxidative stress and inflammation to insulin resistance and β-cell dysfunction KN Keane, VF Cruzat, R Carlessi, PIH De Bittencourt, P Newsholme Oxidative medicine and cellular longevity 2015, 2015 | 389 | 2015 |
Pleiotropic effects of GLP-1 and analogs on cell signaling, metabolism, and function J Rowlands, J Heng, P Newsholme, R Carlessi Frontiers in endocrinology 9, 420454, 2018 | 214 | 2018 |
Oxidative stress pathways in pancreatic β-cells and insulin-sensitive cells and tissues: importance to cell metabolism, function, and dysfunction P Newsholme, KN Keane, R Carlessi, V Cruzat American Journal of Physiology-Cell Physiology 317 (3), C420-C433, 2019 | 182 | 2019 |
Mechanisms of vitamin D action in skeletal muscle KR Montenegro, V Cruzat, R Carlessi, P Newsholme Nutrition research reviews 32 (2), 192-204, 2019 | 97 | 2019 |
GLP-1 receptor signalling promotes β-cell glucose metabolism via mTOR-dependent HIF-1α activation R Carlessi, Y Chen, J Rowlands, VF Cruzat, KN Keane, L Egan, ... Scientific reports 7 (1), 2661, 2017 | 97 | 2017 |
Death-associated protein kinase increases glycolytic rate through binding and activation of pyruvate kinase I Mor, R Carlessi, T Ast, E Feinstein, A Kimchi Oncogene 31 (6), 683-693, 2012 | 57 | 2012 |
The bioenergetics of inflammation: insights into obesity and type 2 diabetes KN Keane, EK Calton, R Carlessi, PH Hart, P Newsholme European journal of clinical nutrition 71 (7), 904-912, 2017 | 56 | 2017 |
Human pancreatic islet transplantation: an update and description of the establishment of a pancreatic islet isolation laboratory J Rheinheimer, AC Bauer, SP Silveiro, AAF Estivalet, AP Bouças, ... Archives of endocrinology and metabolism 59, 161-170, 2015 | 51 | 2015 |
Effects of vitamin D on primary human skeletal muscle cell proliferation, differentiation, protein synthesis and bioenergetics KR Montenegro, R Carlessi, V Cruzat, P Newsholme The Journal of steroid biochemistry and molecular biology 193, 105423, 2019 | 45 | 2019 |
Cloning and purification of recombinant proteins of Mycoplasma hyopneumoniae expressed in Escherichia coli S Simionatto, SB Marchioro, V Galli, DD Hartwig, RM Carlessi, FM Munari, ... Protein expression and purification 69 (2), 132-136, 2010 | 43 | 2010 |
GTP binding to the ROC domain of DAP‐kinase regulates its function through intramolecular signalling R Carlessi, V Levin‐Salomon, S Ciprut, S Bialik, H Berissi, S Albeck, ... EMBO reports 12 (9), 917-923, 2011 | 41 | 2011 |
Exendin-4 protects rat islets against loss of viability and function induced by brain death R Carlessi, NE Lemos, AL Dias, FS Oliveira, LA Brondani, LH Canani, ... Molecular and cellular endocrinology 412, 239-250, 2015 | 28 | 2015 |
Oleoyl-lysophosphatidylinositol enhances glucagon-like peptide-1 secretion from enteroendocrine L-cells through GPR119 SA Arifin, S Paternoster, R Carlessi, I Casari, JH Ekberg, T Maffucci, ... Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2018 | 26 | 2018 |
Different digestion enzymes used for human pancreatic islet isolation: a mixed treatment comparison (MTC) meta-analysis J Rheinheimer, PK Ziegelmann, R Carlessi, LR Reck, AC Bauer, ... Islets 6 (4), e977118, 2014 | 26 | 2014 |
Mouse models of hepatocellular carcinoma R Carlessi, J Köhn-Gaone, J Olynyk, N Tirnitz-Parker Hepatocellular carcinoma, 2019 | 22 | 2019 |
Lupin seed hydrolysate promotes G-protein-coupled receptor, intracellular Ca2+ and enhanced glycolytic metabolism-mediated insulin secretion from BRIN-BD11 pancreatic beta cells M Tapadia, R Carlessi, S Johnson, R Utikar, P Newsholme Molecular and cellular endocrinology 480, 83-96, 2019 | 18 | 2019 |
Exendin‐4 attenuates brain death–induced liver damage in the rat R Carlessi, NE Lemos, AL Dias, LA Brondani, JR Oliveira, AC Bauer, ... Liver Transplantation 21 (11), 1410-1418, 2015 | 18 | 2015 |
Insulin and IGF-1 receptor autocrine loops are not required for Exendin-4 induced changes to pancreatic β-cell bioenergetic parameters and metabolism in BRIN-BD11 cells J Rowlands, V Cruzat, R Carlessi, P Newsholme Peptides 100, 140-149, 2018 | 15 | 2018 |
Pigment epithelium-derived factor stimulates skeletal muscle glycolytic activity through NADPH oxidase-dependent reactive oxygen species production R Carnagarin, R Carlessi, P Newsholme, AM Dharmarajan, CR Dass The international journal of biochemistry & cell biology 78, 229-236, 2016 | 15 | 2016 |