Andrew I. Webb
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The pseudokinase MLKL mediates necroptosis via a molecular switch mechanism
JM Murphy, PE Czabotar, JM Hildebrand, IS Lucet, JG Zhang, ...
Immunity 39 (3), 443-453, 2013
Linear ubiquitination prevents inflammation and regulates immune signalling
B Gerlach, SM Cordier, AC Schmukle, CH Emmerich, E Rieser, TL Haas, ...
Nature 471 (7340), 591-596, 2011
Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death
JM Hildebrand, MC Tanzer, IS Lucet, SN Young, SK Spall, P Sharma, ...
Proceedings of the National Academy of Sciences 111 (42), 15072-15077, 2014
A type III effector antagonizes death receptor signalling during bacterial gut infection
JS Pearson, C Giogha, SY Ong, CL Kennedy, M Kelly, KS Robinson, ...
Nature 501 (7466), 247-251, 2013
Familial autoinflammation with neutrophilic dermatosis reveals a regulatory mechanism of pyrin activation
SL Masters, V Lagou, I Jéru, PJ Baker, L Van Eyck, DA Parry, D Lawless, ...
Science translational medicine 8 (332), 332ra45-332ra45, 2016
CIS is a potent checkpoint in NK cell–mediated tumor immunity
RB Delconte, TB Kolesnik, LF Dagley, J Rautela, W Shi, EM Putz, ...
Nature Immunology 17 (7), 816-824, 2016
Lack of prominent peptide–major histocompatibility complex features limits repertoire diversity in virus-specific CD8+ T cell populations
SJ Turner, K Kedzierska, H Komodromou, NL La Gruta, MA Dunstone, ...
Nature immunology 6 (4), 382-389, 2005
EspL is a bacterial cysteine protease effector that cleaves RHIM proteins to block necroptosis and inflammation
JS Pearson, C Giogha, S Mühlen, U Nachbur, CLL Pham, Y Zhang, ...
Nature microbiology 2 (4), 1-10, 2017
A RIPK2 inhibitor delays NOD signalling events yet prevents inflammatory cytokine production
U Nachbur, CA Stafford, A Bankovacki, Y Zhan, LM Lindqvist, BK Fiil, ...
Nature communications 6 (1), 1-13, 2015
Conformational switching of the pseudokinase domain promotes human MLKL tetramerization and cell death by necroptosis
EJ Petrie, JJ Sandow, AV Jacobsen, BJ Smith, MDW Griffin, IS Lucet, ...
Nature communications 9 (1), 1-15, 2018
Functional and structural characteristics of NY-ESO-1-related HLA A2-restricted epitopes and the design of a novel immunogenic analogue
AI Webb, MA Dunstone, W Chen, MI Aguilar, Q Chen, H Jackson, ...
Journal of Biological Chemistry 279 (22), 23438-23446, 2004
Necroptosis signalling is tuned by phosphorylation of MLKL residues outside the pseudokinase domain activation loop
MC Tanzer, A Tripaydonis, AI Webb, SN Young, LN Varghese, C Hall, ...
Biochemical Journal 471 (2), 255-265, 2015
Lectin switching during dengue virus infection
W Dejnirattisai, AI Webb, V Chan, A Jumnainsong, A Davidson, ...
Journal of Infectious Diseases 203 (12), 1775-1783, 2011
Constraints within major histocompatibility complex class I restricted peptides: presentation and consequences for T-cell recognition
A Theodossis, C Guillonneau, A Welland, LK Ely, CS Clements, ...
Proceedings of the National Academy of Sciences 107 (12), 5534-5539, 2010
VDAC2 enables BAX to mediate apoptosis and limit tumor development
H San Chin, MX Li, IKL Tan, RL Ninnis, B Reljic, K Scicluna, LF Dagley, ...
Nature communications 9 (1), 1-13, 2018
T cell determinants incorporating β-amino acid residues are protease resistant and remain immunogenic in vivo
AI Webb, MA Dunstone, NA Williamson, JD Price, A de Kauwe, W Chen, ...
The Journal of Immunology 175 (6), 3810-3818, 2005
Synthesis of biotinylated episilvestrol: highly selective targeting of the translation factors eIF4AI/II
JM Chambers, LM Lindqvist, A Webb, DCS Huang, GP Savage, ...
Organic letters 15 (6), 1406-1409, 2013
Epitope-specific TCRβ repertoire diversity imparts no functional advantage on the CD8+ T cell response to cognate viral peptides
NL La Gruta, PG Thomas, AI Webb, MA Dunstone, T Cukalac, PC Doherty, ...
Proceedings of the National Academy of Sciences 105 (6), 2034-2039, 2008
A class of γδ T cell receptors recognize the underside of the antigen-presenting molecule MR1
J Le Nours, NA Gherardin, SH Ramarathinam, W Awad, F Wiede, ...
Science 366 (6472), 1522-1527, 2019
RIPLET, and not TRIM25, is required for endogenous RIG‐I‐dependent antiviral responses
TJ Hayman, AC Hsu, TB Kolesnik, LF Dagley, J Willemsen, MD Tate, ...
Immunology and cell biology 97 (9), 840-852, 2019
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