Purdue University
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Exploring polyethylenimine‐mediated DNA transfection and the proton sponge hypothesis
A Akinc, M Thomas, AM Klibanov, R Langer
The Journal of Gene Medicine: A cross‐disciplinary journal for research on …, 2005
Conjugation to gold nanoparticles enhances polyethylenimine's transfer of plasmid DNA into mammalian cells
M Thomas, AM Klibanov
Proceedings of the National Academy of Sciences 100 (16), 9138-9143, 2003
Non-viral gene therapy: polycation-mediated DNA delivery
M Thomas, AM Klibanov
Applied microbiology and biotechnology 62 (1), 27-34, 2003
Enhancing polyethylenimine's delivery of plasmid DNA into mammalian cells
M Thomas, AM Klibanov
Proceedings of the National Academy of Sciences 99 (23), 14640-14645, 2002
Full deacylation of polyethylenimine dramatically boosts its gene delivery efficiency and specificity to mouse lung
M Thomas, JJ Lu, Q Ge, C Zhang, J Chen, AM Klibanov
Proceedings of the National Academy of Sciences 102 (16), 5679-5684, 2005
Cross-linked small polyethylenimines: while still nontoxic, deliver DNA efficiently to mammalian cells in vitro and in vivo
M Thomas, Q Ge, JJ Lu, J Chen, A Klibanov
Pharmaceutical research 22 (3), 373-380, 2005
Quantitative comparison of polyethylenimine formulations and adenoviral vectors in terms of intracellular gene delivery processes
CM Varga, NC Tedford, M Thomas, AM Klibanov, LG Griffith, ...
Gene therapy 12 (13), 1023-1032, 2005
Non-viral siRNA delivery to the lung
M Thomas, JJ Lu, J Chen, AM Klibanov
Advanced drug delivery reviews 59 (2-3), 124-133, 2007
Mechanistic studies on aggregation of polyethylenimine‐DNA complexes and its prevention
VK Sharma, M Thomas, AM Klibanov
Biotechnology and bioengineering 90 (5), 614-620, 2005
Ligand-targeted delivery of small interfering RNAs to malignant cells and tissues
M Thomas, SA Kularatne, L Qi, P Kleindl, CP Leamon, MJ Hansen, ...
Annals of the New York Academy of Sciences 1175 (1), 32, 2009
Synthesis of a novel thiazole based dipeptide chemosensor for Cu (II) in water
S Bhattacharya, M Thomas
Tetrahedron Letters 41 (52), 10313-10317, 2000
Identification of novel superior polycationic vectors for gene delivery by high-throughput synthesis and screening of a combinatorial library
M Thomas, JJ Lu, C Zhang, J Chen, AM Klibanov
Pharmaceutical research 24 (8), 1564-1571, 2007
Facile synthesis of oligopeptide distamycin analogs devoid of hydrogen bond donors or acceptors at the N-terminus: sequence-specific duplex DNA binding as a function of peptide …
S Bhattacharya, M Thomas
Tetrahedron Letters 41 (29), 5571-5575, 2000
Enhancement of plasmid DNA immunogenicity with linear polyethylenimine
EV Grant, M Thomas, J Fortune, AM Klibanov, NL Letvin
European journal of immunology 42 (11), 2937-2948, 2012
Distamycin Analogues without Leading Amide at Their N‐Termini − Comparative Binding Properties to AT‐ and GC‐Rich DNA Sequences
M Thomas, U Varshney, S Bhattacharya
European Journal of Organic Chemistry 2002 (21), 3604-3615, 2002
DNA binding properties of novel distamycin analogs that lack the leading amide unit at the N-terminus
S Bhattacharya, M Thomas
Biochemical and biophysical research communications 267 (1), 139-144, 2000
Real time, noninvasive imaging and quantitation of the accumulation of ligand-targeted drugs into receptor-expressing solid tumors
E Vlashi, JE Sturgis, M Thomas, PS Low
Molecular Pharmaceutics 6 (6), 1868-1875, 2009
Optimized protocol for the large scale production of HIV pseudovirions by transient transfection of HEK293T cells with linear fully deacylated polyethylenimine
G Devitt, M Thomas, AM Klibanov, T Pfeiffer, V Bosch
Journal of virological methods 146 (1-2), 298-304, 2007
Evaluation of novel prostate-specific membrane antigen-targeted near-infrared imaging agent for fluorescence-guided surgery of prostate cancer
SA Kularatne, M Thomas, CH Myers, P Gagare, AK Kanduluru, CJ Crian, ...
Clinical Cancer Research 25 (1), 177-187, 2019
Polycation-mediated delivery of siRNAs for prophylaxis and treatment of influenza virus infection
M Thomas, Q Ge, JJ Lu, AM Klibanov, J Chen
Expert Opinion on Biological Therapy 5 (4), 495-505, 2005
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