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Andrew P. Latham
Andrew P. Latham
E-mail confirmado em ucsf.edu
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Maximum entropy optimized force field for intrinsically disordered proteins
AP Latham, B Zhang
Journal of chemical theory and computation 16 (1), 773-781, 2019
682019
Consistent force field captures homologue-resolved HP1 phase separation
AP Latham, B Zhang
Journal of chemical theory and computation 17 (5), 3134-3144, 2021
442021
Multiscale modeling of genome organization with maximum entropy optimization
X Lin, Y Qi, AP Latham, B Zhang
The Journal of chemical physics 155 (1), 2021
432021
Improving coarse-grained protein force fields with small-angle X-ray scattering data
AP Latham, B Zhang
The Journal of Physical Chemistry B 123 (5), 1026-1034, 2019
362019
Single-stranded nucleic acid binding and coacervation by linker histone H1
R Leicher, A Osunsade, GNL Chua, SC Faulkner, AP Latham, JW Watters, ...
Nature structural & molecular biology 29 (5), 463-471, 2022
292022
Unifying coarse-grained force fields for folded and disordered proteins
AP Latham, B Zhang
Current opinion in structural biology 72, 63-70, 2022
252022
On the stability and layered organization of protein-DNA condensates
AP Latham, B Zhang
Biophysical Journal 121 (9), 1727-1737, 2022
202022
Phosphorylation-dependent conformations of the disordered carboxyl-terminus domain in the epidermal growth factor receptor
R Regmi, S Srinivasan, AP Latham, V Kukshal, W Cui, B Zhang, R Bose, ...
The journal of physical chemistry letters 11 (23), 10037-10044, 2020
102020
CO-induced restructuring on stepped Pt surfaces: a molecular dynamics study
JR Michalka, AP Latham, JD Gezelter
The Journal of Physical Chemistry C 120 (32), 18180-18190, 2016
102016
Molecular determinants for the layering and coarsening of biological condensates
AP Latham, B Zhang
Aggregate 3 (6), e306, 2022
92022
Structure and dynamics of N-glycosylated human ribonuclease 1
HR Kilgore, AP Latham, VT Ressler, B Zhang, RT Raines
Biochemistry 59 (34), 3148-3156, 2020
82020
Frustrated Microphase Separation Produces Interfacial Environment within Biological Condensates
AP Latham, L Zhu, DA Sharon, S Ye, AP Willard, X Zhang, B Zhang
bioRxiv, 2023.03. 30.534967, 2023
42023
Micropolarity governs the structural organization of biomolecular condensates
S Ye, AP Latham, Y Tang, CH Hsiung, J Chen, F Luo, Y Liu, B Zhang, ...
Nature chemical biology 20 (4), 443-451, 2024
32024
OpenABC enables flexible, simplified, and efficient GPU accelerated simulations of biomolecular condensates
S Liu, C Wang, AP Latham, X Ding, B Zhang
PLoS Computational Biology 19 (9), e1011442, 2023
22023
Microphase Separation Produces Interfacial Environment within Diblock Biomolecular Condensates
AP Latham, L Zhu, DA Sharon, S Ye, AP Willard, X Zhang, B Zhang
eLife 12, 2024
2024
A map of osteosarcoma cell architecture reveals convergence of pediatric cancer mutations on protein assemblies
M Hu, LV Schaffer, EL Huttlin, G Qian, A Latham, A Pal, LP Vaites, T Le, ...
Cancer Research 84 (6_Supplement), 6543-6543, 2024
2024
A global multiscale map of protein assemblies from integration of protein interactions and images
LV Schaffer, M Hu, EL Huttlin, G Qian, A Pal, N Soni, A Latham, LP Vaites, ...
Cancer Research 84 (6_Supplement), 2348-2348, 2024
2024
Utilizing Molecular Simulations to Examine Nanosuspension Stability
AP Latham, ES Levy, BD Sellers, DH Leung
Pharmaceutics 16 (1), 50, 2023
2023
Tools for assembling the cell: Towards the era of cell structural bioinformatics
M Hu, X Zhang, A Latham, A Šali, T Ideker, E Lundberg
PACIFIC SYMPOSIUM ON BIOCOMPUTING 2024, 661-665, 2023
2023
Maximum Entropy Optimization: a General Approach to Study Ordered and Disordered Proteins Reveals Key Features of Protein Phase Separation
AP Latham
Massachusetts Institute of Technology, 2022
2022
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