| Synthesis of DNA-Interactive Pyrrolo[2,1-c][1,4]benzodiazepines (PBDs) D Antonow, DE Thurston Chemical reviews 111 (4), 2815-2864, 2011 | 284 | 2011 |
| Structure−Activity Relationships of Monomeric C2-Aryl Pyrrolo[2,1-c][1,4]benzodiazepine (PBD) Antitumor Agents D Antonow, M Kaliszczak, GD Kang, M Coffils, AC Tiberghien, N Cooper, ... Journal of medicinal chemistry 53 (7), 2927-2941, 2010 | 118 | 2010 |
| Pre-clinical pharmacology and mechanism of action of SG3199, the pyrrolobenzodiazepine (PBD) dimer warhead component of antibody-drug conjugate (ADC) payload tesirine JA Hartley, MJ Flynn, JP Bingham, S Corbett, H Reinert, A Tiberghien, ... Scientific reports 8 (1), 10479, 2018 | 112 | 2018 |
| Parallel Synthesis of a Novel C2-Aryl Pyrrolo[2,1-c][1,4]benzodiazepine (PBD) Library D Antonow, N Cooper, PW Howard, DE Thurston Journal of Combinatorial Chemistry 9 (3), 437-445, 2007 | 92 | 2007 |
| Investigation of the protein alkylation sites of the STAT3: STAT3 inhibitor Stattic by mass spectrometry S Heidelberger, G Zinzalla, D Antonow, S Essex, BP Basu, J Palmer, ... Bioorganic & medicinal chemistry letters 23 (16), 4719-4722, 2013 | 58 | 2013 |
| Synthesis of a novel C2-aryl pyrrolo [2, 1-c][1, 4] benzodiazepine-5, 11-dione library: Effect of C2-aryl substitution on cytotoxicity and non-covalent DNA binding D Antonow, TC Jenkins, PW Howard, DE Thurston Bioorganic & medicinal chemistry 15 (8), 3041-3053, 2007 | 52 | 2007 |
| Deoxo-Fluor-mediated cyclodehydration of β-hydroxy thioamides to the corresponding thiazolines SG Mahler, GL Serra, D Antonow, E Manta Tetrahedron Letters 42 (46), 8143-8146, 2001 | 50 | 2001 |
| Solution Structure of a 2:1 C2-(2-Naphthyl) Pyrrolo[2,1-c][1,4]benzodiazepine DNA Adduct: Molecular Basis for Unexpectedly High DNA Helix Stabilization D Antonow, T Barata, TC Jenkins, GN Parkinson, PW Howard, ... Biochemistry 47 (45), 11818-11829, 2008 | 34 | 2008 |
| Facile oxidation of electron-poor benzo [b] thiophenes to the corresponding sulfones with an aqueous solution of H 2 O 2 and P 2 O 5 D Antonow, T Marrafa, I Dawood, T Ahmed, MR Haque, DE Thurston, ... Chemical communications 46 (13), 2289-2291, 2010 | 26 | 2010 |
| A novel small-molecule inhibitor of IL-6 signalling G Zinzalla, MR Haque, BP Basu, J Anderson, SL Kaye, S Haider, F Hasan, ... Bioorganic & medicinal chemistry letters 20 (23), 7029-7032, 2010 | 25 | 2010 |
| An efficient monitoring technique for solid-phase reactions by KBr pellets/FT-IR using methyl p-aminobenzoate synthesis assisted by microwave radiation on merrifield resin D Antonow, CS Graebin, VL Eifler-Lima Journal of the Brazilian Chemical Society 15, 782-785, 2004 | 14 | 2004 |
| Optimization of the antitumor activity of sequence-specific pyrrolobenzodiazepine derivatives based on their affinity for ABC transporters M Kaliszczak, D Antonow, KI Patel, P Howard, DI Jodrell, DE Thurston, ... The AAPS journal 12, 617-627, 2010 | 13 | 2010 |
| Naphthalene Peri Annelated N,N‐ and N,O‐Heterocycles: The Effect of Heteroatom‐Guided Peri‐Fusion on Their Structure and Reactivity Profiles‐A Theoretical … D Tzeli, P Kozielewicz, M Zloh, D Antonow, PG Tsoungas, ID Petsalakis ChemistrySelect 3 (33), 9743-9752, 2018 | 10 | 2018 |
| Tetracycline analogues with a selective inhibitory effect on HIF-1α Y Bendiabdellah, KM Rahman, B Uranchimeg, KS Nahar, D Antonow, ... MedChemComm 5 (7), 923-926, 2014 | 9 | 2014 |
| Synthesis of 2, 4-disubstituted thiazole combinatorial unit on solid-phase: microwave assisted conversion of alcohol to amine monitored by FT-IR D Antonow, SG Mahler, GL Serra, E Manta, VL Eifler-Lima Journal of the Brazilian Chemical Society 16, 477-481, 2005 | 9 | 2005 |
| Synthesis of 2, 4-disubstituted thiazole combinatorial unit on solid-phase: microwave assisted conversion of alcohol to amine monitored by FT-IR D Antonow, SG Mahler, GL Serra, E Manta, VL Eifler-Lima Journal of the Brazilian Chemical Society 16, 477-481, 2005 | 9 | 2005 |
| Fragment-based approaches and the prospect of fragmented prodrugs D Antonow Drug Discovery Today 15 (19-20), 801-803, 2010 | 7 | 2010 |
| Pyrrolo[2,1-c][1,4]benzodiazepine (PBD) analogues show differential substrate specificity to ABC transporters M Kaliszczak, D Antonow, K Patel, D Jodrell, P Howard, D Thurston, ... Cancer Research 68 (9_Supplement), 3226-3226, 2008 | 1 | 2008 |
| Synthetic, structural and biological studies on c2-substituted pyrrolo [2, 1-c][1, 4] benzodiazepines D Antonow PQDT-Global, 2008 | 1 | 2008 |
| Total synthesis of YM-181741 for the preparation of natural product-like STAT3: STAT3 inhibitors A Misale, D Antonow, DE Thurston, G Zinzalla ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 240, 2010 | | 2010 |
