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Bibhu P Mishra
Bibhu P Mishra
Research Scientist, Broad Institute
E-mail confirmado em dartmouth.edu
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The histone methyltransferase activity of MLL1 is dispensable for hematopoiesis and leukemogenesis
BP Mishra, KM Zaffuto, EL Artinger, T Org, HKA Mikkola, C Cheng, ...
Cell reports 7 (4), 1239-1247, 2014
1512014
An MLL-dependent network sustains hematopoiesis
EL Artinger, BP Mishra, KM Zaffuto, BE Li, EKY Chung, AW Moore, ...
Proceedings of the National Academy of Sciences 110 (29), 12000-12005, 2013
902013
Dynamic association of MLL1, H3K4 trimethylation with chromatin and Hox gene expression during the cell cycle
BP Mishra, KI Ansari, SS Mandal
The FEBS journal 276 (6), 1629-1640, 2009
852009
Human CpG binding protein interacts with MLL1, MLL2 and hSet1 and regulates Hox gene expression
KI Ansari, BP Mishra, SS Mandal
Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1779 (1), 66-73, 2008
772008
MLL histone methylases in gene expression, hormone signaling and cell cycle
KI Ansari, BP Mishra, SS Mandal
Front Biosci 14, 3483-3495, 2009
632009
Mixed lineage leukaemia-4 regulates cell-cycle progression and cell viability and its depletion suppresses growth of xenografted tumour in vivo
KI Ansari, S Kasiri, BP Mishra, SS Mandal
British journal of cancer 107 (2), 315-324, 2012
392012
CRISPR/Cas9 Genome Editing to Treat Sickle Cell Disease and B-Thalassemia: Re-Creating Genetic Variants to Upregulate Fetal Hemoglobin Appear Well-Tolerated, Effective and Durable.
MI Lin, E Paik, B Mishra, D Burkhardt, A Kernytsky, M Pettiglio, YS Chen, ...
Blood 130, 284, 2017
202017
HOXA5 expression is elevated in breast cancer and is transcriptionally regulated by estradiol
I Hussain, P Deb, A Chini, M Obaid, A Bhan, KI Ansari, BP Mishra, ...
Frontiers in Genetics 11, 592436, 2020
112020
MLL1 promotes IL-7 responsiveness and survival during B cell differentiation
T Gan, BE Li, BP Mishra, KL Jones, P Ernst
The Journal of Immunology 200 (5), 1682-1691, 2018
112018
Crispr/Cas9-mediated genome editing of human CD34+ cells upregulate fetal hemoglobin to clinically relevant levels in single cell-derived Erythroid Colonies
B Mishra, S Chou, MI Lin, EJ Paik, Y Zhang, R Liang, K Tomkinson, ...
Blood 128 (22), 3623, 2016
62016
Re-creating hereditary persistence of fetal hemoglobin (HPFH) to treat sickle cell disease (SCD) and β-thalassemia
MI Lin, EJ Paik, BP Mishra, S Chou, Y Zhang, K Tomkinson, MA Pettiglio, ...
Blood 128 (22), 4708, 2016
42016
Materials and methods for treatment of hemoglobinopathies
T Chakraborty, BP Mishra, CA Cowan, AS Lundberg, S Kulkarni, ...
US Patent App. 16/758,990, 2021
32021
Materials and methods for treatment of hemoglobinopathies
T Chakraborty, BP Mishra
US Patent 11,268,077, 2022
22022
Compositions and methods for cd123 modification
J Lydeard, C Luo, BP Mishra, M Lin
US Patent App. 17/638,610, 2022
12022
Compositions and methods for cd33 modification
J Lydeard, BP Mishra
US Patent App. 17/613,387, 2022
12022
Re-creating hereditary persistence of fetal hemoglobin with CRISPR/CAS9 to treat sickle cell disease and beta-thalassemia
M Lin, E Paik, B Mishra, S Chou, D Burkhardt, A Kernytsky, M Pettiglio, ...
Haematologica 102, 23-24, 2017
12017
Deconvoluting MLL1-dependent pathways in hematopoiesis and leukemogenesis
BP Mishra, P Ernst
Leukemia Supplements 3 (1), S9-S10, 2014
12014
MLL1-dependent pathways and mechanisms that maintain hematopoiesis
E Artinger, B Mishra, B Li, K Zaffuto, C Cheng, T Org, H Mikkola, M Djabali, ...
Experimental Hematology 41 (8), S20, 2013
12013
Materials and methods for treatment of hemoglobinopathies
T Chakraborty, BP Mishra
US Patent App. 17/585,365, 2022
2022
Materials and methods for treatment of hemoglobinopathies
CA Cowan, AS Lundberg, T Chakraborty, I Michelle, LIN Ching, ...
US Patent App. 17/591,563, 2022
2022
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