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Haiyang Yun
Haiyang Yun
E-mail confirmado em med.uni-heidelberg.de
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Fumarate is an epigenetic modifier that elicits epithelial-to-mesenchymal transition
M Sciacovelli, E Gonçalves, TI Johnson, VR Zecchini, ASH Da Costa, ...
Nature 537 (7621), 544-547, 2016
5172016
Incidence and prognostic influence of DNMT3A mutations in acute myeloid leukemia
HM Thol F, Damm F, Lüdeking A, Winschel C, Wagner K, Morgan M, Yun H ...
J Clin Oncol 29, 2889-2896, 2011
4742011
Prognostic Significance of ASXL1 Mutations in Patients With Myelodysplastic Syndromes
F Thol, I Friesen, F Damm, H Yun, EM Weissinger, J Krauter, K Wagner, ...
Journal of Clinical Oncology 29 (18), 2499-2506, 2011
3492011
Mutant IDH1 promotes leukemogenesis in vivo and can be specifically targeted in human AML
A Chaturvedi, MM Araujo Cruz, N Jyotsana, A Sharma, H Yun, K Görlich, ...
Blood, The Journal of the American Society of Hematology 122 (16), 2877-2887, 2013
2412013
Single Nucleotide Polymorphism in the Mutational Hotspot of WT1 Predicts a Favorable Outcome in Patients With Cytogenetically Normal Acute Myeloid Leukemia
F Damm, M Heuser, M Morgan, H Yun, A Großhennig, G Göhring, ...
Journal of Clinical Oncology 28 (4), 578-585, 2010
1552010
Glutaminolysis is a metabolic dependency in FLT3ITD acute myeloid leukemia unmasked by FLT3 tyrosine kinase inhibition
P Gallipoli, G Giotopoulos, K Tzelepis, ASH Costa, S Vohra, ...
Blood 131 (15), 1639-1653, 2018
1482018
UTX-mediated enhancer and chromatin remodeling suppresses myeloid leukemogenesis through noncatalytic inverse regulation of ETS and GATA programs
M Gozdecka, E Meduri, M Mazan, K Tzelepis, M Dudek, AJ Knights, ...
Nature genetics 50 (6), 883-894, 2018
1362018
Cell of origin in AML: susceptibility to MN1-induced transformation is regulated by the MEIS1/AbdB-like HOX protein complex
M Heuser, H Yun, T Berg, E Yung, B Argiropoulos, F Kuchenbauer, ...
Cancer cell 20 (1), 39-52, 2011
1132011
Contrasting requirements during disease evolution identify EZH2 as a therapeutic target in AML
F Basheer, G Giotopoulos, E Meduri, H Yun, M Mazan, D Sasca, ...
Journal of Experimental Medicine 216 (4), 966-981, 2019
1022019
Rare occurrence of DNMT3A mutations in myelodysplastic syndromes
F Thol, C Winschel, A Lüdeking, H Yun, I Friesen, F Damm, K Wagner, ...
Haematologica 96 (12), 1870, 2011
1002011
Early loss of Crebbp confers malignant stem cell properties on lymphoid progenitors
SJ Horton, G Giotopoulos, H Yun, S Vohra, O Sheppard, ...
Nature cell biology 19 (9), 1093-1104, 2017
692017
Epigenetics in myelodysplastic syndromes
M Heuser, H Yun, F Thol
Seminars in cancer biology 51, 170-179, 2018
652018
Genetic characterization of acquired aplastic anemia by targeted sequencing
M Heuser, C Schlarmann, V Dobbernack, V Panagiota, L Wiehlmann, ...
Haematologica 99 (9), e165, 2014
642014
Genetic variations of DNA repair genes and their prognostic significance in patients with acute myeloid leukemia
JY Shi, ZH Ren, B Jiao, R Xiao, HY Yun, B Chen, WL Zhao, Q Zhu, ...
International journal of cancer 128 (1), 233-238, 2011
612011
Cohesin-dependent regulation of gene expression during differentiation is lost in cohesin-mutated myeloid malignancies
D Sasca, H Yun, G Giotopoulos, J Szybinski, T Evan, NK Wilson, ...
Blood 134 (24), 2195-2208, 2019
472019
Prognostic significance of combined MN1, ERG, BAALC, and EVI1 (MEBE) expression in patients with myelodysplastic syndromes
F Thol, H Yun, AK Sonntag, F Damm, EM Weissinger, J Krauter, K Wagner, ...
Annals of hematology 91 (8), 1221-1233, 2012
472012
Constitutive IRF8 expression inhibits AML by activation of repressed immune response signaling
A Sharma, H Yun, N Jyotsana, A Chaturvedi, A Schwarzer, E Yung, ...
Leukemia 29 (1), 157-168, 2015
422015
A new fusion gene NUP98-IQCG identified in an acute T-lymphoid/myeloid leukemia with at (3; 11)(q29q13; p15) del (3)(q29) translocation
Q Pan, YJ Zhu, BW Gu, X Cai, XT Bai, HY Yun, J Zhu, B Chen, L Weng, ...
Oncogene 27 (24), 3414-3423, 2008
342008
Impact of MLL5 expression on decitabine efficacy and DNA methylation in acute myeloid leukemia
H Yun, F Damm, D Yap, A Schwarzer, A Chaturvedi, N Jyotsana, ...
haematologica 99 (9), 1456, 2014
302014
Mutational synergy during leukemia induction remodels chromatin accessibility, histone modifications and three-dimensional DNA topology to alter gene expression
H Yun, N Narayan, S Vohra, G Giotopoulos, A Mupo, P Madrigal, D Sasca, ...
Nature genetics 53 (10), 1443-1455, 2021
212021
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