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Maorong Chen
Maorong Chen
Boston Children’s Hospital, Harvard Medical School
E-mail confirmado em childrens.harvard.edu
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Structural and molecular basis of ZNRF3/RNF43 transmembrane ubiquitin ligase inhibition by the Wnt agonist R-spondin
M Zebisch, Y Xu, C Krastev, BT MacDonald, M Chen, RJC Gilbert, X He, ...
Nature communications 4 (1), 2787, 2013
1912013
Volumetric compression induces intracellular crowding to control intestinal organoid growth via Wnt/β-catenin signaling
Y Li, M Chen, J Hu, R Sheng, Q Lin, X He, M Guo
Cell stem cell 28 (1), 63-78. e7, 2021
852021
Compression-induced dedifferentiation of adipocytes promotes tumor progression
Y Li, AS Mao, BR Seo, X Zhao, SK Gupta, M Chen, YL Han, TY Shih, ...
Science advances 6 (4), eaax5611, 2020
782020
Single-molecule dynamics of Dishevelled at the plasma membrane and Wnt pathway activation
W Ma, M Chen, H Kang, Z Steinhart, S Angers, X He, MW Kirschner
Proceedings of the National Academy of Sciences 117 (28), 16690-16701, 2020
512020
Structural basis for toxin resistance of β4-associated calcium-activated potassium (BK) channels
G Gan, H Yi, M Chen, L Sun, W Li, Y Wu, J Ding
Journal of biological chemistry 283 (35), 24177-24184, 2008
482008
UNC-31/CAPS docks and primes dense core vesicles in C. elegans neurons
XG Lin, M Ming, MR Chen, WP Niu, YD Zhang, B Liu, YM Jiu, JW Yu, T Xu, ...
Biochemical and biophysical research communications 397 (3), 526-531, 2010
462010
A novel Golgi retention signal RPWS for tumor suppressor UBIAD1
X Wang, D Wang, P Jing, Y Wu, Y Xia, M Chen, L Hong
PloS one 8 (8), e72015, 2013
412013
Synaptotagmin IV regulates dense core vesicle (DCV) release in LβT2 cells
ZT Hu, MR Chen, Z Ping, YM Dong, RY Zhang, T Xu, ZX Wu
Biochemical and biophysical research communications 371 (4), 781-786, 2008
242008
Lysine-rich extracellular rings formed by hβ2 subunits confer the outward rectification of BK channels
M Chen, G Gan, Y Wu, L Wang, Y Wu, J Ding
PloS one 3 (5), e2114, 2008
242008
SCFβ-TRCP E3 ubiquitin ligase targets the tumor suppressor ZNRF3 for ubiquitination and degradation
Y Ci, X Li, M Chen, J Zhong, BJ North, H Inuzuka, X He, Y Li, J Guo, X Dai
Protein & Cell 9 (10), 879-889, 2018
192018
Development of an integrated microfluidic device for evaluating of in vivo chemo-sensing of intact Caenorhabditis elegans
J Wang, Z Li, Z Xu, L Hu, X Feng, M Chen, W Du, Z Wu, Q Luo, T Xu, ...
Sensors and Actuators B: Chemical 178, 343-349, 2013
182013
Aberrant Cholesterol Metabolism and Wnt/β‐Catenin Signaling Coalesce via Frizzled5 in Supporting Cancer Growth
S Zheng, J Lin, Z Pang, H Zhang, Y Wang, L Ma, H Zhang, X Zhang, ...
Advanced Science 9 (28), 2200750, 2022
172022
TMEM79/MATTRIN defines a pathway for Frizzled regulation and is required for Xenopus embryogenesis
M Chen, N Amado, J Tan, A Reis, M Ge, JG Abreu, X He
Elife 9, e56793, 2020
152020
Four-turn α-helical segment prevents surface expression of the auxiliary hβ2 subunit of BK-type channel
C Lv, M Chen, G Gan, L Wang, T Xu, J Ding
Journal of biological chemistry 283 (5), 2709-2715, 2008
132008
A novel fluorescent timer based on bicistronic expression strategy in Caenorhabditis elegans
MR Chen, S Yang, W Niu, ZY Li, LF Meng, ZX Wu
Biochemical and biophysical research communications 395 (1), 82-86, 2010
112010
APC deficiency leads to β-catenin stabilization and signaling independent of LRP5/6
M Chen, X He
Developmental Cell 49 (6), 825-826, 2019
82019
Generation of the compression-induced dedifferentiated adipocytes (CiDAs) using hypertonic medium
Y Li, AS Mao, BR Seo, X Zhao, SK Gupta, M Chen, YL Han, TY Shih, ...
Bio-protocol 11 (4), e3920-e3920, 2021
52021
USP10 strikes down β-catenin by dual-wielding deubiquitinase activity and phase separation potential
Y Wang, A Mao, J Liu, P Li, S Zheng, T Tong, Z Li, H Zhang, L Ma, J Lin, ...
Cell Chemical Biology 30 (11), 1436-1452. e10, 2023
22023
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